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Factor XIa (Coagulation Factor XIa)

Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN). Factor XIa then activates factor IX to factor IXa in the presence of calcium.
Also Known As:
Coagulation Factor XIa; Activated Factor XI; Blood Coagulation Factor XI, Activated; Contact Activation Product; Factor 11A; Factor Eleven A; Factor XIa, Coagulation; Factor XI, Activated
Networked: 116 relevant articles (8 outcomes, 16 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Butenas, Saulius: 9 articles (01/2022 - 01/2008)
2. Gailani, David: 8 articles (12/2021 - 08/2006)
3. Undas, Anetta: 7 articles (01/2022 - 01/2008)
4. Ten Cate, Hugo: 6 articles (01/2022 - 01/2016)
5. Al-Horani, Rami A: 5 articles (11/2020 - 02/2013)
6. Bozarth, Jeffrey M: 4 articles (01/2022 - 02/2014)
7. Luettgen, Joseph M: 4 articles (01/2022 - 02/2014)
8. Wexler, Ruth R: 4 articles (01/2022 - 02/2014)
9. Wong, Pancras C: 4 articles (01/2022 - 02/2014)
10. Seiffert, Dietmar: 3 articles (09/2022 - 02/2014)

Related Diseases

1. Hemorrhage
2. Thrombosis (Thrombus)
3. Stroke (Strokes)
4. Venous Thromboembolism
5. Atrial Fibrillation

Related Drugs and Biologics

1. Fibrinolytic Agents (Antithrombotic Agents)
2. Anticoagulants
3. milvexian
4. Glycoproteins (Glycoprotein)
5. Factor XIIa (Coagulation Factor XIIa)
6. Factor XI (Plasma Thromboplastin Antecedent)
7. Plasma Kallikrein
8. Factor IX (Coagulation Factor IX)
9. Peptides (Polypeptides)
10. High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)

Related Therapies and Procedures

1. Therapeutics
2. Knee Replacement Arthroplasty (Total Knee Replacement)
3. Secondary Prevention
4. Orthopedic Procedures
5. Punctures