Complement C5a (Complement 5a)
The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal ARGININE that is crucial for its spasmogenic activity. Of all the complement-derived anaphylatoxins, C5a is the most potent in mediating immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE), smooth MUSCLE CONTRACTION; HISTAMINE RELEASE; and migration of LEUKOCYTES to site of INFLAMMATION.
Also Known As:
Complement 5a; C5a Complement; Complement Component 5a; C5a, Complement; Complement, C5a; Component 5a, Complement
Networked: 190
relevant articles (5 outcomes,
19 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Woodruff, Trent M:
11 articles
(01/2022 - 07/2011)
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2. | Lambris, John D:
5 articles
(01/2022 - 12/2003)
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3. | Vater, Axel:
5 articles
(01/2022 - 04/2013)
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4. | Taylor, Stephen M:
5 articles
(10/2019 - 01/2004)
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5. | Li, Gui-Qing:
4 articles
(01/2020 - 12/2017)
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6. | Tang, Ming:
4 articles
(01/2020 - 12/2017)
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7. | Xu, Gui-Lian:
4 articles
(01/2020 - 12/2017)
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8. | Ward, Peter A:
4 articles
(10/2018 - 01/2009)
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9. | Okada, Hidechika:
4 articles
(03/2016 - 06/2003)
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10. | Okada, Noriko:
4 articles
(03/2016 - 06/2003)
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