Monokines

03/01/2005 - "These shortly activated CD56+ cells show high killer activity against NK- and LAK-sensitive tumor targets that persists over a culture period of 18 days after two additional 6 h cycles of exposure to the monokines applied every 8 days and also retain their ability for high cytokine production during each exposure. "
11/01/1994 - "Because tumor growth primes M phi to produce several suppressor monokines, we determined if cancer induced M phi expression of these proto-oncogenes. "
02/01/1993 - "To further characterize monokines that cause inhibition of mitochondrial respiration in tumor cells, EA13.5 macrophage-like cells were isolated and selected for inhibition of mitochondrial respiration in EMT-6 tumor cells. "
11/15/1989 - "The sensitivity of tumor cell targets to these monokines was also modified by the treatment sequence. "
07/15/1988 - "Anti-IL-1 and/or anti-TNF sera neutralized the cytolysis of tumor cells mediated by free monokines, by fixed monocytes, or by plasma membrane preparations. "

12/01/1994 - "carinii infection responded with a moderate increase in release of all three monokines. "
10/01/1993 - "The role of monokines produced during this infection was analysed. "
06/01/1989 - "Aged and protein-malnourished hosts have diminished febrile responses and increased morbidity and mortality from infection that could be due to deficiencies in the production of certain monokines. "
05/15/2001 - "During the innate immune response to infection, monocyte-derived cytokines (monokines), stimulate natural killer (NK) cells to produce immunoregulatory cytokines that are important to the host's early defense. "
02/01/1999 - "Here, we directly compare the release of chemokines and monokines by BMM raised either in serum-supplemented or in serum-free medium in response to Listeria monocytogenes EGD or Mycobacterium bovis BCG infection. "

03/17/1989 - "These studies demonstrated that endothelial cells may participate in neutrophil-mediated inflammation by synthesizing a chemotactic factor in response to specific monokines and LPS."
01/01/1990 - "Enhanced production of monokines can contribute to the enhanced inflammation in patients with spondyloarthropathies. "
01/01/1989 - "Monokines may contribute to the regulation of hematopoiesis and circulating numbers of leukocytes during chronic inflammation. "
12/01/1987 - "Circulating levels of both monokines do not appear to be a universal finding in inflammation."
05/01/1987 - "[Inflammation and production of monokines. "

03/01/1994 - "In conclusion, the present study showed that hepatic macrophages are in an activated state in sepsis as indicated by their increased production of inflammatory monokines and their increased expression of immunomodulatory surface molecules. "
10/01/1996 - "In these patients, Gramnegative sepsis, the symptoms of which are predominantly caused by LPS-induced release of monokines, represents a serious problem. "
10/01/1994 - "These findings suggest that the expression of specific functional molecules on peripheral blood leukocytes is variably related to the net production of certain monokines in sepsis."
02/01/1992 - "These results indicate that the spontaneous macrophage release of these monokines is comparable with that previously observed in endotoxin-sensitive mice, suggesting a common mechanism by which macrophages are primed by traumatic injury by an agent other than endotoxin to release monokines during sepsis. "
01/01/1991 - "Enhancement and hepatocyte-modulating effect of chemical mediators and monokines produced by hepatic macrophages in rats with induced sepsis."

05/01/1991 - "These same monokines can gain entrance into the circulation and act systemically to orchestrate the acute phase response. "
01/01/1989 - "The present results show that two kinds of monokines, hrIL-1 alpha and hrTNF, are intrinsically pyrogenic and induce the acute-phase response. "
03/01/1988 - "With the use of recombinant monokines, formal evidence for their participation in the acute phase response has been developed. "
07/01/1987 - "These findings demonstrate that altered glycosylation seen in plasma in some inflammatory states can be explained by the effects of monokines on glycosylation in hepatocytes and that gene expression and glycosylation of some APP during the acute-phase response may be regulated by different mechanisms."
07/16/1985 - "Monocyte derived cytokines (monokines) mimicked the acute phase response of all four parameters in vivo. "