Monokines

02/01/1997 - "[Levels of monokines in peripheral monocytes in patients with superficial tumors of the bladder treated with BCG. "
11/01/1994 - "Because tumor growth primes M phi to produce several suppressor monokines, we determined if cancer induced M phi expression of these proto-oncogenes. "
02/01/1993 - "To further characterize monokines that cause inhibition of mitochondrial respiration in tumor cells, EA13.5 macrophage-like cells were isolated and selected for inhibition of mitochondrial respiration in EMT-6 tumor cells. "
11/15/1989 - "The sensitivity of tumor cell targets to these monokines was also modified by the treatment sequence. "
11/15/1989 - "These are pleiotropic monokines which, in addition to affecting proliferation and differentiation of lymphocytes, act on various targets, including vascular cells and liver, and may therefore be involved in the pathogenesis of certain manifestations of malignancy. "

12/01/1994 - "carinii infection responded with a moderate increase in release of all three monokines. "
10/01/1993 - "The role of monokines produced during this infection was analysed. "
01/01/1993 - "Interestingly, two mRNAs found to be refractory to JHMV infection encode monokines, suggesting a role in pathogenesis. "
05/15/2001 - "During the innate immune response to infection, monocyte-derived cytokines (monokines), stimulate natural killer (NK) cells to produce immunoregulatory cytokines that are important to the host's early defense. "
02/01/1999 - "Here, we directly compare the release of chemokines and monokines by BMM raised either in serum-supplemented or in serum-free medium in response to Listeria monocytogenes EGD or Mycobacterium bovis BCG infection. "

03/01/1997 - "The temporal as well as spatial dissociation between expression of T cell-derived cytokines and monokines indicates that T cell-independent mechanisms may also be of importance in the triggering of monokine production during arthritis."
09/01/1985 - "[Significance of interleukin 1 and related monokines in the pathogenesis of chronic polyarthritis]."
01/01/1988 - "In addition to hyperreactive PMNs, monocytes from patients with previous yersinia arthritis, but also from healthy HLA-B27 positive subjects, respond to stimulation with lipopolysaccharide by enhanced production of inflammatory monokines compared with HLA-B27 negative healthy controls. "
01/01/2021 - "The superior efficacy of IRAK4i over anti-TNF or anti-IL-6R therapy in miR-Let7b-induced arthritis or CIA was due to the ability of IRAK4i therapy to restrain the migration of joint F480+iNOS+ MΦs, vimentin+ fibroblasts, and CD3+ T cells, in addition to negating the expression of a wide range of monokines, including IL-12, MIP2, and IRF5 and Th1/Th17 lymphokines. "

04/01/1993 - "Human monocyte-derived macrophages (M phi) from the majority of normal donors respond to inoculation with Mycobacterium avium, serotype 4, (MAI) by elaboration of the inflammatory monokines TNF-alpha, IL-1 beta, and IL-6, which are of central importance for the protection against bacterial and parasitic infections. "

01/01/1989 - "Monokines may contribute to the regulation of hematopoiesis and circulating numbers of leukocytes during chronic inflammation. "
11/15/1988 - "These data demonstrate that monokines play an important role in mediating acute inflammation via induction of an endothelial cell-derived NCF."
11/15/1988 - "Monokines have been increasingly recognized as communication signals that interact with both immune and non-immune cells during inflammation. "
12/01/1987 - "Circulating levels of both monokines do not appear to be a universal finding in inflammation."
05/01/1987 - "[Inflammation and production of monokines. "