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Heparin Cofactor II

A sulfated plasma protein with a MW of approximately 66kDa that resembles ANTITHROMBIN III. The protein is an inhibitor of thrombin in plasma and is activated by dermatan sulfate or heparin. It is a member of the serpin superfamily.
Also Known As:
Heparin Co-Factor II; Heparin Cofactor 2; Leuserpin 2; Protease Inhibitor Leuserpin 2; Serpin D1; Heparin Co Factor II; Heparin cofactor II
Networked: 151 relevant articles (3 outcomes, 16 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Matsumoto, Toshio: 7 articles (12/2021 - 02/2004)
2. Aihara, Ken-ichi: 6 articles (10/2012 - 02/2004)
3. Akaike, Masashi: 6 articles (10/2012 - 02/2004)
4. Tollefsen, Douglas M: 6 articles (07/2011 - 01/2002)
5. Ikeda, Yasumasa: 5 articles (12/2021 - 06/2004)
6. Azuma, Hiroyuki: 5 articles (10/2009 - 02/2004)
7. Sata, Masataka: 4 articles (10/2012 - 06/2007)
8. Takamori, Nobuyuki: 4 articles (04/2009 - 02/2004)
9. Yoshida, Sumiko: 3 articles (12/2021 - 04/2009)
10. Iwase, Takashi: 3 articles (10/2012 - 06/2007)

Related Diseases

1. Atherosclerosis
2. Infections
3. Septic Shock (Toxic Shock Syndrome)
4. Thrombosis (Thrombus)
5. Venous Thrombosis (Deep-Vein Thrombosis)

Related Drugs and Biologics

1. Serine Proteinase Inhibitors (Serine Protease Inhibitors)
2. Serpins
3. Peptides (Polypeptides)
4. Protein S
5. Protein C
6. Thrombin
7. Antithrombin III
8. Prothrombin (Factor II)
9. Antithrombins
10. Thrombomodulin

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Critical Care (Surgical Intensive Care)
4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
5. Stents