HLA-A2 Antigen (HLA A2 Antigen)

Human histocompatibility (HLA) surface antigen encoded by the A locus on chromosome 6. The HLA-A2 antigen is associated with recognition of the INFLUENZA A VIRUS.
Also Known As:
HLA A2 Antigen; HLA-A2; HLA-A2.1; Antigen, HLA-A2
Networked: 699 relevant articles (22 outcomes, 69 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Itoh, Kyogo: 12 articles (11/2009 - 05/2002)
2. Harada, Mamoru: 8 articles (05/2015 - 07/2003)
3. Berzofsky, Jay A: 7 articles (01/2013 - 04/2004)
4. Reiter, Yoram: 7 articles (04/2012 - 07/2002)
5. Romero, Pedro: 7 articles (10/2010 - 05/2002)
6. Shichijo, Shigeki: 7 articles (11/2009 - 05/2002)
7. Noguchi, Masanori: 7 articles (11/2009 - 07/2003)
8. Speiser, Daniel E: 6 articles (01/2014 - 10/2002)
9. Kiessling, Rolf: 6 articles (01/2011 - 11/2002)
10. Knuth, Alexander: 6 articles (10/2010 - 01/2002)

Related Diseases

1. Neoplasms (Cancer)
08/12/1998 - "We report here that not only monocyte-derived dendritic cells but also activated T cells incubated with the MAGE-3 antigenic peptide presented by HLA-A2 were effective in activating specific CTL precursors present in the blood of individuals without cancer. "
01/01/2007 - "Here we report the results of a phase I clinical study of intensive course NY-ESO-1 peptide vaccination, evaluating the safety, immunogenicity and clinical response in HLA-A2 positive patients with NY-ESO-1 expressing cancers. "
09/01/2005 - "Binding studies revealed its ability to decorate Ag-positive human tumor cells with covalent peptide single-chain HLA-A2 (scHLA-A2) molecules in a manner that was entirely dependent upon the specificity of the targeting Antibody fragment. "
04/25/2000 - "The objectives of the present study were (i) to develop enzyme-linked immunospot (ELISPOT) and tetramer assays to measure CD8(+) T cell responses to NY-ESO-1, (ii) to determine the frequency of CD8(+) T cell responses to NY-ESO-1 in a series of HLA-A2 patients with NY-ESO-1 expressing tumors, (iii) to determine the relation between CD8(+) T cell and humoral immune responses to NY-ESO-1, and (iv) to compare results of NY-ESO-1 ELISPOT assays performed independently in two laboratories with T cells from the same patients. "
02/15/1994 - "Results from in vitro studies of immune response to Epstein-Barr virus have found that the HLA-A2 antigen efficiently presents the EBV gene product LMP-2, which has been detected in NPC tumor cells. "
2. Melanoma (Melanoma, Malignant)
3. Infection
4. Neoplasm Metastasis (Metastasis)
5. Experimental Melanoma

Related Drugs and Biologics

1. Antigens
2. MART-1 Antigen
3. Epitopes
4. Peptides
5. HLA-A3 Antigen (HLA A3 Antigen)
6. T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)
7. DNA (Deoxyribonucleic Acid)
8. HLA-A*0201 antigen
9. Proteins (Proteins, Gene)
10. Amino Acids

Related Therapies and Procedures

1. Immunotherapy
2. Transplantation (Transplant Recipients)
3. Homologous Transplantation (Allograft)
4. Injections
5. Transplants (Transplant)