CD Antigens

Differentiation antigens residing on mammalian leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similar reactivity with certain subpopulations of antigens of a particular lineage or differentiation stage. The subpopulations of antigens are also known by the same CD designation.

Also Known As:

Networked: 38 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Belov, Larissa: 3 articles (11/2012 - 06/2009)
2.	Christopherson, Richard I: 3 articles (11/2012 - 06/2009)
3.	Huang, Pauline: 2 articles (11/2012 - 01/2010)
4.	Mulligan, Stephen P: 2 articles (01/2010 - 06/2009)
5.	Nguyen, Lisa: 2 articles (04/2009 - 07/2004)
6.	Lal, Sean: 2 articles (04/2009 - 07/2004)
7.	Eleutério Souza, P R: 1 article (01/2015)
8.	Martins Esteves, F A: 1 article (01/2015)
9.	de Albuquerque Maranhão, R M: 1 article (01/2015)
10.	Segat, L: 1 article (01/2015)

Related Diseases

1.	Leukemia 06/01/2001 - "Different leukemias express on their plasma membranes particular subsets of the 247 defined cluster of differentiation (CD) antigens, which may resemble those of precursor cells along the lineages of differentiation to mature myeloid and lymphoid leukocytes. " 07/01/1992 - "In the present study, the leukemia and lymphoma cell lines were analyzed by flow cytometry for appropriate CD antigens; all but 1 line showed patterns of expression consistent with their reported derivations. " 04/15/2006 - "Immunophenotyping, which utilizes panels of lineage-associated monoclonal antibodies to recognize clusters of differentiation (CD) antigens expressed on various leukocytes, plays a key role in the clinical diagnosis of acute leukemias. " 01/01/2003 - "Acute leukemia displays characteristic patterns of surface antigen expression (CD antigens), which facilitate their identification and proper classification and hence play an important role in instituting proper treatment plans. " 06/01/2001 - "We have developed a rapid, simple procedure, which enables concurrent determination of 50 or more CD antigens on leukocytes or leukemia cells in a single analysis using a microarray of antibodies. "
2.	Lymphoma (Lymphomas) 07/01/1992 - "In the present study, the leukemia and lymphoma cell lines were analyzed by flow cytometry for appropriate CD antigens; all but 1 line showed patterns of expression consistent with their reported derivations. " 01/15/1989 - "Using 14 well-defined (clustered) monoclonal antibodies (MAbs) against B-cell restricted/associated differentiation and activation (CD) antigens and 12 mediastinal clear-cell lymphomas (MCCL), 46 follicular-center-cell lymphomas (FCCL), and 20 non-neoplastic lymph nodes--including toxoplasmic and HIV-associated lymphadenitis--were immunohistochemically examined to determine the histogenesis of MCCL. " 06/01/1993 - "The most important recent developments include availability of antibodies to leukocyte CD-antigens to nearly comprehensive lymphoma typing in paraffin sections, use of certain leukocyte antigens in typing of solid tumours, e.g. "
3.	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 02/01/1997 - "56.2% of paediatric T-ALLs arise from intrathymic compartment II, 34.2% from compartment III and 9.6% from compartment I. Among adults, 45.3% arise from compartment I. 33.9% from compartment III and 20.8% from compartment II. The most frequently observed CD antigens in our study group are CD7, 5, 2 and 3. A correlative study of socioeconomic status reveals that 67.5% of T-ALL cases occurred among lower socioeconomic strata." 01/01/2008 - "Our aim was to select a suitable template by using the differential expression of OAcSGP along with other known CD antigens to monitor MRD in peripheral blood (PB) and bone marrow (BM) of Indian patients with B- or T-ALL during treatment and correlate it with the disease status. "
4.	Retroviridae Infections (Infection, Retrovirus) 07/01/1993 - "Together with mAbs against various rabbit CD antigens that we reported previously, these neutralizing mAbs to IL-2R alpha will be valuable for studies of human retrovirus infections, such as those induced by HTLV-1 or HIV, in rabbits."
5.	Celiac Disease (Celiac Sprue) 01/01/2015 - "The aim of this research was to study polymorphisms in the genes encoding cytokines interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) in patients with celiac disease (CD) antigens DQ2 (DQ2-positive) or DQ8 (DQ8-positive). "

Related Drugs and Biologics

1.	Cytokines
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4.	Monoclonal Antibodies
5.	Antibodies
6.	Transferrin Receptors (Transferrin Receptor)
7.	Proteins (Proteins, Gene)
8.	Clusterin
9.	CD98 Antigens
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