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Hyperostosis

Increase in the mass of bone per unit volume.
Also Known As:
Bone Hypertrophies; Hyperostoses; Hypertrophies, Bone; Hypertrophy, Bone; Bone Hypertrophy
Networked: 347 relevant articles (13 outcomes, 22 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Osteitis
2. Acne Vulgaris
3. Synovitis
4. Acquired Hyperostosis Syndrome (SAPHO Syndrome)
5. Back Pain (Backache)

Experts

1. Li, Chen: 9 articles (12/2021 - 05/2019)
2. Zhang, Wen: 6 articles (12/2021 - 05/2019)
3. Cao, Yihan: 5 articles (12/2021 - 07/2019)
4. Li, Li: 4 articles (01/2021 - 05/2019)
5. Li, Zhaohui: 3 articles (04/2021 - 01/2020)
6. Wang, Yutong: 2 articles (12/2021 - 04/2021)
7. Xiang, Yirong: 2 articles (12/2021 - 04/2021)
8. Xiong, Dingkun: 2 articles (04/2021 - 01/2021)
9. Zeng, Xiaofeng: 2 articles (04/2021 - 01/2021)
10. Brzosko, Marek: 2 articles (01/2021 - 08/2016)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hyperostosis:
1. Pamidronate (Aredia)FDA LinkGeneric
2. tofacitinibIBA
3. RetinoidsIBA
4. Diphosphonates (Bisphosphonates)IBA
5. LipidsIBA
6. Interleukin-23 Subunit p19IBA
7. Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
8. Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
9. Janus Kinase InhibitorsIBA
10. canakinumabFDA Link

Therapies and Procedures

1. Tonsillectomy
2. Decompression
3. Craniotomy
4. Therapeutics
5. Sutures (Suture)
05/01/2001 - "Qualitative histological examination revealed that at 84 days of age rabbits with suture and dura allografts had patent coronal sutures, suture-only allografts had fused coronal sutures with extensive endosteal hyperostosis, dura mater-only allografts had some new bone in the suturectomy site that resembled rudimentary osteogenic fronts, and suturectomy controls had extensive endosteal bone formation and resynostosis of the suturectomy site. "
01/01/1985 - "The extent of age dependency is diverse in various kinds of traits: 100.0% of hypostoses, 90.0% of hyperostoses, 50.0% of sutural and fontanel ossicles as well as additional and irregular sutures and only 30.0% of various openings are age related. "
10/01/1984 - "After cessation of treatment, cortical hyperostosis in the long bones remains, whereas the widening of the skull sutures regresses completely."
09/01/1996 - "Findings demonstrate that coronal suture synostosis in the congenital rabbit model (1) begins early during suture morphogenesis (before 25 days of gestation); (2) consistently radiates from a single focus corresponding to a normal interdigitating region (i.e., a high-tension environment); (3) varies in onset and rate as evidenced by low R2 value between age and extent of bony bridging; and (4) is the result of early hyperostosis of the osteogenic fronts and sutural agenesis. "
01/01/2021 - "Small skull with prominent frontal, maxillary prognathism, enamel hypoplasia, cribra orbitalia, porotic hyperostosis, proliferative reaction in the petrous portion of the temporal, obliterated sagittal suture, oval foramen magnum, and small mandible with masculine features. "