Omega-3 Fatty Acids (Omega 3 Fatty Acids)

A group of fatty acids, often of marine origin, which have the first unsaturated bond in the third position from the omega carbon. These fatty acids are believed to reduce serum triglycerides, prevent insulin resistance, improve lipid profile, prolong bleeding times, reduce platelet counts, and decrease platelet adhesiveness.

Also Known As:

Networked: 3035 relevant articles (268 outcomes, 715 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Harris, William S: 42 articles (06/2015 - 11/2002)
2.	Kang, Jing X: 33 articles (12/2015 - 03/2002)
3.	Calder, Philip C: 31 articles (04/2015 - 08/2002)
4.	Chapkin, Robert S: 17 articles (01/2016 - 06/2002)
5.	Mozaffarian, Dariush: 16 articles (07/2015 - 01/2005)
6.	Schmidt, Erik B: 14 articles (07/2015 - 07/2007)
7.	Geleijnse, Johanna M: 14 articles (05/2015 - 04/2006)
8.	Marchioli, Roberto: 14 articles (05/2015 - 04/2002)
9.	Mori, Trevor A: 13 articles (09/2015 - 11/2002)
10.	Kromhout, Daan: 13 articles (05/2015 - 04/2010)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2007 - "Use of n-3 fatty acids (FA) has been reported to be beneficial for cancer patients. " 05/01/2002 - "We determined if long-chain n-3 fatty acids fed as part of a: (1) high polyunsaturated fat diet (currently recommended by several health agencies) or (2) low polyunsaturated fat diet (representative of that consumed by a large segment of the North American population) improved antitumor immune defense and inhibited tumor growth. " 01/01/2008 - "These results suggest that 1:1 n-6/n-3 in the diet is effective in the prevention of mammary tumor development by increasing the n-3 PUFA content and reducing the expression of lipid metabolic-related genes." 02/01/1996 - "Results from animal studies suggest that omega-3 fatty acids from marine sources are protective against cancer. " 11/01/2005 - "Several investigations have adopted self-reported intake frequency of fish as a surrogate for intake of long-chain n-3 fatty acids, for which protective effects against cancer have been suggested. "
2.	Cardiovascular Diseases (Cardiovascular Disease) 01/01/2015 - "Hence, PL content in krill oil might play an important role in incorporation of n-3 PUFA into the RBC, conferring properties that render it effective in reducing cardiovascular disease (CVD) risk. " 01/01/2013 - "Data from research and clinical studies suggest that omega-3 fatty acids may be beneficial in metabolic syndrome-related conditions and can reduce the risk of cardiovascular disease. " 10/01/2007 - "High levels of n-3 fatty acids and other nutrients in traditional Inuit food appear to provide some protection against the typical diseases of affluent industrialized societies: cardiovascular diseases and type 2 diabetes. " 01/18/2007 - "[Omega-3-fatty acids still beneficial in cardiovascular disease]." 09/01/2003 - "Several investigations show that some components of the lipid fraction of the diet, such as omega-3 fatty acids, are beneficial with respect to cardiovascular disease, and these have become the centre of much attention. "
3.	Myocardial Infarction 01/01/2010 - "The Rischio and Prevenzione (R&P) project provides a feasible model to test the efficacy of n-3 polyunsaturated fatty acid therapy in patients at high cardiovascular risk with no history of myocardial infarction, and to assess how to implement recommended preventive strategies in general practice. " 07/01/2006 - "In the n-3 PUFA group, a significant reduction was seen in the number of myocardial infarctions (four versus 13; P = 0.036). " 01/01/2000 - "Currently, food sources rich in n-3 fatty acids are thought to be beneficial in secondary prophylaxis after a myocardial infarction. " 11/23/2002 - "Two clinical intervention trials show that prescription of fish or n-3 fatty acids to patients with prior myocardial infarction is effective in preventing mortality due to CHD. " 10/01/2004 - "Randomized controlled trials (RCTs) of the efficacy of omega-3 fatty acids among adults with recent or acute myocardial infarction (MI), or angina were selected. "
4.	Inflammation 01/01/2015 - "There is a strong pre-clinical evidence base demonstrating the efficacy of omega-3 fatty acids for ameliorating inflammation and thereby reducing disease burden. " 07/01/2013 - "Findings suggest that n-3 fatty acids have anti-inflammatory and immunopotentiating effects, and are beneficial in the wound healing process, particularly during early inflammation. " 07/01/2012 - "The question arises as to whether the decreased prevalence of these symptoms in the elderly with high n-3 PUFA consumption is also associated with improved central inflammation, i.e. " 08/01/2009 - "In conclusion, omega-3 fatty acids may be beneficial for preventing oxidative stress-induced pancreatic inflammation and apoptosis by inhibiting inflammatory cytokine and apoptotic gene expression of pancreatic acinar cells." 02/01/2006 - "Our findings support the notion that n-3 fatty acids may be beneficial in patients affected by diseases characterized by active inflammation."
5.	Crohn Disease (Crohn's Disease) 01/01/2000 - "Is fish oil (n-3 fatty acids) effective for the maintenance of remission in Crohn's disease?" 11/01/1995 - "Therapeutic efficacy of N-3 polyunsaturated fatty acid in experimental Crohn's disease." 01/01/2014 - "Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease." 01/01/2009 - "Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease." 09/01/2008 - "Omega-3 fatty acids for maintenance of remission of Crohn's disease."

Related Drugs and Biologics

1.	Antioxidants
2.	Eicosapentaenoic Acid
3.	Triglycerides (Triacylglycerol)
4.	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)
5.	Omega-6 Fatty Acids (Omega 6 Fatty Acids)
6.	Fish Oils
7.	Vitamin E
8.	Arginine (L-Arginine)
9.	Oils
10.	Non-alcoholic Fatty Liver Disease

Related Therapies and Procedures

1.	Enteral Nutrition (Feeding, Tube)
2.	Drug Therapy (Chemotherapy)
3.	Renal Dialysis (Hemodialysis)
4.	Parenteral Nutrition
5.	Fat-Restricted Diet (Diet, Fat Restricted)