HTLV-I Infections (HTLV-I Infection)

12/01/1996 - "These results demonstrate the protective efficacy of H-IgG against HTLV-I infection in a primate model and provide an experimental basis for passive immunization trials in humans."
12/01/1996 - "HTLV-I infection, as determined by seroconversion and verified by polymerase chain reaction, occurred in both of the N-IgG-injected macaques but in none of the four H-IgG-injected macaques. "
07/01/1991 - "HTLV-I infection did not affect the ability of B cells to secrete IgG. These findings suggest that HTLV-I cannot only infect cells of the T lineage, but can also infect B cells."
10/15/1990 - "To determine the ability of passive immunization to protect against HTLV-I infection, two groups of three rabbits were first transfused with 5 mL of blood from the same virus-infected rabbit and then infused after 24 or 48 hours with 10 mL of HTLV-I immune globulin (77 mg/mL of IgG) prepared from seropositive healthy persons. "
08/15/1989 - "These results indicate that hyperimmune IgG, but neither heat-inactivated HTLV-I nor env 175-196, were protective against HTLV-I infection induced by blood transfusion."

02/01/2002 - "stercoralis, with or without HTLV-I infection, were treated with albendazole, followed up for one year and separated into two groups, cured and non-cured. "

09/15/1987 - "Protection against human T-cell leukemia virus type-I (HTLV-I) infection in cynomolgus monkeys, achieved by immunizing the animals with env gene products of HTLV-I produced in Escherichia coli, was evaluated. "

12/15/1998 - "The data suggested that the substrate binding site of HTLV-I protease is different from the substrate binding sites of pepsin and HIV-1 protease, and that currently employed HIV-1 protease inhibitors would not be effective for the treatment of HTLV-I infections."

07/01/2000 - "Early diagnosis of HTLV-I infection in unusual syndromes and the use of corticosteroids may help to slow the development of the disease. "

12/15/1998 - "The data suggested that the substrate binding site of HTLV-I protease is different from the substrate binding sites of pepsin and HIV-1 protease, and that currently employed HIV-1 protease inhibitors would not be effective for the treatment of HTLV-I infections."

01/01/2012 - "Our study showed that e antigen expression is associated with a decreased risk of HTLV-I infection in northeast Iran."
07/01/1993 - "This study demonstrates that IFN beta is able to inhibit HTLV-I infection of CBMC through a mechanism that does not necessarily involve cell-mediated natural or antigen-dependent immunity afforded by CBMC subpopulations distinct from targets of HTLV-I infection. "
08/01/2015 - "Constructing Chimeric Antigen for Precise Screening of HTLV-I Infection."
04/01/2015 - "This specific antigen could be used as suitable agent for antibody-antigen based screening tests and can help clinicians in order to perform quick and precise screening of the HBV and HTLV-I infections. "
10/01/2014 - "Among the genes are involved in HTLV-I infection, the role of human leukocytes antigen (HLA) have been studied in different population. "

10/01/1999 - "We performed molecular pathologic studies of tonsils in individuals positive or negative for anti-HTLV-I antibodies (HTLV-I-Ab) to clarify histologic characteristics of tonsils in HTLV-I infection. "
09/01/1990 - "Although HTLV-I antibodies in these patients may not be related to blood transfusions, it seems prudent to screen blood donors for HTLV-I infection."
09/15/1989 - "In order to clarify the prevalence of human T-cell leukemia virus type I (HTLV-I) infection in the Kagoshima district, Japan, a highly endemic area for HTLV-I, antibodies for HTLV-I (anti-HTLV-I) were examined in the sera of 6167 from healthy residents and patients with various hematologic and nonhematologic diseases. "
02/01/1996 - "An additional study for the infection with HTLV-I revealed that the seropositivity for anti-HTLV-I antibodies was 11 (17.5%) of 63 patients with distinct uveitis entities and 38 (30.4%) of 125 patients with etiologically undefined uveitis, indicating no significant difference in HTLV-I infection between the two groups. "
12/01/1987 - "[An immunological study of human T-cell-leukemia virus type I (HTLV-I) infection (I)--Detection of low-titer anti-HTLV-I antibodies by HTLV-I associated membrane antigen (HTLV-MA) method]."

09/01/1997 - "We carried out a four years seroepidemiology surveillance study of HTLV-I infection among northeast Thai population by screening for antibodies to HTLV-I (anti-HTLV-I) in 1992, 1993, 1995 and 1997. "
01/01/1985 - "The spectra of reactivities of these antibodies with various simian cell lines derived by HTLV-I infection were different, as revealed by immunofluorescence studies. "
09/01/2006 - "The presence of HTLV-I infection was demonstrated by the detection of antibodies in serum and in cerebrospinal fluid by immunoenzymatic assay and Western blot analysis. "
12/01/2004 - "The immune response mounted during HTLV-I infection is primarily targeted against Tax with both Tax-specific antibodies and CTLs found in HTLV-I-infected individuals, indicating that Tax is available for immune recognition. "
06/01/1999 - "New donor status, advancing age, female sex, and positivity for hepatitis B virus core antibodies were the major factors associated with HTLV-I infection in Guadeloupe."

04/01/2005 - "In these studies and from our current report, we found 17 patients (22.1%) with HTLV-I infection among 77 ITP patients. "
09/01/2002 - "Thirty-seven patients with ITP were examined in the present study: 10 patients had HTLV-I infection, and the remaining 27 did not. "
04/01/2005 - "In the case of ITP patients with HTLV-I infection, the main etiology may be the increased destruction of platelets by immune system. "
04/01/2005 - "Therefore, the ITP patients with HTLV-I infection should receive eradication therapy in the case of H. "
04/01/2005 - "The prevalence of HTLV-I infection among ITP patients was higher than that of healthy volunteers (5 approximately 10%). "

11/01/2011 - "The HTLV-I Infection was associated with age (p<0.001), marital status (p<0.001), education (p = 0.047), and history of blood transfusion (p = 0.009), surgery (p<0.001), traditional cupping (p = 0.002), and hospitalization (p = 0.004). "
06/01/2001 - "ATL patients with seronegative mothers related the following risk factors for HTLV-I infection: 6 were breast-fed by surrogate mothers with unknown HTLV-I status, 4 had a sexually promiscuous behaviour and 1 had multiple blood transfusions at a young age. "
07/01/1998 - " In Brazil, serologic screening for HTLV-I infection should be performed upon pregnant women from endemic areas, Japanese immigrants or Japanese descendants, IV drug users (IVDU) or women whose partners are IVDUs, HIV carriers, pregnant women with promiscuous sexual behavior, and pregnant women who have received blood transfusions in areas where blood screening is not conducted. "
01/01/1998 - "Investigation of risk factors for HTLV-I infection in these individuals revealed that five out of 19 patients studied (26.3%) had received blood transfusions previous to disease onset."
04/01/1997 - "HTLV-I infection is caused by transmission of live infected lymphocytes from mother to child, from man to female, or by blood transfusion. "

04/15/2003 - "The authors are reporting the first documented case of HTLV-I infection in several transplant recipients sharing the same donor. "
08/15/2000 - "Since he was seronegative before the transplantation, it is suggested that HTLV-I infection was transmitted via renal graft transplantation. "
07/01/1999 - "A 39-year-old polytransfused patient with aplastic anemia acquired transfusion-associated HTLV-I infection shortly before transplantation. "

12/01/2005 - "Hemodialysis history was a common risk factor associated with HBV, HCV and HTLV-I infection. "
10/01/1987 - "The findings suggest an association between maintenance hemodialysis and HTLV-I infection, which can not be explained solely by blood or blood products."
07/01/1989 - "The clinical consequences of HTLV-I infection in relatively immunocompromised patients with chronic uremia who are undergoing chronic hemodialysis remains to be established."

07/01/2011 - "Adult T-cell leukaemia (ATL) is caused by human T-cell leukaemia virus type I (HTLV-I) infection and is resistant to conventional chemotherapy. "
08/01/1995 - "Immunodeficiency due to HTLV-I infection as well as chemotherapy for the preceding neoplasm are suggested to be related to the leukemogenesis of ATL."
01/15/2006 - "Adult T-cell leukemia (ATL), an aggressive malignancy of CD4+ T cells associated with human T-cell leukemia virus type I (HTLV-I) infection, carries a very poor prognosis because of the resistance of leukemic cells to any conventional regimen, including chemotherapy. "

10/27/1990 - "Decrease of HTLV-I infection in haemodialysis patients after donor screening."
10/01/1992 - "Before donor screening for HTLV-I, transfusion of 51,026 units resulted in two HTLV-I infections (0.0039%) and four HTLV-II infections (0.0078%). "