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Scleral Diseases

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General disorders of the sclera or white of the eye. They may include anatomic, embryologic, degenerative, or pigmentation defects.

Also Known As:

Sclera Diseases; Disease, Sclera; Disease, Scleral; Diseases, Sclera; Diseases, Scleral; Sclera Disease; Scleral Disease

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Eye Diseases: 2132
- Scleral Diseases: 5
  - Scleritis: 521
  - Daentl Towsend Siegel syndrome

Related Diseases

1.	Herpetic Keratitis
2.	Scleritis (Episcleritis)
3.	Melanoma (Melanoma, Malignant)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Scleral Diseases:

1.	Methylprednisolone FDA LinkGeneric 08/01/1988 - "This paper reviews current concepts in the management of scleral disease with emphasis on newer treatment modalities, such as pulse therapy with intravenously administered methylprednisolone or cyclophosphamide, and the use of orally administered cyclosporin." 01/01/1987 - "'Pulsed' immunosuppressive therapy, using methylprednisolone with or without cyclophosphamide, has effectively controlled severe destructive corneal and scleral disease that had been unresponsive to oral steroids. "
2.	Cyclophosphamide (Cytoxan)FDA LinkGeneric 08/01/1988 - "This paper reviews current concepts in the management of scleral disease with emphasis on newer treatment modalities, such as pulse therapy with intravenously administered methylprednisolone or cyclophosphamide, and the use of orally administered cyclosporin." 01/01/1987 - "'Pulsed' immunosuppressive therapy, using methylprednisolone with or without cyclophosphamide, has effectively controlled severe destructive corneal and scleral disease that had been unresponsive to oral steroids. "
3.	Fluorescein (Funduscein)FDA LinkGeneric 09/01/1985 - "Anterior segment fluorescein angiography in scleral disease reveals highly characteristic changes in the vasculature of the anterior segment associated with necrotising scleritis. "
4.	Cyclosporine (Ciclosporin)FDA LinkGeneric 08/01/1988 - "This paper reviews current concepts in the management of scleral disease with emphasis on newer treatment modalities, such as pulse therapy with intravenously administered methylprednisolone or cyclophosphamide, and the use of orally administered cyclosporin."
5.	SteroidsIBA 01/01/1987 - "'Pulsed' immunosuppressive therapy, using methylprednisolone with or without cyclophosphamide, has effectively controlled severe destructive corneal and scleral disease that had been unresponsive to oral steroids. "
6.	CollagenIBA 01/01/1996 - "The investigations were performed to describe regularities in the collagen architecture in normal and pathologically altered eyes to understand pathomorphologic and pathophysiologic changes in scleral diseases."

Therapies and Procedures

1.	Excimer Lasers 01/01/1990 - "[Treatment of corneal and scleral diseases with the excimer laser. "
2.	Corneal Transplantation (Keratoplasty) 01/01/1990 - "We treated certain corneal and scleral diseases with this laser: a malignant melanoma of the conjunctiva involving superficial scleral and limbal layers (1 eye), primary pterygia (19 eyes), recurrent erosion (45 eyes), persistent epithelial defect after keratoplasty (1 eye), and herpetic keratitis (6 eyes). "
3.	Lasers (Laser) 01/01/1990 - "We treated certain corneal and scleral diseases with this laser: a malignant melanoma of the conjunctiva involving superficial scleral and limbal layers (1 eye), primary pterygia (19 eyes), recurrent erosion (45 eyes), persistent epithelial defect after keratoplasty (1 eye), and herpetic keratitis (6 eyes). "