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Gastrinoma

A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).
Also Known As:
Ulcerogenic Islet Cell Tumor; Gastrin Producing Tumor; Gastrin-Producing Tumors; Gastrinomas; Tumor, Gastrin-Producing; Tumors, Gastrin-Producing; Gastrin-Producing Tumor; Islet Cell Tumor, Ulcerogenic
Networked: 873 relevant articles (50 outcomes, 73 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Zollinger-Ellison Syndrome (Syndrome, Zollinger-Ellison)
3. Carcinoid Tumor (Carcinoid)
4. Neoplasm Metastasis (Metastasis)
5. Insulinoma

Experts

1. Jensen, Robert T: 20 articles (04/2021 - 01/2002)
2. Rehfeld, Jens F: 10 articles (10/2016 - 02/2003)
3. Imamura, Masayuki: 9 articles (11/2017 - 10/2002)
4. Ito, Tetsuhide: 8 articles (04/2021 - 05/2005)
5. Komoto, Izumi: 7 articles (11/2017 - 10/2002)
6. Doi, Ryuichiro: 7 articles (01/2016 - 10/2002)
7. Gibril, Fathia: 7 articles (11/2006 - 01/2002)
8. Jensen, R T: 7 articles (07/2002 - 01/2000)
9. Anlauf, Martin: 6 articles (03/2016 - 11/2002)
10. Klöppel, Günter: 6 articles (03/2016 - 11/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Gastrinoma:
1. GastrinsIBA
2. Octreotide (Sandostatin)FDA LinkGeneric
3. Somatostatin Receptors (Somatostatin Receptor)IBA
4. SecretinFDA Link
5. AcidsIBA
6. Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
7. Hormones (Hormone)IBA
8. big gastrinIBA
9. CalciumIBA
10. AntralIBA

Therapies and Procedures

1. Therapeutics
2. Gastrectomy
3. Laparotomy
4. Drug Therapy (Chemotherapy)
5. Pancreatectomy