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DNA Probes

Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
Also Known As:
Conserved Gene Probes; DNA Hybridization Probes; Whole Chromosomal Probes; Whole Genomic DNA Probes; Chromosomal Probes, Whole; DNA Gene Probes; Gene Probes, Conserved; Hybridization Probe, DNA; Hybridization Probes, DNA; Probe, DNA; Probe, DNA Hybridization; Probes, Chromosomal; Probes, Conserved Gene; Probes, DNA; Probes, DNA Gene; Probes, DNA Hybridization; Probes, Whole Chromosomal; Chromosomal Probes; DNA Hybridization Probe; DNA Probe; Gene Probes, DNA
Networked: 1744 relevant articles (19 outcomes, 154 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Bogachev, Sergey S: 5 articles (10/2019 - 05/2016)
2. Efremov, Yaroslav R: 5 articles (10/2019 - 05/2016)
3. Potter, Ekaterina A: 5 articles (10/2019 - 05/2016)
4. Bayborodin, Sergey I: 4 articles (10/2019 - 05/2016)
5. Dolgova, Evgeniya V: 4 articles (10/2019 - 05/2016)
6. Liu, S: 4 articles (12/2000 - 01/2000)
7. Proskurina, Anastasia S: 3 articles (10/2019 - 02/2017)
8. Chernykh, Elena R: 3 articles (01/2019 - 02/2017)
9. Hanke, Wojciech: 3 articles (07/2016 - 09/2014)
10. Jakubowski, Lucjusz: 3 articles (07/2016 - 09/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Infections
3. Chromosome Aberrations (Chromosome Abnormalities)
4. Breast Neoplasms (Breast Cancer)
5. Down Syndrome (Down's Syndrome)

Related Drugs and Biologics

1. DNA (Deoxyribonucleic Acid)
2. Messenger RNA (mRNA)
3. Genetic Markers (Genetic Marker)
4. Nucleic Acids
5. Monoclonal Antibodies
6. Hepatitis B Surface Antigens (HBsAg)
7. Vaginal Creams, Foams, and Jellies (Vaginal Tablet)
8. Metronidazole (Metric)
9. Clindamycin (Cleocin)
10. MicroRNAs (MicroRNA)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics
3. Electrodes (Electrode)
4. Bone Marrow Transplantation (Transplantation, Bone Marrow)
5. Quantum Dots (Quantum Dot)