Cefotiam

One of the CEPHALOSPORINS that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

Also Known As:

Abbott-48999; CGP-14221-E; Cefotiam Hydrochloride; Ceradolan; Haloapor; Halospor; SCE-963; Abbott 48999; Abbott48999; CGP 14221 E; CGP14221E; Hydrochloride, Cefotiam; SCE 963; SCE963; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)acetyl)amino)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-trans)-

Networked: 179 relevant articles (17 outcomes, 28 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Nakamura, Atsushi: 4 articles (01/2022 - 10/2004)
2.	Asaoka, Minami: 2 articles (01/2022 - 04/2021)
3.	Etani, Toshiki: 2 articles (01/2022 - 04/2021)
4.	Iida, Keitaro: 2 articles (01/2022 - 04/2021)
5.	Kawai, Noriyasu: 2 articles (01/2022 - 04/2021)
6.	Kondo, Shuhei: 2 articles (01/2022 - 04/2021)
7.	Nagai, Takashi: 2 articles (01/2022 - 04/2021)
8.	Naiki, Taku: 2 articles (01/2022 - 04/2021)
9.	Wachino, Chiharu: 2 articles (01/2022 - 04/2021)
10.	Yanagita, Takeshi: 2 articles (01/2022 - 04/2021)

Related Diseases

1.	Infections 06/01/1982 - "This means that a high concentration of cefotiam dihydrochloride to intrathoracic tissue is effective against postoperative infection." 09/01/1986 - "Pharmacokinetic and clinical studies were carried out regarding the use of cefotiam (CTM) in the treatment of infections in newborn infants. " 01/01/1986 - "The results of the present study are consistent with a possible beneficial effect of cefotiam in the treatment of biliary tract infections." 10/01/1983 - "[Experimental and clinical studies of cefotiam for the treatment of otorhinolaryngological infections]." 10/01/1983 - "[Clinical studies of cefotiam in otorhinolaryngologic infections]."
2.	Respiratory Tract Infections (Respiratory Tract Infection) 07/01/1989 - "A multicentre trial with cefotiam in respiratory tract infections." 01/01/1982 - "These results confirm the excellent diffusion of cefotiam, especially in the respiratory tract, allowing bronchial levels largely superior to the minimum inhibitory concentrations required to kill the bacteria usually responsible for lower respiratory tract infections." 10/01/1985 - "Cefotiam therapy of lower respiratory tract infections." 10/01/1985 - "The results of this study suggest that cefotiam is an effective and well-tolerated antibiotic for the treatment of lower respiratory tract infections due to susceptible organisms." 10/01/1985 - "Cefotiam, a new cephalosporin, was evaluated in the treatment of lower respiratory tract infections in 29 patients. "
3.	Soft Tissue Infections 06/01/1984 - "Comparative efficacy of cefotiam versus cephalothin in the therapy of skin and soft tissue infections." 06/01/1984 - "Cefotiam was evaluated by a comparative open-label randomized trial with cephalothin in the therapy of skin and soft tissue infections in 39 patients. " 06/01/1984 - "Cefotiam was found to be as effective as cephalothin in the therapy of skin and soft tissue infections." 01/01/1990 - "To evaluate cefotiam concentrations at the active site in skin and soft-tissue infections, drug levels in skin suction blister fluid (SBF), cantharides blister fluid (CBF) and serum were determined. "
4.	Bacteremia 11/01/2020 - "We demonstrated cefotiam may be non-inferior to other antimicrobials of similar spectrum, in terms of survival rate, in EKP-induced bacteremia." 11/01/2020 - "Clinical evaluation of cefotiam in the treatment of bacteremia caused by Escherichia coli, Klebsiella species, and Proteus mirabilis: A retrospective study." 11/17/2017 - "Previous use of cefotiam and urinary catheter insertion may be risk factors for nosocomial enterococcal bacteremia in this case." 11/01/2020 - "As an antimicrobial, cefotiam may be an alternative to cefazolin; however, little evidence is available for its use in the treatment of bacteremia. " 11/01/2020 - "The purpose of this non-inferiority study was to retrospectively compare the therapeutic efficacy of cefotiam with some antimicrobials of narrow spectrum (cefazolin, cefmetazole, and flomoxef) in the treatment of EKP-induced bacteremia. "
5.	Surgical Wound Infection 01/01/2003 - "In accordance with the reviewed literature, this study confirms that one preoperative intravenous ('single shot') administration of Cefotiam is effective in decreasing the rate of postoperative wound infections in lumbar disc surgery." 01/01/1998 - "Cefotiam hydrochloride tablet was administered for postoperative wound infection of cardiac surgery. "

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Cefazolin (Ancef)
3.	Cefmenoxime (Cefmax)
4.	Cephalosporins (Cephalosporin Antibiotics)
5.	Cefmetazole (Cefmetazole Sodium)
6.	Fosfomycin
7.	Cephalothin (Cefalotin)
8.	Cefotaxime (Kendrick)
9.	Gentamicins (Gentamicin)
10.	Cefoperazone (Cefoperazone Sodium)

Related Therapies and Procedures

1.	Therapeutics
2.	Intravenous Administration
3.	Intravenous Infusions
4.	Continuous Ambulatory Peritoneal Dialysis (CAPD)
5.	Transurethral Resection of Bladder