Kassinin

Dodecapeptide tachykinin found in the central nervous system of the amphibian Kassina senegalensis. It is similar in structure and action to other tachykinins, but is especially effective in contracting smooth muscle tissue and stimulating the micturition reflex.

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Carballo-Pacheco, Martín: 1 article (07/2015)
2.	Ismail, Ahmed E: 1 article (07/2015)
3.	Strodel, Birgit: 1 article (07/2015)

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease) 07/30/2015 - "Here, we perform molecular dynamics simulations to study the aggregation of the amyloid-β peptide Aβ25-35, associated with Alzheimer's disease, and two functional amyloid-forming tachykinin peptides: kassinin and neuromedin K. "
2.	Dehydration (Water Stress) 01/01/1989 - "The development in infant rats of kassinin's potent and selective control of cell-dehydration thirst." 01/01/1989 - "The pattern of ontogenetic results described here may be that of a brain kassinin-like tachykinin that, in the course of the development of the neural structures on which it acts, gains potent and selective control of cell-dehydration thirst." 12/01/1988 - "In Wistar rats loaded with SC hypertonic NaCl solution kassinin produces an inhibition of cell-dehydration drinking which lasts several hours. "
3.	Carcinoid Tumor (Carcinoid) 11/01/1984 - "Antisera raised against eledoisin and kassinin detect elevated levels of immunoreactive material in plasma and tumor tissues from patients with carcinoid tumors." 09/01/1986 - "In addition, the plasma concentration of tachykinin [TKLI(K12)], using an assay that detects NKA, NPK, kassinin, eledoisin, and NKB, but not substance P and physalaemin, and the urinary excretion of 5-hydroxyindole acetic acid (5-HIAA) were measured in 20 patients with midgut carcinoid tumors before and during treatment with human leucocyte interferon. "
4.	Neoplasms (Cancer) 11/01/1984 - "Antisera raised against eledoisin and kassinin detect elevated levels of immunoreactive material in plasma and tumor tissues from patients with carcinoid tumors."
5.	Hypotension (Low Blood Pressure) 03/01/1987 - "The ability of six neurokinins (substance P, neurokinin A, neurokinin B, physalaemin, eledoisin and kassinin) to induce hypotension, salivary secretion and to activate motility of the duodenum and of the urinary bladder was investigated in urethane-anaesthetized rats. "

Related Drugs and Biologics

1.	Tachykinins
2.	Neurokinin B
3.	Peptides (Polypeptides)
4.	Amyloid (Amyloid Fibrils)
5.	Eledoisin
6.	Substance P
7.	Physalaemin
8.	Acetic Acid (Vinegar)
9.	Neurokinin A
10.	Urethane (Ethyl Carbamate)