HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Androstenediol

Subscribe to New Research on Androstenediol

An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-HYDROXYSTEROID DEHYDROGENASES).

Also Known As:

5-Androstene-3,17-diol; 5-Androstene-3beta-17beta-Diol; Androst-5-ene-3 beta,17 beta-Diol; Androst-5-ene-3,17-diol; Bisexovister; Delta 5-Androstenediol; Hermaphrodiol; Parke Davis Brand of Androstenediol; delta 5-Androstene-3 beta,17 beta-Diol; 5 Androstene 3,17 diol; 5 Androstene 3beta 17beta Diol; Androst 5 ene 3 beta,17 beta Diol; Androst 5 ene 3,17 diol; Delta 5 Androstenediol; delta 5 Androstene 3 beta,17 beta Diol; Androst-5-ene-3,17-diol, (3beta,17beta)-

Networked: 80 relevant articles (7 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Shimizu, Tomoharu: 7 articles (03/2007 - 08/2004)
2.	Chaudry, Irshad H: 7 articles (03/2007 - 08/2004)
3.	Choudhry, Mashkoor A: 6 articles (08/2006 - 08/2004)
4.	Bland, Kirby I: 6 articles (08/2006 - 08/2004)
5.	Loria, R M: 5 articles (09/2000 - 01/2000)
6.	Szalay, Laszlo: 4 articles (04/2006 - 08/2004)
7.	Namiki, Mikio: 3 articles (04/2010 - 01/2004)
8.	Suzuki, Takao: 3 articles (08/2006 - 04/2006)
9.	Hsieh, Ya-Ching: 3 articles (08/2006 - 08/2005)
10.	Rue, Loring W: 3 articles (04/2006 - 08/2004)

Related Diseases

1.	Infection 09/01/1997 - "In these studies the influence of androstenediol on the course of an experimental virus infection was examined. " 01/01/2000 - "Androstenediol stimulates myelopoiesis and enhances resistance to infection in gamma-irradiated mice." 06/23/1993 - "Androstenediol regulates systemic resistance against lethal infections in mice." 01/01/1992 - "Androstenediol regulates systemic resistance against lethal infections in mice." 08/03/1999 - "Androstenediol (AED) prevents neuroendocrine-mediated suppression of the immune response to an influenza viral infection."
2.	Wounds and Injuries (Trauma) 08/01/2011 - "Androstenediol represents a potential therapeutic agent after major trauma in high-risk patients." 09/01/2009 - "These findings suggest that restoration of immune regulation by androstenediol can reverse the delayed open wound contraction secondary to steroid stress." 08/01/2005 - "A recent study suggested that administration of androstenediol (Adiol) after trauma-hemorrhage (T-H) improves hepatic functions; however, the mechanism responsible for the salutary effect of Adiol remains unknown. " 07/01/2006 - "To examine the mechanism by which androstenediol improves cardiac function following trauma-hemorrhage (T-H). " 08/01/2004 - "Salutary effects of androstenediol on cardiac function and splanchnic perfusion after trauma-hemorrhage."
3.	Hemorrhage 08/01/2011 - "Traumatic hemorrhage was induced followed by androstenediol application and volume resuscitation. " 08/01/2005 - "A recent study suggested that administration of androstenediol (Adiol) after trauma-hemorrhage (T-H) improves hepatic functions; however, the mechanism responsible for the salutary effect of Adiol remains unknown. " 07/01/2006 - "To examine the mechanism by which androstenediol improves cardiac function following trauma-hemorrhage (T-H). " 08/01/2004 - "Salutary effects of androstenediol on cardiac function and splanchnic perfusion after trauma-hemorrhage." 08/01/2011 - "Androstenediol modulates the immune response after trauma-hemorrhage, cecal ligation, and cecal puncture by reducing systemic chemokine levels, which are known to direct immune cells into the tissue possibly leading to organ damage. "
4.	Sepsis (Septicemia) 04/01/2006 - "Furthermore, survival rate following T-H and subsequent sepsis was improved by androstenediol treatment. " 03/01/2014 - "Androstenediol modulates sepsis induced alterations of survival and immune functions in a murine model of sepsis." 04/01/2006 - "Since androstenediol administration following T-H attenuated cytokine production and reduced mortality in a double-hit model of T-H and sepsis, this agent appears to be a novel and useful adjunct for maintaining the immune cell functions following T-H and for decreasing the mortality rate from subsequent susceptibility to sepsis." 04/01/2006 - "Androstenediol ameliorates alterations in immune cells cytokine production capacity in a two-hit model of trauma-hemorrhage and sepsis." 08/01/2011 - "Androstenediol exerts salutary effects on chemokine response after trauma-hemorrhage and sepsis in mice."
5.	Encephalitis (Encephalitis, Rasmussen) 08/14/1998 - "Increased levels of IFN-gamma in the trigeminal ganglion correlate with protection against HSV-1-induced encephalitis following subcutaneous administration with androstenediol." 03/15/1998 - "Androstenediol antagonizes herpes simplex virus type 1-induced encephalitis through the augmentation of type I IFN production." 03/15/1998 - "Dehydroepiandrosterone and androstenediol (AED) have previously been found to protect mice from viral-induced encephalitis resulting in an increased survival rate of the animals. "

Related Drugs and Biologics

1.	Dehydroepiandrosterone (DHEA)
2.	Hormones
3.	cyclosporine metabolite M17
4.	Androgens
5.	Estrogens (Estrogen)
6.	Estradiol (Estrace)
7.	Antigens
8.	anastrozole (Arimidex)
9.	Testosterone (Sustanon)
10.	Androstenedione (4 Androstene 3,17 dione)

Related Therapies and Procedures

1.	Resuscitation
2.	Orchiectomy (Orchidectomy)
3.	Ligation
4.	Oral Administration