3,4-Methylenedioxyamphetamine (3,4 Methylenedioxyamphetamine)

An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.

Also Known As:

Networked: 14 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Abdulmonem, Waleed Al: 2 articles (03/2019 - 03/2019)
2.	Ssadh, Hussain Al: 2 articles (03/2019 - 03/2019)
3.	Debray, Marcel: 2 articles (03/2010 - 07/2008)
4.	Declèves, Xavier: 2 articles (03/2010 - 07/2008)
5.	Fonsart, Julien: 2 articles (03/2010 - 07/2008)
6.	Menet, Marie-Claude: 2 articles (03/2010 - 07/2008)
7.	Noble, Florence: 2 articles (03/2010 - 07/2008)
8.	Scherrmann, Jean-Michel: 2 articles (03/2010 - 07/2008)
9.	Guo, Jiao: 1 article (11/2021)
10.	Guo, Meili: 1 article (11/2021)

Related Diseases

1.	Cocaine-Related Disorders (Cocaine Addiction) 01/01/2017 - "This study compared the discriminative stimulus effects of mephedrone (0.32-10 mg/kg) with other prototypical drugs of abuse: cocaine (0.56-32 mg/kg), d-amphetamine (0.18-3.2 mg/kg), ketamine (1.8-18 mg/kg), phencyclidine (PCP, 1-5.6 mg/kg), heroin (1-10 mg/kg), 2,5-dimethoxy-4-iodoamphetamine (R-DOI, 0.1-1 mg/kg), Δ9-tetrahydrocannabinol (Δ9-THC 0.56-5.6 mg/kg), 3,4-methylenedioxyamphetamine (MDA, 0.32-5.6 mg/kg), methylphenidate (1-10 mg/kg), and 3,4-methylenedioxypyrovalerone (MDPV, 0.56-5.6 mg/kg). "
2.	Poisoning 04/01/1972 - "3,4-methylenedioxyamphetamine (MDA): analytical and forensic aspects of fatal poisoning." 12/02/1996 - "Distribution of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) stereoisomers in a fatal poisoning." 12/02/1996 - "This communication presents the quantitation and differential distribution of the enantiomers of 3,4-methylenedioxymethamphetamine (MDMA) and its physiologically active metabolite 3,4-methylenedioxyamphetamine (MDA) in a fatal poisoning following insufflation of MDMA, cocaine and heroin. "
3.	Breast Neoplasms (Breast Cancer) 03/01/2019 - "The expression of CD74, MIF, and CD44 molecules on the breast cancer-derived cell lines CAMA-1, 3,4-methylenedioxyamphetamine (MDA)-MB-231, and MDA-MB-43 was determined by flow cytometry, western immunoblotting, and confocal microscope. " 03/01/2019 - "The two-dimensional gel electrophoresis (2-DE) was applied in the context of the breast cancer model system to investigate the effect of interferon-gamma (IFN-γ) on the differential protein expression in breast cancer-derived cell lines CAMA-1 and 3,4-methylenedioxyamphetamine (MDA)-MB-231. "
4.	Hyperthermia 07/01/2008 - "The major metabolite in rats, 3,4-methylenedioxyamphetamine (MDA), also causes hyperthermia. " 08/01/1992 - "Hyperpyrexia induced by 3,4-methylenedioxyamphetamine ("Eve")"
5.	Substance-Related Disorders (Drug Abuse) 02/18/2002 - "Hair of young subjects (N = 36) suspected for drug abuse was analysed for morphine, codeine, heroin, 6-acetylmorphine, cocaine, methadone, amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA), and 3,4-methylenedioxyethylamphetamine (MDEA). "

Related Drugs and Biologics

1.	Heroin (Diamorphine)
2.	Dronabinol (THC)
3.	Phencyclidine (Angel Dust)
4.	Methylphenidate (Ritalin)
5.	Ketamine
6.	Dextroamphetamine (Dexedrine)
7.	Synthetic Cathinone
8.	mephedrone
9.	4-iodo-2,5-dimethoxyphenylisopropylamine (DOI-P)
10.	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)