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2-Hydroxyphenethylamine
Simple amine found in the brain. It may be modulator of sympathetic functions. Its derivatives are adrenergic agonists and antagonists. It is also used in chemical industry.
Also Known As:
2 Hydroxyphenethylamine; 2 Phenylethanolamine; beta Hydroxyphenethylamine; beta Phenylethanolamine; 2-Phenylethanolamine; Bisnorephedrine; beta-Hydroxyphenethylamine; beta-Phenylethanolamine; Benzenemethanol, alpha-(aminomethyl)-
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Biogenic Amines: 992
Biogenic Monoamines: 29
2-Hydroxyphenethylamine: 1
AT13148: 7
4-(3-(bis(beta-hydroxyphenethyl)amino)butyl)benzamide: 3
LY 79771: 2
2-(2-(dimethylamino)ethyl)-4-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenol: 1
butopamine: 1
N-(2-diethylaminoethyl)-N-(2-hydroxy-2-phenylethyl)-2,5-dichloroaniline: 1
Normoten: 1
2,3-dihydroxyphenylethanolamine
2-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenoxy)propanoic acid
2-(4-(nitrophenyl)butan-2-ylamino)-1-(4-methoxyphenyl)ethanol
3-(4-((6-((-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)amino)hexyl)oxy)butyl)benzenesulfonamide
4-(3-((2-hydroxy-2-phenethyl)amino)butyl)benzamide
cimbuterol
mapenterol
N-methylphenylethanolamine
pholedrine drug combination norfenefrine
Amino Alcohols: 20
Ethanolamines: 16
2-Hydroxyphenethylamine: 1
AT13148: 7
4-(3-(bis(beta-hydroxyphenethyl)amino)butyl)benzamide: 3
LY 79771: 2
2-(2-(dimethylamino)ethyl)-4-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenol: 1
butopamine: 1
N-(2-diethylaminoethyl)-N-(2-hydroxy-2-phenylethyl)-2,5-dichloroaniline: 1
Normoten: 1
2,3-dihydroxyphenylethanolamine
2-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenoxy)propanoic acid
2-(4-(nitrophenyl)butan-2-ylamino)-1-(4-methoxyphenyl)ethanol
3-(4-((6-((-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)amino)hexyl)oxy)butyl)benzenesulfonamide
4-(3-((2-hydroxy-2-phenethyl)amino)butyl)benzamide
cimbuterol
mapenterol
N-methylphenylethanolamine
pholedrine drug combination norfenefrine
Ethylamines: 5
Phenethylamines: 28
2-Hydroxyphenethylamine: 1
AT13148: 7
4-(3-(bis(beta-hydroxyphenethyl)amino)butyl)benzamide: 3
LY 79771: 2
2-(2-(dimethylamino)ethyl)-4-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenol: 1
butopamine: 1
N-(2-diethylaminoethyl)-N-(2-hydroxy-2-phenylethyl)-2,5-dichloroaniline: 1
Normoten: 1
2,3-dihydroxyphenylethanolamine
2-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenoxy)propanoic acid
2-(4-(nitrophenyl)butan-2-ylamino)-1-(4-methoxyphenyl)ethanol
3-(4-((6-((-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)amino)hexyl)oxy)butyl)benzenesulfonamide
4-(3-((2-hydroxy-2-phenethyl)amino)butyl)benzamide
cimbuterol
mapenterol
N-methylphenylethanolamine
pholedrine drug combination norfenefrine
Alcohols: 595
Amino Alcohols: 20
Ethanolamines: 16
2-Hydroxyphenethylamine: 1
AT13148: 7
4-(3-(bis(beta-hydroxyphenethyl)amino)butyl)benzamide: 3
LY 79771: 2
2-(2-(dimethylamino)ethyl)-4-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenol: 1
butopamine: 1
N-(2-diethylaminoethyl)-N-(2-hydroxy-2-phenylethyl)-2,5-dichloroaniline: 1
Normoten: 1
2,3-dihydroxyphenylethanolamine
2-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenoxy)propanoic acid
2-(4-(nitrophenyl)butan-2-ylamino)-1-(4-methoxyphenyl)ethanol
3-(4-((6-((-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)amino)hexyl)oxy)butyl)benzenesulfonamide
4-(3-((2-hydroxy-2-phenethyl)amino)butyl)benzamide
cimbuterol
mapenterol
N-methylphenylethanolamine
pholedrine drug combination norfenefrine
Related Diseases
1.
Dehydration (Water Stress)
06/25/1984 - "
Mechanistically significant findings presented herein include: 1) an analysis of primary deuterium isotope effects on turnover, indicating major differences in rate-determining steps for beta-chloro- and beta- hydroxyphenethylamine hydroxylation, Dkcat = 6.1 and 1.0, respectively; 2) evidence that dehydration of the gem-diol derived from oxygen- 18-labeled beta- hydroxyphenethylamine hydroxylation occurs in a random manner, attributed to dissociation of enzyme-bound gem-diol prior to alpha-aminoacetophenone formation; 3) the observation of a deuterium isotope effect for beta- chlorophenethylamine inactivation, Dkinact = 3.7, implicating C--H bond cleavage in the inactivation process; and 4) the demonstration that alpha-aminoacetophenone can replace ascorbic acid as exogenous reductant in the hydroxylation of tyramine.
"
Related Drugs and Biologics
1.
Reducing Agents
2.
Tyramine
3.
Oxygen (Dioxygen)
4.
Isotopes
5.
Enzymes
6.
Deuterium
7.
Ascorbic Acid (Vitamin C)
8.
2'-chlorophenethylamine
9.
phenacylamine