18-Hydroxycorticosterone (18 Hydroxycorticosterone)

05/01/1995 - "Some of the prohormones, such as 18-hydroxycorticosterone, are elevated in adenomas. "
01/01/1984 - "Adrenal adenoma with 18-hydroxycorticosterone excess and hypertension: a variant of aldosteronomas."
01/01/1982 - "Increased excretion of 18-hydroxycorticosterone in patients with adrenal adenomas and hypertension."
09/01/1990 - "Adrenal adenoma with excess secretion of corticosterone and 18-hydroxycorticosterone."
10/20/1985 - "Seven out of 8 patients with aldosterone-producing adenoma had above-normal serum 18-hydroxycorticosterone levels. "

01/01/1982 - "The role of 18-hydroxycorticosterone in the etiology of hypertension is still unknown."
01/01/1984 - "Adrenal adenoma with 18-hydroxycorticosterone excess and hypertension: a variant of aldosteronomas."
01/01/1982 - "Increased excretion of 18-hydroxycorticosterone in patients with adrenal adenomas and hypertension."
02/01/2002 - "The strongly enhanced 18-hydroxycorticosterone and aldosterone formation observed in the mutants provides important information on a possible role of such amino-acid replacements in the development of essential hypertension. "
03/01/1982 - "However, a few "aldosterone" and "18-hydroxycorticosterone" values for patients with essential hypertension and normal aldosterone excretion were also (moderately) increased. "

11/01/1996 - "The hormonal studies showed that the tumor produced 18-hydroxycorticosterone."
07/01/1969 - "18-Hydrocorticosterone biosynthesis in an aldosterone secreting tumor and in the surrounding nontumorous adrenal gland."
05/01/1996 - "Preoperative diagnosis was primary aldosteronism in 2, 18-hydroxycorticosterone producing adnoma in 1, pre-Cushing syndrome in 5, and nonfunctioning adrenal tumor in 1 patient. "
01/01/1993 - "Tumor tissues actively converted deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone to 18-hydroxycorticosterone and aldosterone. "
10/03/1990 - "The tumor appeared to produce autonomously cortisol as well as corticosterone, 18-hydroxycorticosterone and aldosterone. "

12/04/1982 - "Selective hypoaldosteronism is defined as diminished production of aldosterone, and sometimes also of 18-hydroxycorticosterone, with otherwise intact adrenal function. "
07/01/1985 - "Studies of renin activation and regulation of aldosterone and 18-hydroxycorticosterone biosynthesis in hyporeninemic hypoaldosteronism."
07/01/1989 - "Percent increments of plasma 18-hydroxycorticosterone and plasma aldosterone above their baseline levels after angiotensin II infusions were low or somewhat low in the patients with hyporeninemic hypoaldosteronism and low in the patients with normoreninemic hypoaldosteronism. "
07/01/1989 - "To examine the nature of adrenal abnormalities in diabetic patients with hyporeninemic and normoreninemic hypoaldosteronism, responses of plasma 18-hydroxycorticosterone and plasma aldosterone to angiotension II infusions and ACTH injection were investigated in 8 diabetic patients with hyporeninemic hypoaldosteronism and 9 diabetic patients with normoreninemic hypoaldosteronism compared to 11 control subjects. "
07/01/1989 - "In both the patients with hyporeninemic and normoreninemic hypoaldosteronism, plasma 18-hydroxycorticosterone and plasma aldosterone were low, whereas plasma cortisol and plasma corticosterone were within normal ranges. "

01/01/1985 - "The results revealed that 22 of 23 patients with aldosterone-producing adenomas had 18-hydroxycorticosterone levels greater than 100 ng/dl, and all 9 patients with idiopathic adrenal hyperplasia had plasma levels less than 100 ng/dl. "
01/01/1985 - "We found a significant relationship between serum potassium and the ratio of 18-hydroxycorticosterone to aldosterone in patients with idiopathic adrenal hyperplasia, but not in those with an aldosterone-producing adenoma. "
07/01/1983 - "Determinations of urine aldosterone, aldosterone metabolites, 18-hydroxycorticosterone and 18-hydroxydeoxycorticosterone were not applicable for differential diagnosis of the adenoma and hyperplasia forms of primary aldosteronism."
03/01/2012 - "The aim of the study was to evaluate the role of serum 18-hydroxycorticosterone (s18OHB), urinary and serum 18-hydroxycortisol (u- and s18OHF), and urinary and serum 18-oxocortisol (u- and s18oxoF) in the diagnosis of PA and its subtypes, aldosterone-producing adenoma (APA) and bilateral adrenal hyperplasia (BAH). "
10/01/1982 - "In order to systematically analyze the regulation and metabolism of steroid hormones in a case of primary aldosteronism with multiple lesions, including adenoma and nodular hyperplasia of the left adrenal gland, the amounts of 9 steroids (progesterone (P), 11-deoxycorticosterone (DOC), corticosterone (B), 18-hydroxycorticosterone (18-OH-B), aldosterone (Aldo), 17 alpha-hydroxyprogesterone (17-OH-P), 11-deoxycortisol (S), cortisol (F) and dehydroepiandrosterone sulfate (DHEAS)) contained in the plasma and in the adrenal tissues were measured. "