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XYY Karyotype

Subscribe to New Research on XYY Karyotype

Abnormal genetic constitution in males characterized by an extra Y chromosome.

Also Known As:

Karyotype, XYY; Karyotypes, XYY; XYY Karyotypes

Networked: 19 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Signs and Symptoms Pathological Conditions
- Pathologic Processes: 4357
  - Chromosome Aberrations: 9172
    - Sex Chromosome Aberrations: 78
      - XYY Karyotype: 19
        XYY syndrome 47: 68
Genetic Phenomena
- Genetic Variation
  - Mutation
    - Chromosome Aberrations: 9172
      - Sex Chromosome Aberrations: 78
        XYY Karyotype: 19
        XYY syndrome 47: 68

Related Diseases

1.	Klinefelter Syndrome (Klinefelter's Syndrome)
2.	Sex Chromosome Aberrations (Sex Chromosome Abnormality)
3.	Leg Ulcer
4.	XY Disorders of Sex Development 46 (Male Pseudohermaphroditism)
5.	Triploidy

Experts

1.	Höpfl, Reinhard: 1 article (11/2010)
2.	Gattringer, Cornelia: 1 article (11/2010)
3.	Müller, Hansgeorg: 1 article (11/2010)
4.	Scheurecker, Christine: 1 article (11/2010)
5.	Watson, William J: 1 article (10/2009)
6.	Polzin, William J: 1 article (10/2009)
7.	Cekleniak, Natalie A: 1 article (10/2009)
8.	Contag, Stephen A: 1 article (10/2009)
9.	McWeeney, Dennis T: 1 article (10/2009)
10.	Miller, Richard C: 1 article (10/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to XYY Karyotype:

1.	XXY syndromeIBA 01/01/2008 - "We found accelerated growth in early childhood in boys with 47,XXY and 47,XYY karyotypes, whereas 46,XX-males were shorter than controls. " 01/01/2008 - "In boys with 47,XXY and 47,XYY karyotypes, growth was accelerated already in childhood, compared with healthy boys. " 07/01/2004 - "Pregnancies with abnormal ultrasound findings (14/16, 87%), with 45,X or 47,XXY karyotypes (26/36, 72%), and with nonmosaic karyotypes (30/48, 63%) were terminated significantly more often than pregnancies with normal ultrasound findings (35/73, 48%; P <.01), with 47,XXX or 47,XYY karyotypes (4/12, 33%; P <.05), and with mosaic karyotypes (5/25, 20%; P =.01). " 03/01/1991 - "Seven male infants had a 47,XXY karyotype, five had a 47,XYY karyotype, and three were mosaics. " 01/01/1981 - "[Incidence of 47,XXY and 47,XYY karyotypes among the mentally ill who have committed antisocial acts]."
2.	Testosterone (Sustanon)FDA Link 05/01/1970 - "Plasma testosterone levels in males with the 47,XYY karyotype." 01/01/1987 - "Three patients with karyotype XYY who had presented with deep vein thrombosis and leg ulcers (plus pulmonary embolism in two of them) were investigated for: (1) androgens (plasma testosterone measurement, testosterone oestradiol binding globulin (TeBG) assay, GnRH 50 micrograms test), and (2) haemostasis by fibrinolysis tests (euglobulin lysis time and area, antigenic plasminogen activator assay before and after 10 min venostasis). "
3.	XYY syndrome 47IBA 10/01/1992 - "An 18-year-old male with an XYY karyotype is reported with short stature, normal intelligence and normal personality, in contrast to the XYY syndrome which can be characterized by tall stature, mental subnormality and aggressive behaviour. " 01/01/2009 - "It may occur as an independent anomaly, or as part of a syndrome with concomitant chromosomal abnormalities.XYY syndrome is a quite rare sex chromosomal abnormality with 47, XYY karyotype. "
4.	DNA ProbesIBA 02/01/1992 - "In this paper, 4 females of 46,XY and one of 47,XYY karyotype were studied by Southern blotting using 10 Y-DNA probes. "
5.	Androgen Receptors (Androgen Receptor)IBA 01/01/1985 - "A case of male pseudohermaphroditism with normal androgen receptor binding and 47,XYY karyotype."
6.	Prostaglandins D (PGD)IBA 10/01/2009 - "In triploid embryos with PGD, the frequency of the 69,XYY karyotype was 8.7% (36/413), compared with 0.74% (1/136) during the first trimester of clinical pregnancies (p = 0.002). "
7.	Plasminogen Activators (Plasminogen Activator)IBA 01/01/1987 - "Three patients with karyotype XYY who had presented with deep vein thrombosis and leg ulcers (plus pulmonary embolism in two of them) were investigated for: (1) androgens (plasma testosterone measurement, testosterone oestradiol binding globulin (TeBG) assay, GnRH 50 micrograms test), and (2) haemostasis by fibrinolysis tests (euglobulin lysis time and area, antigenic plasminogen activator assay before and after 10 min venostasis). "
8.	PeroxidasesIBA 03/01/1969 - "[Leukocyte peroxidases and the 47,XYY karyotype]."
9.	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/01/1987 - "Three patients with karyotype XYY who had presented with deep vein thrombosis and leg ulcers (plus pulmonary embolism in two of them) were investigated for: (1) androgens (plasma testosterone measurement, testosterone oestradiol binding globulin (TeBG) assay, GnRH 50 micrograms test), and (2) haemostasis by fibrinolysis tests (euglobulin lysis time and area, antigenic plasminogen activator assay before and after 10 min venostasis). "
10.	HLA Antigens (Human Leukocyte Antigens)IBA 01/01/1982 - "In one case there was evidence of chimerism as demonstrated by the presence of the XYY karyotype of the donor fetus in 20% of marrow metaphases, by the presence of double Y bodies in the peripheral blood, by the appearance of new HLA-antigens, and by red cell isoenzyme phenotypes of donor origin. "