XYY Karyotype

Abnormal genetic constitution in males characterized by an extra Y chromosome.

Also Known As:

Karyotype, XYY; Karyotypes, XYY; XYY Karyotypes

Networked: 11 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Triple X syndrome
2.	46,XY Disorder of Sex Development (Male Pseudohermaphroditism)
3.	Triploidy
4.	Venous Thrombosis (Deep-Vein Thrombosis)
5.	Pulmonary Embolism

Experts

1.	Chen, Biliang: 1 article (01/2020)
2.	Dang, Yinghui: 1 article (01/2020)
3.	Song, Tingting: 1 article (01/2020)
4.	Wan, Shanning: 1 article (01/2020)
5.	Zhang, Jianfang: 1 article (01/2020)
6.	Zheng, Yunyun: 1 article (01/2020)
7.	Cekleniak, Natalie A: 1 article (10/2009)
8.	Contag, Stephen A: 1 article (10/2009)
9.	McWeeney, Dennis T: 1 article (10/2009)
10.	Miller, Richard C: 1 article (10/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to XYY Karyotype:

1.	dichlorobis(azomycin)platinum IIIBA 01/01/2020 - "The true-positive results with 45,X, 47,XXY, 47,XXX and 47,XYY karyotypes predicted by NIPT were 14.29%, 50.00%, 66.67% and 71.43%, respectively. "
2.	Testosterone (Sustanon)FDA Link 05/01/1970 - "Plasma testosterone levels in males with the 47,XYY karyotype." 01/01/1987 - "Three patients with karyotype XYY who had presented with deep vein thrombosis and leg ulcers (plus pulmonary embolism in two of them) were investigated for: (1) androgens (plasma testosterone measurement, testosterone oestradiol binding globulin (TeBG) assay, GnRH 50 micrograms test), and (2) haemostasis by fibrinolysis tests (euglobulin lysis time and area, antigenic plasminogen activator assay before and after 10 min venostasis). "
3.	ChromatinIBA 01/01/1985 - "Chromosomal analysis showed 47, XYY karyotype; and, two Y-chromatin was revealed in cultured lymphocytes. " 01/01/1976 - "Total body potassium has been measured in chromatin positive males (Klinefelter's syndrome) and males with a 47,XYY karyotype. "
4.	DNA ProbesIBA 02/01/1992 - "In this paper, 4 females of 46,XY and one of 47,XYY karyotype were studied by Southern blotting using 10 Y-DNA probes. "
5.	Androgen Receptors (Androgen Receptor)IBA 01/01/1985 - "A case of male pseudohermaphroditism with normal androgen receptor binding and 47,XYY karyotype."
6.	Prostaglandins DIBA 10/01/2009 - "In triploid embryos with PGD, the frequency of the 69,XYY karyotype was 8.7% (36/413), compared with 0.74% (1/136) during the first trimester of clinical pregnancies (p = 0.002). "
7.	PotassiumIBA 01/01/1976 - "Total body potassium has been measured in chromatin positive males (Klinefelter's syndrome) and males with a 47,XYY karyotype. "
8.	Plasminogen Activators (Plasminogen Activator)IBA 01/01/1987 - "Three patients with karyotype XYY who had presented with deep vein thrombosis and leg ulcers (plus pulmonary embolism in two of them) were investigated for: (1) androgens (plasma testosterone measurement, testosterone oestradiol binding globulin (TeBG) assay, GnRH 50 micrograms test), and (2) haemostasis by fibrinolysis tests (euglobulin lysis time and area, antigenic plasminogen activator assay before and after 10 min venostasis). "
9.	PeroxidasesIBA 03/01/1969 - "[Leukocyte peroxidases and the 47,XYY karyotype]."
10.	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/01/1987 - "Three patients with karyotype XYY who had presented with deep vein thrombosis and leg ulcers (plus pulmonary embolism in two of them) were investigated for: (1) androgens (plasma testosterone measurement, testosterone oestradiol binding globulin (TeBG) assay, GnRH 50 micrograms test), and (2) haemostasis by fibrinolysis tests (euglobulin lysis time and area, antigenic plasminogen activator assay before and after 10 min venostasis). "