Xylans

04/15/2019 - "Antiproliferative xylan from corn cobs induces apoptosis in tumor cells."
01/01/2012 - "In a test with normal and tumor human cells, after 72 h, only HeLa tumor cell proliferation was inhibited (p < 0.05) in a dose-dependent manner by xylan, reaching saturation at around 2 mg/mL, whereas 3T3 normal cell proliferation was not affected. "
01/01/2020 - "Synthesis of Biocompatible Cholesteryl-Carboxymethyl Xylan Micelles for Tumor-Targeting Intracellular DOX Delivery."
01/01/2012 - "In vitro antioxidant, anticoagulant and antimicrobial activity and in inhibition of cancer cell proliferation by xylan extracted from corn cobs."
05/15/2018 - "In the present study, novel pH-responsive prodrug nanoparticles based on xylan-curcumin (xyl-cur) conjugate were developed to enhance the therapeutic efficacy of curcumin in cancer therapy. "

09/01/2011 - "Treatment of colitis with a commensal gut bacterium engineered to secrete human TGF-β1 under the control of dietary xylan 1."
09/01/2011 - "Resulting recombinants (BO-TGF) were tested for TGF-β production in the presence and absence of polysaccharide xylan in vitro and in vivo, and used to treat experimental murine colitis. "
09/01/2011 - "Administration of xylan in drinking water to BO-TGF-treated mice resulted in a significant clinical improvement of colitis, accelerating healing of damaged colonic epithelium, reducing inflammatory cell infiltration, reducing expression of proinflammatory cytokines, and promoting production of mucin-rich goblet cells in colonic crypts. "
08/01/2020 - "An orally administered butyrate-releasing xylan derivative reduces inflammation in dextran sulphate sodium-induced murine colitis."

10/01/2020 - "Map-based cloning revealed that WI5 encodes an active endo-1,4-β-xylanase from glycosyl dehydration family 10, which mainly functions in degrading and reorganizing cell wall xylan. "
01/24/2020 - "Moreover, the nanocomposites can also achieve the selective breaking of the C-O bonds within xylan and cellulose to form furans by dehydration. "
12/01/2015 - "Furfural was successfully produced by the dehydration of xylose and xylan using the novel catalyst in γ-valerolactone. "
08/22/2016 - "Pentose dehydration and direct transformation of xylan into furfural were performed in a water-cyclopentyl methyl ether (CPME) biphasic system under microwave irradiation. "
09/01/2013 - "Nonetheless, lignin inhibited the hydrolysis of xylan to xylose and dehydration of xylose to furfural. "

12/01/2015 - "The objective of this study was to determine the effect of two levels of inclusion of xylan oligosaccharides (XOS) extracted from corncob on growth, feed utilization, immune status and disease resistance of Mediterranean sea bass (Dicentrarchus labrax) fingerlings. "
03/27/2002 - "The Vigna unguiculata nodule and stress response transcripts present similarities to those that encode low molecular weight heat shock proteins, wound-induced proteins, disease resistance protein, and xylan endohydrolase isoenzyme, as well as different housekeeping genes. "
11/01/2017 - "Alteration of cell wall xylan acetylation caused by ESK1 impairment was accompanied by an enhanced accumulation of abscisic acid, the constitutive expression of genes encoding antibiotic peptides and enzymes involved in the biosynthesis of tryptophan-derived metabolites, and the accumulation of disease resistance-related secondary metabolites and different osmolites. "

01/01/2022 - "In the teratogenicity study, a total of 60 pregnant rats were exposed to 10, 5, and 2.5% xylan in diet, from gestation days 7 to 16, and the no-observed-adverse-effect levels (NOAEL) of xylan was determined to be 9.8 g/kg body weight. "
01/01/2022 - "In the Ames test, xylan showed no mutagenic activity on histidine dependent strains of Salmonella typhimurium at concentrations up to 5000 μg/plate; results of the in vivo mice bone marrow micronucleus test and mice sperm abnormality test indicated no significant effect on sperm morphology and micronucleus rate of polychromatic erythrocytes in mice at doses up to 5 g/kg body weight. "
07/01/2021 - "A total of 3 replicates of 20 growing gilts were blocked by initial body weight, individually housed, and assigned to 1 of 4 dietary treatments: a low-fiber control (LF) with 7.5% NDF, a 30% corn bran high-fiber control (HF; 21.9% NDF), HF + 100 mg xylanase/kg (HF + XY [Econase XT 25P; AB Vista, Marlborough, UK]) providing 16,000 birch xylan units/kg; and HF + 50 mg arabinoxylan-oligosaccharide (AXOS) product/kg (HF + AX [XOS 35A; Shandong Longlive Biotechnology, Shandong, China]) providing AXOS with 3-7 degrees of polymerization. "
12/01/2006 - "Xylose, xylobiose, xylan, and glucuronic acid showed no significant suppressive activities on mouse gastric inflammation at a dose of 100 mg/kg body weight. "