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Lutein

A carotenoid alcohol widespread in nature. It is present in egg yolk, algae, and petals of yellow flowers, among other sources.

Also Known As:

Lutein F; Lutein G; beta,epsilon-Carotene-3, 3'-Diol, (3R,3'R,6'S)-; beta,epsilon-Carotene-3,3'-diol, (3S,3'R,6'S)-; gamma Lutein; Lutein, gamma; beta,epsilon-Carotene-3,3'-diol, (3R,3'R,6'R)-

Networked: 797 relevant articles (45 outcomes, 136 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Johnson, Elizabeth J: 18 articles (09/2014 - 03/2002)
2.	Bernstein, Paul S: 16 articles (10/2014 - 10/2002)
3.	Chew, Emily Y: 14 articles (07/2015 - 12/2006)
4.	Ma, Le: 12 articles (01/2015 - 01/2009)
5.	Lin, Xiao-Ming: 11 articles (03/2015 - 01/2009)
6.	Huang, Yang-Mu: 10 articles (03/2015 - 01/2009)
7.	Zou, Zhi-Yong: 10 articles (03/2015 - 01/2009)
8.	Xu, Xian-Rong: 10 articles (03/2015 - 01/2009)
9.	Willett, Walter C: 9 articles (12/2015 - 07/2004)
10.	Gellermann, Werner: 9 articles (06/2013 - 10/2002)

Related Diseases

1.	Macular Degeneration (Age-Related Maculopathy) 10/01/2008 - "Metabolites of lutein are highly concentrated in the human macula and are known to provide protection against age-related macular degeneration. " 02/01/2013 - "Lutein and DHA supplementation is effective in increasing the MPOD and may aid in prevention of age related macular degeneration." 08/01/2011 - "Lutein has been shown to be protective against age-related macular degeneration; however, the antiinflammatory and antioxidant effects of this carotenoid in aortas are less known. " 08/01/2004 - "Lutein may be protective against diseases such as age-related macular degeneration (ARMD). " 01/01/2014 - "The conduct of this meta-analysis aimed at examining the individual role of lutein as a dietary supplement in improving conditions of age-related macular degeneration (AMD) from the data generated from randomized controlled trials (RCTs). "
2.	Cataract (Cataracts) 01/01/2003 - "Visual function in patients with age-related cataracts who received the lutein supplements improved, suggesting that a higher intake of lutein, through lutein-rich fruit and vegetables or supplements, may have beneficial effects on the visual performance of people with age-related cataracts." 12/01/2014 - "The gender-differentiated antioxidant effects of a lutein-containing supplement in the aqueous humor of patients with senile cataracts." 01/01/2009 - "Lutein prevents cataract development and progression in diabetic rats." 06/01/2008 - "Lutein may become an effective drug to prevent after-cataract." 06/01/2008 - "The effects of lutein on the growth and migration of bovine lens epithelial cells (BLECs) in vitro were observed in an attempt to find a drug that can prevent after-cataract. "
3.	Atherosclerosis 12/01/2011 - "High serum level of lutein may be protective against early atherosclerosis: the Beijing atherosclerosis study." 06/19/2001 - "The present study assessed the protective effects of the oxygenated carotenoid lutein against early atherosclerosis. " 06/19/2001 - "These epidemiological, in vitro, and mouse model findings support the hypothesis that increased dietary intake of lutein is protective against the development of early atherosclerosis." 03/01/2015 - "The main aim of this study was to investigate the effects of lutein on the alleviation of atherosclerosis and its molecular mechanisms involved in oxidative stress and lipid metabolism. " 03/01/2015 - "Epidemiological and experimental studies provide supportive evidence that lutein, a major carotenoid, may act as a chemopreventive agent against atherosclerosis, although the underlying molecular mechanisms are not well understood. "
4.	Inflammation 02/01/2015 - "Lutein derived fragments exhibit higher antioxidant and anti-inflammatory properties than lutein in lipopolysaccharide induced inflammation in rats." 01/01/2014 - "Lutein noticeably intervenes in and inhibits Hcy-mediated oxidative stress excitement and downregulates the expression of inflammation-associated informational molecules." 07/01/2012 - "Apart from beneficial effects of lutein intake on various visual function tests, recent findings show that lutein can affect immune responses and inflammation. " 04/01/2012 - "Lutein decreases oxidative stress and inflammation in liver and eyes of guinea pigs fed a hypercholesterolemic diet." 10/01/2010 - "Lutein exposure, in ovo or in the diet, reduces parameters of inflammation in the liver and spleen laying-type chicks (Gallus gallus domesticus)."
5.	Eye Diseases (Eye Disease) 01/01/2015 - "Dietary supplements containing lutein were taken by 109 subjects of whom most had eye disease (over 80%); where the average daily consumption of lutein from this source was 6.5 mg. For older people, the dietary intake of lutein from foodstuffs may be insufficient to prevent eye disease. " 01/01/2015 - "To estimate dietary intakes of lutein obtained from foodstuffs and supplements along with determining its main sources in selected groups of adults suffering from eye disease and healthy controls. " 05/01/2012 - "Lutein, a xanthophyll of a carotenoid, is anticipated as a therapeutic product to prevent human eye diseases. " 01/01/2015 - "Dietary sources of lutein in adults suffering eye disease (AMD/cataracts)." 09/01/2014 - "In addition, lutein and zeaxanthin may be protective against eye disease because they absorb damaging blue light that enters the eye. "

Related Drugs and Biologics

1.	zeaxanthin
2.	Carotenoids (Carotene)
3.	lycopene
4.	beta Carotene (Betacarotene)
5.	Retinaldehyde (Retinal)
6.	Xanthophylls
7.	cryptoxanthin (beta-cryptoxanthin)
8.	alpha-carotene
9.	Antioxidants
10.	Ascorbic Acid (Vitamin C)

Related Therapies and Procedures

1.	Capsulorhexis
2.	Phacoemulsification
3.	Drug Therapy (Chemotherapy)
4.	Mediterranean Diet
5.	Semiconductor Lasers