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Lateral Medullary Syndrome (Wallenberg's Syndrome)

Subscribe to New Research on Lateral Medullary Syndrome

INFARCTION of the dorsolateral aspect of MEDULLA OBLONGATA in the BRAIN STEM. It is caused by occlusion of the VERTEBRAL ARTERY and/or the posterior inferior cerebellar artery. Clinical manifestations vary with the size of infarction, but may include loss of pain and temperature sensation in the ipsilateral face and contralateral body below the chin; ipsilateral HORNER SYNDROME; ipsilateral ATAXIA; DYSARTHRIA; VERTIGO; nausea, hiccup; dysphagia; and VOCAL CORD PARALYSIS. (From Adams et al., Principles of Neurology, 6th ed, p801)

Also Known As:

Wallenberg's Syndrome; Syndrome, Wallenberg; Wallenberg Syndrome; Dorsolateral Medullary Syndrome; Vieseaux-Wallenberg Syndrome; Lateral Medullary Syndromes; Medullary Syndrome, Dorsolateral; Syndrome, Vieseaux-Wallenberg; Syndromes, Lateral Medullary; Vieseaux Wallenberg Syndrome; Wallenbergs Syndrome; Lateral Bulbar Syndrome; Posterior Inferior Cerebellar Artery Syndrome

Networked: 34 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Pain (Aches)
2.	Deglutition Disorders (Dysphagia)
3.	Atherosclerosis
4.	Stroke (Strokes)
5.	Trigeminal Nerve Diseases (Trigeminal Nerve Disorders)

Experts

1.	Kleiman, David A: 1 article (08/2014)
2.	Barie, Philip S: 1 article (08/2014)
3.	Miyamoto, Junichi: 1 article (03/2014)
4.	Kubo, Yousuke: 1 article (03/2014)
5.	Miyazaki, Hiroko: 1 article (03/2014)
6.	Niijima, Kyo: 1 article (03/2014)
7.	Iguchi, Fukuichiro: 1 article (03/2014)
8.	Otsuki, Taisuke: 1 article (09/2012)
9.	Yamamoto, Toshiyuki: 1 article (09/2012)
10.	Takahashi, Akio: 1 article (09/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lateral Medullary Syndrome:

1.	Myeloblastin (Proteinase 3)IBA 06/01/2000 - "Vasculitic wallenberg syndrome with detection of anti-proteinase 3 antibodies in the cerebrospinal fluid of a patient with severe Wegener's granulomatosis and only mild kidney involvement."
2.	Technetium Tc 99m Exametazime (Ceretec)FDA Link 06/01/1988 - "Regional cerebellar perfusion was imaged using technetium Tc 99m hexamethylpropylene amine oxime and single photon emission computed tomography (HM-PAO-SPECT) in a patient with chronic left lateral medullary syndrome with contralateral weakness due to traumatically induced thrombosis of the left vertebral artery. "
3.	Phenytoin (Dilantin)FDA LinkGeneric 10/21/1974 - "Letter: Diphenylhydantoin in the Wallenberg syndrome."
4.	Carbon MonoxideIBA 05/06/1957 - "[Coronary disease with co-existing lateral bulbar Babinski-Nageotte-Wallenberg syndrome]."
5.	Baclofen FDA LinkGeneric 03/01/1997 - "We recommend consideration of baclofen for the treatment of persistent hiccups after lateral medullary syndrome because of its desirable side effects and reported success rate compared with other drugs used to treat chronic hiccups."
6.	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/01/2010 - "The patient had been taking aspirin for 3 years after suffering from ischemic Wallenberg's syndrome with left paresthesia as a residual symptom. "
7.	AntibodiesIBA 06/01/2000 - "Vasculitic wallenberg syndrome with detection of anti-proteinase 3 antibodies in the cerebrospinal fluid of a patient with severe Wegener's granulomatosis and only mild kidney involvement."
8.	Anti-Idiotypic AntibodiesIBA 09/01/2009 - "Lateral medullary syndrome with anti-neuronal antibodies (anti-Ta/Ma2) in primary Sjogren's syndrome."
9.	alpha-Fetoproteins (AFP)IBA 06/01/2007 - "21 (51.2%) were considered AFP and 20 (48.8%) (SFP) received the following diagnosis: 8 (40.0%) had temporomandibular disorders (TMD); 3 (15.0%) had TMD associated to systemic disease (fibromyalgia, systemic erythematosus lupus); 4 (20.0%) had neuropathy after ear, nose and throat (ENT) surgery for petroclival tumor; 2 (10.0%) had Wallenberg syndrome; 1 (5.0%) had intracranial tumor; 1 (5.0%) had oral cancer (epidermoid carcinoma), and 1 (5.0%) had burning mouth syndrome (BMS) associated to fibromyalgia. "
10.	Adrenal Cortex Hormones (Corticosteroids)IBA 09/01/2012 - "Here we report an extremely rare case of Behçet syndrome (BS) that showed acute onset of Wallenberg syndrome and was treated successfully by corticosteroids. "

Therapies and Procedures

1.	Chiropractic Manipulation 09/01/2004 - "[Wallenberg's syndrome secondary to dissection of the vertebral artery caused by chiropractic manipulation]." 11/01/2003 - "We describe the case of a young patient who suffered from incomplete Wallenberg s syndrome a few hours after a single session of cervical chiropractic manipulation, and we also show the resonance images that were used to support the diagnosis. " 11/01/2003 - "[Wallenberg's syndrome secondary to dissection of the vertebral artery caused by chiropractic manipulation]." 03/01/1956 - "Posterior inferior cerebellar artery syndrome of Wallenberg after chiropractic manipulation."
2.	Catheters 06/01/2000 - "[Swallowing rehabilitation using balloon catheter treatment evaluated by videofluorography in an elderly patient with Wallenberg's syndrome]." 03/01/2014 - "[Successful treatment of dysphagia due to Wallenberg syndrome using intermittent air stretching method with balloon catheter: a case report]."
3.	Lasers (Laser) 10/01/2005 - "We examined LEPs and laser-induced prepulse inhibition of the blink reflex in seven patients with Wallenberg's syndrome within a month after the infarct. " 10/01/2005 - "Spinothalamic tract lesions in patients with Wallenberg's syndrome can be demonstrated by abnormalities in the laser evoked potentials (LEPs) to stimulation of the affected side. " 10/01/2005 - "Laser evoked potentials and prepulse inhibition of the blink reflex in patients with Wallenberg's syndrome." 10/01/2003 - "To investigate trigeminal C-fibre function, we directed laser pulses to the facial skin and studied sensory perception and scalp evoked potentials related to Adelta- or C-fibre activation in healthy humans and patients--one having a bilateral facial palsy, two a trigeminal neuropathy, and two a Wallenberg syndrome. "
4.	Endovascular Procedures 09/01/2010 - "Risk factors that varied with favorable versus unfavorable outcomes were: preoperative Hunt-Hess, World Federation of Neurological Surgeons scale, presence of hydrocephalus, presence of lateral medullary syndrome, presence of low cranial nerve palsy, rebleeding, time of endovascular procedures, and time from admission to procedure. "
5.	Sternotomy 04/01/1998 - "In this report, we describe a patient who underwent coronary artery bypass grafting (CABG) through bilateral thoracotomy and distal median sternotomy, because he had received terminal tracheotomy as a treatment to prevent aspiration pneumonia due to Wallenberg's syndrome. "