Voice Disorders (Voice Disturbances)

Pathological processes that affect voice production, usually involving VOCAL CORDS and the LARYNGEAL MUCOSA. Voice disorders can be caused by organic (anatomical), or functional (emotional or psychological) factors leading to DYSPHONIA; APHONIA; and defects in VOICE QUALITY, loudness, and pitch.

Also Known As:

Networked: 131 relevant articles (4 outcomes, 15 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Polyps
2.	Hoarseness
3.	Dysphonia (Spastic Dysphonia)
4.	Deglutition Disorders (Dysphagia)
5.	Cleft Lip (Harelip)

Experts

1.	Roy, Nelson: 5 articles (01/2014 - 06/2003)
2.	Smith, Marshall E: 3 articles (05/2013 - 01/2007)
3.	Gray, Steven D: 3 articles (04/2004 - 07/2002)
4.	Yamamoto, Masahiko: 2 articles (12/2015 - 08/2015)
5.	Ohdake, Reiko: 2 articles (12/2015 - 08/2015)
6.	Sobue, Gen: 2 articles (12/2015 - 08/2015)
7.	Tanaka, Yasuhiro: 2 articles (12/2015 - 08/2015)
8.	Hara, Kazuhiro: 2 articles (12/2015 - 08/2015)
9.	Watanabe, Hirohisa: 2 articles (12/2015 - 08/2015)
10.	Ito, Mizuki: 2 articles (12/2015 - 08/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Voice Disorders:

1.	Vitamin A (Retinol)FDA LinkGeneric 07/01/2011 - "CoQ10-ter and Vitamin A risulted effective in treatment of patients with functional voice disorders (caused by vocal "malmenage" or "surmenage")." 07/01/2011 - "Aim of this study was to evaluate the effectivness of Coenzyme Q-Ter and Vitamin A in functional voice disorders. "
2.	Botulinum Toxins (Botulinum Toxin)IBA 11/28/1990 - "Treatment of speech and voice disorders with botulinum toxin." 11/01/1992 - "Because the thyroarytenoid was affected in all the patients studied, botulinum toxin injections may be beneficial in treatment of this voice disorder." 11/01/2013 - "Voice disorders in the workplace: productivity in spasmodic dysphonia and the impact of botulinum toxin." 01/01/2004 - "The use of botulinum toxin for the treatment of spasmodic dysphonia is currently the treatment of choice for management of this neurological voice disorder. " 01/01/2001 - "Spasmodic dysphonia is a rare voice disorder that is most successfully treated by injection of botulinum toxin (i.e., BOTOX) into the affected laryngeal muscles. "
3.	Calcium Carbonate (Limestone)FDA Link 10/01/2012 - "The purpose of this study was to investigate previously described vocal risk factors as well as to identify new risk factors related to both the personal life of the teacher (fluid intake, voice-demanding activities, family history of voice disorders, and children at home) and to environmental factors (temperature changes, chalk use, presence of curtains, carpet, or air-conditioning, acoustics in the classroom, and noise in and outside the classroom). " 06/01/2011 - "The study concluded that teachers, 40 years old and over, with a family history of dysphonia, working over 20 hours weekly, and teaching in classrooms with chalk dust are more likely to develop voice disorders than others."
4.	UbiquinoneIBA 07/01/2011 - "Aim of this study was to evaluate the effectivness of Coenzyme Q-Ter and Vitamin A in functional voice disorders. "
5.	Sodium Glutamate (Accent)IBA 09/01/2013 - "Children with nonorganic voice disorders (NVDs) are treated mainly using direct voice therapy techniques such as the accent method or glottal attack changes and indirect methods such as vocal hygiene and voice education. " 06/01/1994 - "Ten patients who were referred to a speech pathologist for functional voice disorders were treated with voice therapy using the accent method. " 06/01/1977 - "In an earlier paper [HNO 25, 102 (1977)], the accent-method for the treatment of voice disorders has been described in detail. " 03/01/1977 - "One of the best known methods in northern Europe for the treatment of voice disorders is the "accent-method", which was devised by Svend Smith in Denmark. " 03/01/1977 - "[Observations on the accent-method of Smith in the management of speech and voice disturbances. "
6.	HormonesIBA 01/01/2013 - "A majority (88%) had a history of feminizing hormone treatment and 28% presented with a voice disorder separate from gender presentation concerns. " 07/01/1989 - "[Hormone-induced voice disorders]." 01/01/1968 - "[Hormone induced voice disorders]." 12/09/1963 - "[ON DATA ON HORMONE-RELATED VOICE DISORDERS IN WOMEN (WITH FILM)]." 01/03/1959 - "[Treatment of voice disorders in women after hormone therapy]."
7.	Erythromycin (Erycette)FDA LinkGeneric 01/01/2015 - "Erythromycin could reduce voice disturbance at one week and cough at two weeks when measured subjectively. " 01/01/2013 - "Erythromycin could reduce voice disturbance at one week and cough at two weeks when measured subjectively. " 01/01/2007 - "Erythromycin could reduce voice disturbance at one week and cough at two weeks when measured subjectively. " 01/01/2005 - "Erythromycin could reduce voice disturbance at one week and cough at two weeks when measured subjectively. " 01/01/1992 - "As compared to controls, erythromycin treated patients reported significantly lower scores of subjective voice disturbance after 1 week and cough after 2 weeks. "
8.	SmokeIBA 01/01/2010 - "In 2008, there were 78 such programs in the country, the most popular of them were those focused on occupational voice disorders and tobacco smoke). " 05/01/2005 - "The prevalence of voice disorders among La Rioja Teachers was 57%: 20.3% for organic lesions [nodular lesions (14%), polyps (2%), submucous suffusions (1.4%), edema Reinke (1.2%) Sulcus (0.4%), scalp (0.6%), leucoplasia (0.2%) vocal cord paralysis (0.2%)] 8.1% for chronic laryngitis [not specific (2.8%), smoke (3.9%) gastroe-sofageal reflux (2.5%)] and 29% for functional lesions [hyperfunctional dysphonia (7.5%) hypofunctional dysphonia (0.4%) vocal overefforts (18%) hyperplasia false cords (2.8)]. " 07/01/2008 - "We find a significant risk of suffering voice disorders in teachers who smoke daily (OR: 2.31, CI: 1.58-3.37) and who drink several cups of coffee or tea (OR: 1.87, CI: 1.36-2.56). "
9.	Carbon MonoxideIBA 04/01/2011 - "Voice disorders due to laryngeal insufficiency were common in children with dysarthria and co-occurred with CAS. " 11/01/1989 - "A psychogenic voice disorder co-occurred or evolved with the symptoms and signs of unilateral superior laryngeal nerve paresis. "
10.	onabotulinumtoxinA (Botox)FDA Link 10/01/2001 - "After establishment of a normal to near-normal voice with Botox injections, these complaints were reduced to normal levels--a finding suggesting these phenomena to be secondary to the voice disorder. " 01/01/2001 - "Spasmodic dysphonia is a rare voice disorder that is most successfully treated by injection of botulinum toxin (i.e., BOTOX) into the affected laryngeal muscles. "

Therapies and Procedures

1.	Laryngoscopes 04/01/2004 - "During a six month period, one hundred patients presenting with the primary complaint of hoarseness, in the out- patients department of otolaryngology at Safdarjung Hospital New Delhi were taken up fot the study Fach patient after being subjected to a detailed history- taking and examination, including a Fibreoptic Laryngoscopy was then put into one of ten categories on the basis of the ultimate diagnosis Functional voice disorders, forming the largest category with 51%, included lesions such as vocal nodules and polyps, which are secondary to vocal abuse A detailed study of the various types of functional voice disorders along with factors such as male female ratio and associated contributory factors was done the efficacy of the Fibreoptic laryngoscope as a diagnostic tool was also assessed."
2.	Psychology Biofeedback (Biofeedback) 12/01/1993 - "Results suggest that interdisciplinary, collaborative efforts using biofeedback and voice therapy can prove beneficial in the treatment of hyperfunctional voice disorders." 01/01/2012 - "Biofeedback on voice use in call center agents in order to prevent occupational voice disorders." 03/01/2004 - "A relatively new management strategy for the treatment of voice disorders is the use of laryngeal (LB) and velopharyngeal biofeedback (VB). " 12/01/1993 - "The interdisciplinary approach to the treatment of this voice disorder involved the combined use of traditional voice therapy techniques and EMG biofeedback procedures together with cognitive behavioral therapy. " 12/01/1993 - "The purpose of this article is to describe the treatment of a 45-year-old male with a hyperfunctional voice disorder by a biofeedback therapist and a speech-language pathologist. "
3.	Injections 11/01/1992 - "Because the thyroarytenoid was affected in all the patients studied, botulinum toxin injections may be beneficial in treatment of this voice disorder." 10/01/2001 - "After establishment of a normal to near-normal voice with Botox injections, these complaints were reduced to normal levels--a finding suggesting these phenomena to be secondary to the voice disorder. "
4.	Day Care (Partial Hospitalization) 01/01/2002 - "The purpose of this study was to measure some of the risk factors for voice disorders of day care center teachers and of a control group (nurses); these were speaking times and speech levels. " 09/01/2001 - "The prevalence of voice disorders among day care center teachers compared with nurses: a questionnaire and clinical study." 01/01/2002 - "Several risk factors may increase voice disorder prevalence of day care center teachers. " 01/01/2002 - "Day care center teachers suffer from voice disorders more often than nurses do. " 09/01/2001 - "The results prove voice disorders to be more frequent among day care center teachers than among control group subjects, and also that the main cause for this may be a higher vocal loading among day care center teachers than among control group subjects."
5.	Voice Training 03/01/2011 - "In total, 10 studies that investigated the impact of a voice training intervention on the vocal quality of professional voice users as a potential prevention strategy for voice disorders were selected for this review. " 03/01/2015 - "The research showed that 16.4% had suffered some voice disorder and a remarkable percentage had never received any kind of voice training. " 05/01/2013 - "Data collected included initial medical screening with laryngologist, referral to speech-language pathologist (SLP) specializing in voice disorders among singers, and adjunctive voice training with voice teacher trained in vocology (singing voice specialist or SVS). " 04/01/2011 - "To explore the effectiveness of voice training on professional voice users with voice disorders. " 04/01/2011 - "[Effectiveness of voice training for professional voice users with voice disorders]."