Vitamin B Deficiency

A condition due to deficiency in any member of the VITAMIN B COMPLEX. These B vitamins are water-soluble and must be obtained from the diet because they are easily lost in the urine. Unlike the lipid-soluble vitamins, they cannot be stored in the body fat.

Also Known As:

Networked: 65 relevant articles (2 outcomes, 7 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Infections
2.	Nervous System Diseases (Neurological Disorders)
3.	Hypocalcemia
4.	Hypertension (High Blood Pressure)
5.	Hyperhomocysteinemia

Experts

1.	Herrmann, Wolfgang: 2 articles (03/2013 - 05/2008)
2.	Gramer, Gwendolyn: 1 article (06/2021)
3.	Hennermann, Julia B: 1 article (06/2021)
4.	Hoffmann, Georg F: 1 article (06/2021)
5.	Al Dhaheri, Ayesha S: 1 article (04/2021)
6.	Al Mansoori, Amna: 1 article (04/2021)
7.	Ali, Habiba I: 1 article (04/2021)
8.	Apostolopoulos, Vasso: 1 article (04/2021)
9.	Bosevski, Marijan: 1 article (04/2021)
10.	Cheikh Ismail, Leila: 1 article (04/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Vitamin B Deficiency:

1.	VitaminsIBA 06/01/2011 - "The study indicates a high risk of vitamin B deficiencies in the elderly and suggests that deficiencies of vitamins B6 and B12 are associated with length of stay. " 01/17/2008 - "Eight vitamin infections over four weeks led to a clear improvement in the mood and vitality of patients with symptoms of intracellular vitamin B deficiency." 01/01/2019 - "Vitamin B deficiency and elevated total plasma homocysteine have been associated with cognitive impairment and dementia in later life, although it is unknown if treatment with these vitamins improves cognitive outcomes. " 07/01/1945 - "The Role Of Adenine and Pantothenic Acid In the Correction Of Neuromuscular Disorders Of Vitamin B Deficiency Partially Compensated By the Addition Of Vitamins B1, B2, and P.P."
2.	Vitamin B Complex (B Vitamins)IBA 01/01/2009 - "Vitamin B deficiency causes many diseases, which may be improved by vitamin B supplementation. " 04/11/2023 - "Our article provides a review of updated evidence on the biochemical and physiological properties of the vitamin B sub-forms in normal states, and how vitamin B deficiency and defects in their metabolic pathways may influence CKD/DKD pathophysiology, and in reverse how CKD/DKD progression may affect vitamin B metabolism. " 08/01/2001 - "Does a single vitamin B-supplementation induce functional vitamin B-deficiency?" 01/01/1927 - "The Physiological Rôle of Vitamin B: Part V. The Relation of Inanition to Vitamin B Deficiency in Pigeons." 11/26/2022 - "MR analysis identified an association between higher genetically predicted vitamin B12 status and lower risk of vitamin B deficiency (including all B vitamin deficiencies), serving as a positive control outcome. "
3.	HomocysteineIBA 01/10/2008 - "Elevated homocysteine levels resulting from vitamin B deficiencies have been hypothesized to contribute to functional decline. " 02/01/2007 - "Gestational vitamin B deficiency leads to homocysteine-associated brain apoptosis and alters neurobehavioral development in rats." 01/01/2022 - "Plasma homocysteine is a marker of vitamin B deficiency and has been associated with cognitive impairment. " 04/20/2021 - "In addition, vitamin B deficiency can disrupt the methylation of homocysteine, leading to hyperhomocysteinemia. " 01/01/2007 - "Increased levels of homocysteine (HCY) and vitamin B deficiency, obesity and central adiposity in midlife are independent risk factors for the development of dementia. "
4.	Folic Acid (Vitamin M)FDA LinkGeneric 01/01/2006 - "Folic acid and other vitamin B deficiencies and elevated total plasma homocysteine levels are associated with increased cardiovascular risk in geriatric patients, but recent studies have questioned the importance of these risk factors in older people. " 03/01/2009 - "However, along with conventional RAS clinical management, iron, folic acid, vitamin B deficiencies, and nutritional intolerance must be considered. " 01/01/2000 - "In patients with normal angiogram, vitamin B12 and folate levels were significantly higher compared with the other groups (p < 0.05 and p < 0.001, respectively) showing that vitamin B deficiency was not involved in the hyperhomocysteinemia. " 01/01/2021 - "Deficiency of pyridoxine is usually found in association with other vitamin B deficiencies such as folate (vitamin B9) and cobalamin (vitamin B12). " 05/01/1999 - "The frequency of vitamin B deficiency in serum of longeval subjects compared to seniors was as follows: vitamin B6 43% vs. 22%, vitamin B12 20% vs. 8%, and folic acid 1% in both groups. "
5.	Thiamine (Aneurin)FDA Link 10/01/2020 - "Vitamin B deficiencies were frequent (74%) including at least 47% of cases with deficiency in Vitamin B1. " 01/01/1955 - "[Vitamin B deficiency, thiamine and dissociation reaction; chronaximetric measurements]." 10/31/1956 - "[Study of auriculo-ventricular & intraventricular conduction in experimental vitamin B deficiency in rats (thiamine, riboflavine, pyridoxine)]." 10/17/2016 - "A number of cases around the world have been reported where animals were found dead or dying with symptoms resembling a thiamine (vitamin B) deficiency, and for some of these, a link to pollutants has been suggested. "
6.	Pyridoxine (Pyridoxin)FDA LinkGeneric 10/31/1956 - "[Study of auriculo-ventricular & intraventricular conduction in experimental vitamin B deficiency in rats (thiamine, riboflavine, pyridoxine)]." 01/01/2021 - "Deficiency of pyridoxine is usually found in association with other vitamin B deficiencies such as folate (vitamin B9) and cobalamin (vitamin B12). "
7.	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/30/2023 - "This study investigates the intricate mechanisms underlying PPI's effects, focusing on potential pathways contributing to hypertension, such as endothelial dysfunction, disruption of nitric oxide bioavailability, vitamin B deficiency, hypocalcemia, and hypomagnesemia. "
8.	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 06/01/2021 - "The differential diagnosis of maternally caused vitamin B deficiencies should be considered in children with abnormal NBS results for MADD, especially in the presence of normal molecular genetic analysis or in case of associated findings of other maternal vitamin B deficiencies like vitamin B12 or folic acid deficiency." 07/01/2023 - "Notably, vitamin B deficiency, particularly in vitamin B9 and vitamin B12, emerges as a significant factor in childhood hyperhomocysteinemia, initiating the development of subclinical atherosclerosis in early life. " 11/26/2022 - "MR analysis identified an association between higher genetically predicted vitamin B12 status and lower risk of vitamin B deficiency (including all B vitamin deficiencies), serving as a positive control outcome. " 06/01/2021 - "As both vitamin B12 and riboflavin have similar food sources we postulate that in these cases positive NBS for MADD was caused by combined maternal vitamin B deficiencies. " 01/01/2000 - "In patients with normal angiogram, vitamin B12 and folate levels were significantly higher compared with the other groups (p < 0.05 and p < 0.001, respectively) showing that vitamin B deficiency was not involved in the hyperhomocysteinemia. "
9.	Proteins (Proteins, Gene)FDA Link 06/01/2003 - "We carried out this work with the purpose of studying the effects of protein and vitamin B deficiency on the morphologic and quantitative aspects of the myenteric plexus of the descending colon of adult Rattus norvegicus. " 06/01/2003 - "Effect of protein and vitamin B deficiency on the morpho-quantitative aspects of the myenteric plexus of the descending colon of adult rats." 09/01/2001 - "Effects of protein and vitamin B deficiency on blood parameters and myenteric neurons of the colon of rats." 10/15/1976 - "It was interesting to observe that protein and vitamin B deficiency in the diet shortened the tumour induction period in Swiss strain mice." 04/01/1954 - "[Vitamin B deficiency and mixed protein diet]."
10.	IronIBA 04/01/1983 - "Both iron and vitamin B deficiencies are easy to treat with supplements, but the clinician must make a careful search for the cause of the deficiency. " 01/01/1952 - "Glossitis and epithelial atrophy in old age; its relation to iron and vitamin B deficiency." 03/01/2009 - "However, along with conventional RAS clinical management, iron, folic acid, vitamin B deficiencies, and nutritional intolerance must be considered. "

Therapies and Procedures

1.	Therapeutics 05/10/1963 - "[Recent biochemical studies on the diagnosis and therapy of vitamin B deficiency states]." 02/16/1963 - "[Recent biochemical studies on the diagnosis and therapy of vitamin B deficiency states]." 05/11/1957 - "[Microbiological investigation on vitamin B deficiency following antibiotic therapy]." 03/01/1949 - "A clinical report of three cases of vitamin B deficiency occurring during streptomycin therapy." 01/01/2016 - "A potential contribution of bipolar disorder and metabolic encephalopathies due to severe hypothyroidism, glucocorticoid treatment, accelerated thyroid hormone replacement therapy, or vitamin B deficiency is critically discussed. "
2.	Bariatric Surgery 01/01/2017 - "The aim of this study was to assess the incidence, clinical presentation, and outcomes of neurologic disorders secondary to vitamin B deficiencies following bariatric surgery. " 01/01/2017 - "Nutritional neurologic disorders secondary to vitamin B deficiency are relatively uncommon after bariatric surgery. " 01/01/2017 - "Neurologic Manifestations of Vitamin B Deficiency after Bariatric Surgery." 10/01/2012 - "The increasing number of bariatric surgeries has revealed an increasing number of complications related to this procedure, including Wernicke´s encephalopathy and vitamin B deficiency polyneuropathies. "
3.	Length of Stay 06/01/2011 - "The study indicates a high risk of vitamin B deficiencies in the elderly and suggests that deficiencies of vitamins B6 and B12 are associated with length of stay. "
4.	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/01/2017 - "In total, 47 (0.7%) bariatric surgical patients (Roux-en-Y gastric bypass n = 36, sleeve gastrectomy n = 9, and duodenal switch n = 2) developed neurologic manifestations secondary to vitamin B deficiencies. "
5.	Gastrectomy 01/01/2017 - "In total, 47 (0.7%) bariatric surgical patients (Roux-en-Y gastric bypass n = 36, sleeve gastrectomy n = 9, and duodenal switch n = 2) developed neurologic manifestations secondary to vitamin B deficiencies. "