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Viral Matrix Proteins

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Proteins associated with the inner surface of the lipid bilayer of the viral envelope. These proteins have been implicated in control of viral transcription and may possibly serve as the "glue" that binds the nucleocapsid to the appropriate membrane site during viral budding from the host cell.

Also Known As:

Granulin Matrix Proteins; Viral M Protein; Viral Membrane Proteins; M Protein, Viral; M Proteins, Viral; Matrix Proteins, Granulin; Matrix Proteins, Viral; Protein, Viral M; Proteins, Granulin Matrix; Proteins, Viral M; Proteins, Viral Matrix; Proteins, Viral Membrane; Membrane Proteins, Viral; Viral M Proteins

Networked: 16 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Viral Proteins: 1642
    - Viral Structural Proteins: 145
      - Viral Envelope Proteins: 63
        Viral Matrix Proteins: 16
        Epstein-Barr virus EBV-associated membrane antigen: 46
        cytomegalovirus matrix protein 65kDa: 17
        influenza matrix peptide (58-66): 14
        Influenza A virus M2 protein: 5
        Coronavirus M protein: 4
        Vesicular stomatitis virus M protein: 3
        human cytomegalovirus pp67 protein: 2
        influenza virus membrane protein (58-66): 2
        Influenza C virus CM2 protein: 1
        influenza virus M-protein: 1
        Sendai virus M protein: 1
        vaccinia virus B5 protein: 1
        Bacteriophage M2 sp6.6 protein
        bacteriophage phi6 protein P9
        bovine leukemia virus protein p10
        chandipura virus M protein
        Choristoneura fumiferana nuclear polyhedrosis virus GP67 protein
        cytomegalovirus 64kDa major structural protein
        Cytomegalovirus pp150 protein
        Ebola virus transmembrane glycoprotein
        Epstein-Barr virus GP 300-350
        equine arteritis virus M protein
        Human cytomegalovirus IE1-pp65 recombinant protein
        Human herpesvirus 2 UL49A protein
        human herpesvirus 4 BNLF21 protein
        infectious salmon anaemia virus M1 protein
        infectious salmon anaemia virus M2 protein
        Influenza A virus M1 protein
        influenza B virus M1 matrix protein
        influenza matrix peptide MAT(17-31)
        Lassa virus protein Z
        mumps virus matrix protein
        murine cytomegalovirus M82 protein
        murine cytomegalovirus M83 protein
        murine leukemia virus protein p2E
        nuclear polyhedrosis virus p39 protein
        porcine reproductive and respiratory syndrome virus M protein
        pp 64-69 cytomegalovirus matrix protein
        Rinderpest virus matrixprotein
        Rous sarcoma virus MA protein
        SARS virus sars7a protein
        simian immunodeficiency virus matrix protein p17
        spring viremia carp virus M protein
        SSPE virus M protein
        Tobacco vein mottling virus TVMV 34k protein
        Tobacco vein mottling virus TVMV 42k protein
        turkey rhinotracheitis pneumovirus M2 protein
        vaccinia virus H2 protein
        variola virus SPICE protein
        Viral hemorrhagic septicemia virus M2 protein
        virus VP40 protein

Experts

1.	Enquist, L W: 2 articles (10/2008 - 08/2001)
2.	Lau, Sheung-Yee Kathy: 1 article (03/2015)
3.	Crump, Colin M: 1 article (03/2015)
4.	Rajani, Karishma R: 1 article (11/2013)
5.	Ahmed, Maryam: 1 article (11/2013)
6.	Hiltbold, Elizabeth M: 1 article (11/2013)
7.	Westcott, Marlena M: 1 article (11/2013)
8.	Lyles, Douglas S: 1 article (11/2013)
9.	Smedberg, Jason R: 1 article (11/2013)
10.	Kratchmarov, Radomir: 1 article (09/2013)

Related Diseases

1.	Infection 10/01/2008 - "We report that Us9-EGFP does not promote anterograde spread of infection and may disrupt packing of viral membrane proteins in lipid rafts, an essential step for Us9-mediated axonal sorting." 03/01/2008 - "As the infection progressed, they were enveloped and colocalized with the viral membrane proteins. " 11/01/2001 - "In conclusion, our data suggest that infection by VSV and specifically overexpression of the viral M-protein interferes with an important signaling pathway necessary for triggering antiviral and inflammatory responses." 08/20/2001 - "At least three viral membrane proteins (gE, gI, and Us9) are necessary for the spread of infection from presynaptic to postsynaptic neurons (anterograde spread) in infected rodents. " 11/01/2013 - "Preservation of dendritic cell function during vesicular stomatitis virus infection reflects both intrinsic and acquired mechanisms of resistance to suppression of host gene expression by viral M protein."
2.	Subacute Sclerosing Panencephalitis (SSPE) 11/01/1985 - "In SSPE brain, the viral M-protein defect is not a deletion of the M gene, but rather a block in gene expression." 01/01/1980 - "The differences in membrane labeling seem to reflect differences in the expression of viral membrane proteins by the various SSPE and measles virus strains." 06/01/1990 - "Rat glioma C6 cells persistently infected with measles subacute sclerosing panencephalitis (SSPE) virus (C6/SSPE) express the viral membrane proteins haemagglutinin (HA) and F on their cell surface as well as the intracellular proteins N, P and M. "
3.	Vesicular Stomatitis 10/30/1983 - "Identification of a new protein present in vesicular stomatitis virus-infected Chinese hamster ovary cells as a degradation product of viral M protein." 11/01/2013 - "Preservation of dendritic cell function during vesicular stomatitis virus infection reflects both intrinsic and acquired mechanisms of resistance to suppression of host gene expression by viral M protein."
4.	Vaccinia 10/24/2000 - "Remarkably, the cysteine-containing domains of the E10R and L1R viral membrane proteins and the glutaredoxin are in the cytoplasm, in which assembly of vaccinia virions occurs, rather than in the oxidizing environment of the endoplasmic reticulum. "
5.	Measles 06/01/1990 - "Rat glioma C6 cells persistently infected with measles subacute sclerosing panencephalitis (SSPE) virus (C6/SSPE) express the viral membrane proteins haemagglutinin (HA) and F on their cell surface as well as the intracellular proteins N, P and M. "

Related Drugs and Biologics

1.	Antibodies
2.	Glycoproteins (Glycoprotein)
3.	Glutaredoxins
4.	Proteins (Proteins, Gene)
5.	Membrane Proteins (Integral Membrane Proteins)
6.	Cysteine (L-Cysteine)