Vinyl Chloride (Chloroethylene)

A gas that has been used as an aerosol propellant and is the starting material for polyvinyl resins. Toxicity studies have shown various adverse effects, particularly the occurrence of liver neoplasms.

Also Known As:

Networked: 425 relevant articles (2 outcomes, 37 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Boffetta, Paolo: 5 articles (08/2013 - 06/2003)
2.	Wang, Jung-Der: 5 articles (02/2011 - 02/2002)
3.	Ruckart, Perri Zeitz: 4 articles (01/2015 - 01/2013)
4.	Maslia, Morris: 4 articles (01/2015 - 01/2013)
5.	Bove, Frank J: 4 articles (01/2015 - 01/2013)
6.	Fedeli, Ugo: 4 articles (08/2013 - 08/2004)
7.	Mastrangelo, Giuseppe: 4 articles (08/2013 - 08/2004)
8.	Xia, Zhao-Lin: 4 articles (12/2011 - 10/2005)
9.	Cheng, Tsun-Jen: 4 articles (02/2011 - 04/2003)
10.	La Vecchia, Carlo: 3 articles (08/2013 - 12/2009)

Related Diseases

1.	Acquired Immunodeficiency Syndrome (AIDS) 01/01/1980 - "The contamination of dietary fats and oils can have various origins: contamination of the raw materials that could not be eliminated by the industrial process; refining completely eliminates this type of contamination; contamination with one of the processing aids can occur if the process is not properly conducted; contamination with packaging materials will increase with the storage duration of the finished product (in the case of vinyl chloride monomer and styrene contamination); only the strict control and adequate choice of the materials and packaging conditions will allow complete elimination of this contamination type. " 04/01/2001 - "Beside the well investigated role of the human immunodeficiency virus 1 (HIV-1) and the human herpesvirus 8 (HHV-8) in the tumorigenesis of AIDS-related Kaposi's sarcoma and several inherited disorders, considerable evidence support a relationship between occupational chemicals as vinyl chloride, phenoxyacetic acid herbicides, chlorphenols, dioxin, medicinal measures as Thorotrast exposure and therapeutic irradiation, and the development of soft tissue sarcoma. "
2.	Larva Migrans (Cutaneous Larva Migrans) 05/01/1951 - "[Case of larva migrans rapidly cured with chloroethylene]."
3.	Hemangiosarcoma (Angiosarcoma) 07/01/1998 - "This study offers new evidence of the occurrence of vinyl-chloride-induced angiosarcomas outside the liver and confirms observations that have previously been published in case reports. " 05/01/1997 - "Vinyl chloride causes angiosarcoma of the liver, but a large, multi-country study provided no clear evidence that other sites are affected." 01/01/1997 - "In the period of study, there were no confirmed non-occupationally exposed cases of angiosarcoma among residents living near a vinyl chloride site in Great Britain." 10/01/1981 - "This study demonstrated that older adult animals and females are more susceptible to the angiosarcoma-inducing effects of vinyl chloride than young adult animals and males, respectively." 01/01/1981 - "This study suggests that there is no basic difference in ultrastructure between the vinyl chloride-induced hemangiosarcomas and hemangiosarcomas not related to this chemical exposure."
4.	Neoplasms (Cancer) 06/01/2003 - "A meta-analysis was made of studies addressing occupational exposure to vinyl chloride in relation to cancer mortality. " 06/01/2003 - "Meta-analysis of studies of occupational exposure to vinyl chloride in relation to cancer mortality." 06/01/1991 - "A collaborative study of cancer incidence and mortality among vinyl chloride workers." 04/01/2014 - "Hepatobiliary cancer mortality was elevated among workers ever exposed to vinyl chloride (SMR = 3.80, 95% confidence interval 1.89-6.80); directly standardized rates increased with increasing vinyl chloride exposure duration. " 07/01/2010 - "The name and work of Pier Luigi Viola (1917-1985) are unequivocally connected with the history of the discovery of the toxic effects of vinyl chloride, cancer in particular. "
5.	Liver Neoplasms (Liver Cancer) 06/01/2002 - "The SMR for liver cancer decreased with increasing age of first exposure to vinyl chloride monomer. " 01/01/1991 - "Liver cancer rates were greater than expected in white production workers (3 observed/1.6 expected) and included two men assigned more than 40 years ago to vinyl chloride-related departments. " 01/01/1990 - "This same location also exhibited an excess of liver cancer associated with vinyl chloride operations. " 06/01/1989 - "The only significant association between disease risk and cumulative dose was for liver cancer and cumulative dose of vinyl chloride monomer. " 06/01/1989 - "For the subcohort of workers exposed to vinyl chloride monomer, the standardized mortality ratio (SMR) for liver cancer was 333 (90% confidence interval (CI) 202 to 521). "

Related Drugs and Biologics

1.	Styrene (Styrol)
2.	Oils
3.	Dietary Fats (Ghee)
4.	Arsenic
5.	Thorium Dioxide (Thorotrast)
6.	connexin 37
7.	Polyvinyl Chloride (PVC)
8.	Benzene (Benzole)
9.	Asbestos
10.	Mercury

Related Therapies and Procedures

1.	Intensive Care (Surgical Intensive Care)
2.	Radiotherapy
3.	Transplants (Transplant)
4.	Breast Implants (Breast Implant)
5.	Transplantation (Transplant Recipients)