Vasoconstrictor Agents

Drugs used to cause constriction of the blood vessels.

Also Known As:

Vasoconstrictor Drugs; Vasoconstrictors; Agent, Vasoconstrictor; Agent, Vasopressor; Agents, Vasoconstrictor; Agents, Vasopressor; Agonist, Vasoactive; Agonists, Vasoactive; Drug, Vasoconstrictor; Drugs, Vasoconstrictor; Vasoactive Agonist; Vasoactive Agonists; Vasoconstrictor; Vasoconstrictor Agent; Vasoconstrictor Drug; Vasopressor Agent; Vasopressor Agents

Networked: 4570 relevant articles (138 outcomes, 333 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Therapeutic Uses: 47080
    - Cardiovascular Agents: 817
      - Vasoconstrictor Agents: 4570
        Nasal Decongestants: 662
        Calcium Channel Agonists: 37

Experts

1.	Walker, Benjimen R: 16 articles (01/2020 - 01/2002)
2.	Resta, Thomas C: 15 articles (10/2020 - 10/2002)
3.	Lee, Shou-Dong: 15 articles (12/2018 - 02/2004)
4.	Lee, Fa-Yauh: 14 articles (12/2018 - 02/2004)
5.	Jernigan, Nikki L: 13 articles (10/2020 - 05/2013)
6.	Lin, Han-Chieh: 13 articles (02/2018 - 02/2004)
7.	Edvinsson, Lars: 12 articles (01/2022 - 12/2004)
8.	Huang, Hui-Chun: 12 articles (12/2018 - 02/2004)
9.	Jesmin, Subrina: 12 articles (12/2016 - 01/2006)
10.	Barton, Matthias: 12 articles (10/2015 - 11/2002)

Related Diseases

1.	Hepatorenal Syndrome 09/01/2013 - "Various vasoconstrictors have shown promising results in the management of type 1 hepatorenal syndrome (HRS). " 06/01/2012 - "Various vasoconstrictors are useful in the management of hepatorenal syndrome (HRS). " 01/01/2015 - "The efficacy of vasoconstrictors in hepatorenal syndrome (HRS) is variable. " 01/01/2023 - "Previous studies using varying medication doses along with the "old" definition of hepatorenal syndrome (HRS type 1) rather than HRS-AKI means that there is still a need for future multicenter prospective studies further refining the risk-benefit ratio of vasoconstrictors for HRS-AKI patients. " 12/01/2011 - "Therapeutic response to vasoconstrictors in hepatorenal syndrome parallels increase in mean arterial pressure: a pooled analysis of clinical trials."
2.	Hypertension (High Blood Pressure) 10/01/1991 - "These results show the rapid development of functional and structural changes in small resistance arteries in renal hypertensive rats within 4-6 wk of hypertension, with significant reduction in external and lumen diameters, increased media width, and increased media-to-lumen ratio, which enhance vascular reactivity to vasoconstrictors, in particular NE and AVP." 05/23/2023 - "Its potential mechanisms may be associated with the protective effects on renal and cardiac injury caused by hypertension, the decrease of plasma vasoconstrictors, such as ACE, ALD, AngⅡ, and ET-1 levels, the maintenance of NO/ET balance, the increase in plasma NO levels and SOD activity, thereby reducing oxidative stress. " 04/01/2008 - "The purpose of this study was to determine whether skeletal muscle arteriolar vasoconstrictor dysfunction precedes or occurs concurrently with the onset of diabetes and hypertension. " 11/01/1998 - "In this study, we tested the hypothesis that vasoconstrictor action of Ang II is exaggerated in SHR Af-Arts due to an impaired function of the AT2 receptor before development of hypertension. " 02/01/1995 - "The aims of this study were to elucidate the vasoconstrictor mechanism that mediates the changes in celiac and mesenteric vascular resistances during vasoconstriction and hypertension induced by ganglionic blockade and to explore the preferential mechanism that contributes to the elevation of arterial pressure in conscious spontaneously hypertensive rats (SHR). "
3.	Hemorrhage 07/01/2021 - "EVL with short-course vasoconstrictors is highly efficacious for esophageal variceal bleeding. " 11/17/2023 - "Vasoconstrictors reduce portal pressure via splanchnic vasoconstriction and are used in the management of variceal hemorrhage. " 01/01/2023 - "Subgroup analysis indicated patients treated with TXA to have less likelihood of bleeding recurrence, compared to patients treated with vasoconstrictors. " 01/01/2021 - "No severe bleeding and no arrhythmias induced by vasoconstrictor were observed in the two groups. " 01/01/2020 - "Topical application of vasoconstrictors is necessary for endoscopic sinus surgery (ESS) for a bloodless surgical view and reduced intraoperative bleeding. "
4.	Hypotension (Low Blood Pressure) 06/01/2014 - "Administration of an intravenous (IV) vasopressor agent during induction significantly decreased the incidence of hypotension. " 08/01/1993 - "[Changes in the efficacy of vasoconstrictor stimuli in acute and chronic hypotension in the microcirculatory bed of rat skeletal muscle]." 11/01/1994 - "Microneurographic studies have advanced the concept that abrupt paradoxical withdrawal of sympathetic vasoconstrictor drive is an important cause of this episodic hypotension. " 01/01/1985 - "Previous studies have implied that, although both receptors participate in the baroreceptor response to hypotension, only the extrasynaptic alpha 2 receptors are able to maintain the compensatory vasoconstrictor effort for a prolonged period of time. " 11/16/2023 - "Rats subjected to CLP developed hypotension, hyporesponsiveness to vasoconstrictors, an intense inflammatory process, and increased plasma markers of organ dysfunction. "
5.	Pulmonary Hypertension 01/01/2019 - "These data further suggest that loss of ASIC2 enhances the contribution of ASIC1 to overall pulmonary vascular reactivity.NEW & NOTEWORTHY This study demonstrates that loss of ASIC2 leads to increased baseline pulmonary vascular resistance, enhanced responses to a variety of vasoconstrictor stimuli, and greater development of hypoxic pulmonary hypertension. " 10/01/2016 - "Taken together, our results indicate that 2-APB reduces pulmonary hypertension, vasoconstrictor responses and pathological remodeling in pulmonary hypertensive lambs. " 06/01/2012 - "The pathophysiological basis of chronic hypoxic pulmonary hypertension in the mouse: vasoconstrictor and structural mechanisms contribute equally." 01/21/2009 - "The observed effects cannot account for pulmonary hypertension in diabetes, rather the impaired reactivity to vasoconstrictors would counteract the development of pulmonary hypertensive disease." 07/15/2006 - "Consequently, we tested the hypothesis that an increased ET-mediated vasoconstrictor influence contributes to secondary pulmonary hypertension after MI and investigated the involvement of ET(A) and ET(B) receptor subtypes. "

Related Drugs and Biologics

1.	Vasodilator Agents (Vasodilators)
2.	Albumins
3.	Endothelin-1 (Endothelin 1)
4.	Norepinephrine (Noradrenaline)
5.	Terlipressin
6.	Vasoconstrictor Agents
7.	Angiotensin II
8.	Peptides (Polypeptides)
9.	Epinephrine (Adrenaline)
10.	Vasopressins (Vasopressin)

Related Therapies and Procedures

1.	Therapeutics
2.	Liver Transplantation
3.	Drug Therapy (Chemotherapy)
4.	Radiotherapy
5.	Anesthesia