Vanadium

A metallic element with the atomic symbol V, atomic number 23, and atomic weight 50.94. It is used in the manufacture of vanadium steel. Prolonged exposure can lead to chronic intoxication caused by absorption usually via the lungs.

Networked: 393 relevant articles (17 outcomes, 55 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chatterjee, Malay: 13 articles (09/2011 - 11/2003)
2.	Crans, Debbie C: 6 articles (09/2013 - 07/2005)
3.	Chatterjee, M: 6 articles (01/2005 - 08/2000)
4.	Ding, Wenjun: 4 articles (08/2015 - 11/2007)
5.	Willsky, Gail R: 4 articles (12/2009 - 07/2005)
6.	Samanta, Shaonly: 4 articles (10/2008 - 03/2005)
7.	Rana, Ajay: 4 articles (10/2008 - 01/2007)
8.	Ghosh, Balaram: 4 articles (10/2008 - 01/2005)
9.	Sakurai, Hiromu: 4 articles (03/2008 - 01/2002)
10.	Chakraborty, Tridib: 4 articles (01/2007 - 11/2003)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2010 - "Vanadium in several animal cancer models provides protection against all stages of carcinogenesis--initiation, promotion, and progression. " 10/29/2014 - "This is the first study demonstrating that vanadium complexes could induce a p53 dependent apoptotic mechanism in high risk HPV16-positive cervical cancers." 09/01/2011 - "The anti-cancer activity of vanadium and fish oil has been shown in a large number of studies. " 02/29/2008 - "DNA fragmentation study revealed the vanadium-mediated apoptotic induction in colon tumors. " 11/01/2015 - "Vanadium has been emerged as a promising agent owing to its ability to prevent several types of cancer. "
2.	Diabetes Mellitus 03/01/2003 - "Vanadium is currently undergoing clinical trials as an oral drug in patients with noninsulin-dependent diabetes mellitus. " 01/01/2005 - "[Therapeutic potential of vanadium in treating diabetes mellitus]." 01/01/2002 - "A new concept: the use of vanadium complexes in the treatment of diabetes mellitus." 07/01/2000 - "The various nutritional supplements for patients with diabetes mellitus including vanadium-contained used in Russia and abroad are also considered." 12/01/1993 - "A great deal of interest in the element vanadium has been generated recently because of its potential as a therapeutic agent for diabetes mellitus. "
3.	Body Weight (Weight, Body) 06/01/2011 - "The results showed that pups from Group B, exhibited behavioural deficits in most tests, a significant reduction in body weight gain and absolute brain weight; in addition immunohistochemistry showed reactive astrogliosis induced by vanadium exposure. " 06/01/1981 - "It appears that vanadium expresses its toxicity in laying hens by several routes since the protective effects of different dietary changes and additives differentially affected the loss of albumen quality, egg production, body weight, and egg weight." 07/01/2014 - "Neonatal pups exposed to vanadium via lactation for 15 and 22 days all had lower body weights. " 09/01/2011 - "Normal and diabetic rats were given physiological saline, and VACC-treated rats were administered VACC intragastrically at doses of 0.18 mg vanadium/kg body weight once daily. " 01/01/2007 - "Normal and diabetic rats were intragastrically administered VAC at a dose of 3 mg vanadium/kg body weight once daily for 35 consecutive days. "
4.	Insulin Resistance 04/01/2008 - "Till today decrease in insulin resistance by vanadium treatment has been mainly attributed to its potential to inhibit PTP-1B, however the present study opens a new dimension in vanadium treatment for diabetes due to its novel role in adipogenesis." 01/01/2006 - "In the latter case vanadium treatment may not have totally overcome the insulin resistance seen in these animals." 10/01/2008 - "Previous studies showed that bis(alpha-furancarboxylato)oxovanadium(IV) (BFOV), an orally active anti-diabetic organic vanadium complex, could improve insulin resistance in animals with type 2 diabetes. " 10/01/2015 - "Using a combinational approach, we synthesized a vanadium-antioxidant (i.e., l-ascorbic acid) complex and examined its effect on insulin resistance and oxidative stress. " 03/01/2014 - "In addition, vanadium treatment caused a significant suppression of phosphorylation of c-Jun N-terminal protein kinase (JNK), which plays a key role in insulin-resistance in type II diabetes. "
5.	Obesity 02/01/2013 - "This study investigated the anti-obesity effects of Jeju ground water containing the vanadium components S1 (8.0 ± 0.9 μg/l) and S3 (26.0 ± 2.09 μg/l) on the differentiation of 3 T3-L1 preadipocytes and obesity in mice that were fed a high-fat diet (HFD). " 02/01/2013 - "The anti-obesity effect of natural vanadium-containing Jeju ground water." 01/01/2015 - "The primary objective of the current study is to investigate the relationship between adipose tissue chromium and vanadium content and adipose tissue dysfunction in a model of diet-induced obesity. " 09/01/2015 - "If our hypothesis will be confirmed by later studies, adipose tissue chromium, vanadium, and zinc content may be used as a prognostic biomarker of metabolic disturbances in obesity. " 09/01/2015 - "Single indications of high relative adipose tissue trace element content, decreased Cr, V, and Zn content in obese adipose tissue, and tight association between fat tissue chromium, vanadium, and zinc levels and metabolic parameters in obesity may be useful for hypothesis validation. "

Related Drugs and Biologics

1.	Vanadates (Orthovanadate)
2.	Ions
3.	Zinc
4.	Chromium
5.	Micronutrients
6.	Streptozocin (Streptozotocin)
7.	1,2-Dimethylhydrazine (1,2 Dimethylhydrazine)
8.	Glucose (Dextrose)
9.	DNA (Deoxyribonucleic Acid)
10.	acetyl acetonate (acetylacetonate)

Related Therapies and Procedures

1.	Prostheses and Implants (Prosthesis)
2.	Chemoprevention
3.	Therapeutics
4.	Psychosurgery (Lobotomy)
5.	Knee Prosthesis