Uteroglobin

A protein fraction of pregnant uterine fluid which can induce and regulate blastocystic development. Blastokinin is thought to be similar or identical to uteroglobin. Presence in uterine fluid regulated by progesterone.

Also Known As:

Networked: 89 relevant articles (2 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Kimura, Shioko: 6 articles (01/2011 - 03/2002)
2.	Zhang, Zhongjian: 4 articles (03/2008 - 03/2005)
3.	Mukherjee, Anil B: 4 articles (03/2008 - 03/2005)
4.	Shim, Young-Soo: 3 articles (09/2010 - 04/2003)
5.	Han, Sung Koo: 3 articles (09/2010 - 04/2003)
6.	Lee, Choon-Taek: 3 articles (09/2010 - 04/2003)
7.	Yoo, Chul-Gyu: 3 articles (09/2010 - 04/2003)
8.	Kim, Young Whan: 3 articles (09/2010 - 04/2003)
9.	Choi, Moonsuk: 3 articles (06/2006 - 03/2005)
10.	Tassi, Renata A: 2 articles (01/2013 - 06/2007)

Related Diseases

1.	Hyperplasia 12/01/2001 - "Uteroglobin promoter-targeted c-MYC expression in transgenic mice cause hyperplasia of Clara cells and malignant transformation of T-lymphoblasts and tubular epithelial cells." 08/01/2001 - "Adenoviral mediated uteroglobin gene transfer to the adventitia reduces arterial intimal hyperplasia." 12/01/2000 - "We hypothesize that induction of uteroglobin expression in the artery wall by local adenoviral gene transfer will decrease neointimal hyperplasia in the rat carotid artery after balloon injury. " 12/01/2000 - "Adenoviral-mediated uteroglobin gene transfer inhibits neointimal hyperplasia after balloon injury in the rat carotid artery." 08/01/2001 - "The aim of this study was to investigate the feasibility of gene transfer of uteroglobin, a potent anti-inflammatory and immunomodulatory agent, via adenoviral mediated gene transfer to the adventitia in the mouse carotid ligation injury model and also to investigate the efficacy of uteroglobin in reducing neointimal hyperplasia. "
2.	Neoplasms (Cancer) 03/15/2006 - "Mandal et al. (1999) Loss of transformed phenotype in cancer cells by overexpression of the uteroglobin gene. " 03/15/2006 - "Interaction of uteroglobin with lipocalin-1 receptor suppresses cancer cell motility and invasion." 07/01/2003 - "Uteroglobin was confirmed to be abundantly expressed in normal lung and the different lung tumors showed down-regulated uteroglobin expression. " 04/01/2003 - "Recent experimental evidence indicates that uteroglobin has an inhibitory effect on the proliferation and invasion of cancer cells. " 09/01/2002 - "Uteroglobin -/- knockout mice appear to be extremely cancer prone. "
3.	Prostatic Neoplasms (Prostate Cancer) 09/01/2002 - "In this paper, we will briefly discuss the therapeutic potential of uteroglobin-based strategies for managing prostate cancer." 09/01/2002 - "Uteroglobin: a potential novel tumor suppressor and molecular therapeutic for prostate cancer."
4.	IGA Glomerulonephritis (IGA Nephropathy) 07/01/2006 - "Six studies involving uteroglobin G38A genotyping of 930 patients with IgA nephropathy and 768 healthy controls were included. " 07/01/2006 - "However, several association studies of uteroglobin G38A polymorphism and IgA nephropathy showed controversial findings. " 04/01/2015 - "Association of uteroglobin G38A gene polymorphism and IgA nephropathy (IgAN) risk is still not clear. " 04/01/2015 - "Association of uteroglobin G38A gene polymorphism with IgA nephropathy risk: an updated meta-analysis." 07/01/2006 - "We suggest that uteroglobin G38A polymorphism is not related to the development and progression of IgA nephropathy."
5.	Asthma (Bronchial Asthma) 11/01/2007 - "The secretory protein, uteroglobin-related protein 1 (UGRP1), is expressed mainly in the lung and trachea and recently has been implicated in asthma. " 11/01/2007 - "Uteroglobin-related protein 1 gene -112G/a polymorphism and atopic asthma in Sicilian children." 03/18/2005 - "Uteroglobin suppresses SCCA gene expression associated with allergic asthma." 01/01/2005 - "The secretory protein, uteroglobin-related protein 1 (UGRP1), is mainly expressed in the lung and trachea and has recently been implicated in asthma. " 01/01/2005 - "Uteroglobin-related protein 1(UGRP1) gene polymorphisms and atopic asthma in the Indian population."

Related Drugs and Biologics

1.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
2.	Progesterone
3.	Progesterone Receptors (Progesterone Receptor)
4.	Clara cell secretory protein
5.	Chymases (Chymase)
6.	Interleukin-10 (Interleukin 10)
7.	Transforming Growth Factor beta (TGF-beta)
8.	Interleukin-4 (Interleukin 4)
9.	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
10.	Proteins (Proteins, Gene)

Related Therapies and Procedures

1.	Ligation