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Urologic Diseases (Urinary Tract Disease)

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Pathological processes of the URINARY TRACT in both males and females.

Also Known As:

Urinary Tract Disease; Urological Diseases; Disease, Urinary Tract; Disease, Urologic; Disease, Urological; Diseases, Urinary Tract; Diseases, Urologic; Diseases, Urological; Urologic Disease; Urological Disease; Urinary Tract Diseases

Networked: 480 relevant articles (23 outcomes, 32 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Urinary Bladder Neoplasms (Bladder Cancer)
2.	Hematuria
3.	Chronic Kidney Failure (Chronic Renal Failure)
4.	Urinary Tract Infections (Urinary Tract Infection)
5.	Pathologic Constriction (Stenosis)

Experts

1.	Moyad, Mark A: 6 articles (04/2007 - 04/2006)
2.	Merrick, Gregory S: 5 articles (04/2007 - 04/2006)
3.	Kuo, Hann-Chorng: 3 articles (03/2012 - 09/2010)
4.	Tyagi, Pradeep: 3 articles (04/2011 - 02/2010)
5.	Arakawa, Soichi: 3 articles (04/2011 - 03/2002)
6.	Chew, Ben H: 2 articles (01/2015 - 05/2006)
7.	Studer, Urs E: 2 articles (01/2015 - 07/2004)
8.	Abol-Enein, Hassan: 2 articles (01/2015 - 06/2006)
9.	Holdenrieder, Stefan: 2 articles (01/2015 - 01/2003)
10.	Wang, Wei: 2 articles (01/2014 - 01/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Urologic Diseases:

1.	Amitriptyline (Elavil)FDA LinkGeneric 06/01/2003 - "The short-term clinical efficacy of amitriptyline in the management of idiopathic feline lower urinary tract disease: a controlled clinical study." 03/15/2003 - "Randomized controlled trial of the efficacy of short-term amitriptyline administration for treatment of acute, nonobstructive, idiopathic lower urinary tract disease in cats." 06/01/2003 - "In a controlled study, the effects of amitriptyline compared with that of a placebo in cats suffering from idiopathic Feline Lower Urinary Tract Disease (FLUTD) have been investigated. " 03/15/2003 - "To determine whether short-term amitriptyline administration would be efficacious in the treatment of acute, nonobstructive, idiopathic lower urinary tract disease in cats. " 03/15/2003 - "Results suggest that short-term amitriptyline treatment has no benefit in terms of resolution of pollakiuria and hematuria in cats with idiopathic lower urinary tract disease and may be associated with an increased risk of recurrence."
2.	CreatinineIBA 01/01/1995 - "Urine samples were obtained from 143 adult patients comprising 60 control subjects with no evidence of urinary tract disease and 83 patients with serum creatinine > 1.5 mg/dL. " 01/01/1989 - "It is concluded that "imaging" of the urinary tract is only indicated in cases of haematuria, elevated creatinine, history of renal calculous disease and other clinical suspicion of upper urinary tract disease. " 06/01/1988 - "[Enzymuria and creatinine clearance in the clinico-laboratory evaluation of kidney damage in urological disease]." 02/01/2005 - "The patients with bladder cancer had significantly greater levels of BTF and the BTF/CREA ratio than did the healthy subjects (P <0.001) and, in the case of BTF without correcting for creatinine, than did the patients with benign urologic disease (P <0.05). " 09/01/2007 - "Urinary CA19-9 and DU-PAN-2 levels were measured as units per mg creatinine (U/mg Cr) in 121 patients with bladder cancer and in 31 patients with other urologic diseases. "
3.	Anti-Bacterial Agents (Antibiotics)IBA 04/01/2011 - "We classified all cases into 49 cases of complicated AP and 24 cases of uncomplicated AP according to the presence of underlying urinary tract diseases, and examined the characteristics of the patients and the efficacy of the antibiotics used in this study. " 08/01/2004 - "Many children with urological disease require long-term treatment with antibiotics. " 05/01/1997 - "[The etiological structure of the causative agents of inflammatory nonspecific urological diseases and the dynamics of their resistance to the widely used antibiotics]." 07/01/1971 - "[Combined effect of some antibacterial agents on the development of drug resistance of Escherichia coli strains isolated in inflammatory urinary tract diseases]." 01/01/1954 - "[Application of antibiotics in urological diseases]."
4.	AntigensIBA 09/30/1977 - "[Indirect hemagglutination against polyvalent colibacillary antigen in urinary tract diseases]." 11/19/1971 - "coli antigen in urinary tract diseases]." 08/01/2001 - "Bladder cancer antigen had the least false-positive results in patients with a history of bladder cancer and negative cystoscopy, and those with urological disease other than bladder cancer. " 03/01/2002 - "Although this bladder tumor antigen test was sensitive for differentiating dogs with malignancies of the lower urinary tract from dogs without urinary tract disease, it was not specific for differentiating dogs with neoplasia from dogs with other lower urinary tract abnormalities. " 04/01/1999 - "Urinary bladder cancer antigen was measured in urine from 86 patients with active transitional cell carcinoma of the bladder (group 1), 76 patients free of transitional cell carcinoma as confirmed by cystoscopy at followup (group 2), 25 patients with other benign urological diseases (group 3), 25 patients with other malignant pathological conditions (group 4) and 30 healthy subjects free of urological diseases (group 5). "
5.	Gentamicins (Gentamicin)FDA LinkGeneric 03/01/1976 - "1. Gentamicin was effective in 20 patients out of 25 with urological diseases. " 09/01/1978 - "[Use of gentamicin sulfate in treating urologic diseases]." 03/01/1976 - "[Clinical experiment of gentamicin in patients with urological diseases (author's transl)]." 04/01/1984 - "58.0 and 90.3 per cent of the strains isolated from patients with intestinal infections, 66.6 and 100 per cent of the strains isolated from patients with otitis, 33.3 and 66.6 per cent of the strains isolated from patients with bronchopulmonary affections and 100 and 100 per cent of the strains isolated from patients with urological diseases were resistant to gentamicin and carbenicillin, respectively. " 02/01/1978 - "Children suffering from urological diseases showed a slower excretion of gentamicin, even when creatinine and urea concentrations in serum were not elevated. "
6.	nuclear matrix protein 22IBA 01/01/2006 - "BTA TRAK, BTA stat, NMP22, and NMP22 BladderChek assays are limited by false-positive results in patients with benign urological diseases such as hematuria, urocystitis, renal calculi or urinary tract infections. " 09/14/2005 - "We detect VUC, BTAstat, NMP22, HA, Survivin, CD44v6, VEGF in the urine of 10 normal case (healthy volunteers), 11 benign urological diseases patients and 52 bladder cancer patients. " 01/01/2003 - "Following the recommendations of the European Group on Tumor Markers we used 95% specificity for benign urological diseases and urinary tract infections, which resulted in a sensitivity of 17% for active bladder cancer for the BTA-TRAK assay and 31% for NMP22. "
7.	Prazosin (Minipress)FDA LinkGeneric 07/01/1993 - "We conclude that Prazosin is an alpha-blocker useful in early prostate disorders and when no obstructive urological disease is present." 07/01/1995 - "These results indicate that dantrolene and prazosin may be effective in relaxing intraurethral skeletal and smooth musculature in male cats clinically afflicted with obstructive lower urinary tract disease. " 07/01/1995 - "The effects of the skeletal muscle-relaxing drug dantrolene sodium alone, and in combination with the alpha 1-adrenergic antagonist prazosin, on the urethral pressure profile were investigated in male cats with obstructive lower urinary tract disease. "
8.	Renal cell carcinoma 1IBA 06/01/2006 - "Positive results were obtained in 2 patients with renal cell carcinoma, 1 with hematuria and 1 with a contracted bladder but in none with other urological diseases. " 11/15/1981 - "Of 2 horses with renal cell carcinoma, 1 had massive ascites but no other signs of urinary tract disease; the other had hematuria. "
9.	Dantrolene (Dantrium)FDA LinkGeneric 07/01/1995 - "These results indicate that dantrolene and prazosin may be effective in relaxing intraurethral skeletal and smooth musculature in male cats clinically afflicted with obstructive lower urinary tract disease. " 07/01/1995 - "The effects of the skeletal muscle-relaxing drug dantrolene sodium alone, and in combination with the alpha 1-adrenergic antagonist prazosin, on the urethral pressure profile were investigated in male cats with obstructive lower urinary tract disease. "
10.	Cinoxacin (Cinobac)FDA Link 08/01/1980 - "It is concluded that cinoxacin will be useful in the treatment of urinary tract disease because of the high urinary antibacterial activity produced. "

Therapies and Procedures

1.	Nephrectomy 01/01/1999 - "The last decade marks the introduction of laparoscopic nephrectomy (RV Clayman et al, 1991, AD Joce et al, 1992, JJ Rassweller et al, 1993, Sy Nakada et al, 1996, CC Abbou et al, 1998) which is a safe procedure even in patients with malignant renal pathology and adequately selected cases presenting various urological diseases." 12/01/1986 - "Twenty-six normotensive patients, who underwent unilateral nephrectomy for nontumoral urological diseases, were reevaluated. " 06/01/2012 - "Laparoscopic procedures for urologic diseases in children, such as pyeloplasty, orchiopexy, nephrectomy, and bladder augmentation, have proven to be safe and effective with outcomes comparable to those of open techniques. " 01/01/2009 - "Laparoscopic procedures for urological diseases in children, such as nephrectomy, pyeloplasty and orchiopexy, have proven to be safe and effective with outcome comparable to the open procedure. " 01/19/2005 - "Forty-five patients with urologic diseases underwent hand-assisted laparoscopic renal surgery: radical nephrectomy was performed on 23 cases, simple nephrectomy on 9 cases, nephroureterectomy on 8 cases, excision of cysts of kidney on 3 cases, partial nephrectomy on 1 case, and upper pole heminephrectomy in duplex kidney on 1 case. "
2.	Transplantation (Transplant Recipients) 02/27/1994 - "Of these recipients 44% had complex congenital urologic disease and required urologic surgery prior to or at the time of transplantation. " 01/01/2008 - "However, our data suggested that renal transplantation is a safe and effective treatment modality, if the underlying urologic diseases properly managed during the transplantation course. " 05/01/2013 - "Kidneys could be restored from urologic disease for transplantation after excision of a small tumor with satisfactory outcomes at an average follow-up of 26 months. " 02/01/2005 - "Between January 1986 and January 2001, 281 patients underwent renal transplantation, and 23 urologic surgical procedures were performed on 21 transplant recipients before or after renal transplantation because of de novo urologic diseases. " 02/01/2014 - "Significant improvement in the cystometry and PFS parameters was observed in patients with end-stage renal disease, without urologic disease, 6 months after transplantation, and was associated with recovery of the glomerular filtration rate and urine output by the renal graft."
3.	Orchiopexy 06/01/2012 - "Laparoscopic procedures for urologic diseases in children, such as pyeloplasty, orchiopexy, nephrectomy, and bladder augmentation, have proven to be safe and effective with outcomes comparable to those of open techniques. " 01/01/2009 - "Laparoscopic procedures for urological diseases in children, such as nephrectomy, pyeloplasty and orchiopexy, have proven to be safe and effective with outcome comparable to the open procedure. "
4.	Kidney Transplantation 01/01/2006 - "The study group (30 patients) consisted of 9 children (30%) undergoing renal transplantation with an underlying urological disease and 21 (70%) with an underlying nephrological disease. " 04/01/2008 - "Long-term renal transplantation survivors show high prevalences of treatable urologic diseases. " 01/01/2008 - "However, our data suggested that renal transplantation is a safe and effective treatment modality, if the underlying urologic diseases properly managed during the transplantation course. " 11/01/1997 - "Innovative urologic reconstructive surgery using enteric segments for both continent and incontinent urinary diversions has permitted this therapeutic modality to be offered to the recipient with lower urinary tract disease not previously amenable to renal transplantation. " 02/01/2005 - "Between January 1986 and January 2001, 281 patients underwent renal transplantation, and 23 urologic surgical procedures were performed on 21 transplant recipients before or after renal transplantation because of de novo urologic diseases. "
5.	Transplants (Transplant) 03/01/2013 - "Subjects included children receiving liver, kidney or hematopoietic stem cell transplants and patients with oncologic or urologic disease. " 06/01/2011 - "Pretransplant urological evaluation aims to diagnose, treat, and optimize any preexisting urological disease that can jeopardize transplant evolution. " 02/01/2011 - "Tissue-engineered grafts for the urinary tract are being investigated for the potential treatment of several urologic diseases. " 08/01/2009 - "Such subclinical urological diseases in the grafts might affect the prognosis of renal function. " 01/01/2005 - "Three graft losses were related to urological disease. "