Ureterocele

A cystic dilatation of the end of a URETER as it enters into the URINARY BLADDER. It is characterized by the ballooning of the ureteral orifice into the lumen of the bladder and may obstruct urine flow.

Also Known As:

Networked: 354 relevant articles (32 outcomes, 14 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Ureterocele
2.	Vesico-Ureteral Reflux (Vesicoureteral Reflux)
3.	Hydronephrosis
4.	Calculi (Calculus)
5.	Urinary Tract Infections (Urinary Tract Infection)

Experts

1.	Chertin, Boris: 5 articles (05/2018 - 08/2002)
2.	Kajbafzadeh, Abdol-Mohammad: 4 articles (04/2022 - 01/2018)
3.	Castagnetti, Marco: 4 articles (10/2021 - 03/2012)
4.	Pohl, Hans G: 4 articles (02/2020 - 10/2005)
5.	Puri, Prem: 4 articles (02/2012 - 08/2002)
6.	Nabavizadeh, Behnam: 3 articles (09/2020 - 01/2018)
7.	Mizuno, Kentaro: 3 articles (11/2018 - 11/2006)
8.	Kropp, Bradley P: 3 articles (10/2017 - 01/2005)
9.	Elder, Jack S: 3 articles (12/2015 - 04/2004)
10.	El-Ghoneimi, Alaa: 3 articles (05/2015 - 06/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ureterocele:

1.	PlasticsIBA 05/01/2005 - "The best results were achieved in plastic modified operations and endoscopic correction of ureterocele. " 05/01/2005 - "[Intravesical plastic reconstruction of the ureter in orthotopic ureterocele]."
2.	Contrast MediaIBA 01/01/1997 - "The ectopic ureterocele produces a filling defect of variable size in the bladder; it can be identified with contrast material studies or ultrasound. " 01/01/2018 - "Uroscanner showed right giant ureteropyelocaliceal dilation (pyelon measuring 15.2cm) completely eroding the renal parenchyma with absence of contrast agent excretion, upstream of ureterocele complicated by a stone measuring 2cm. " 07/01/1998 - "Ultrasonography is a practical method for diagnosis of ectopic ureter, ureterocele, and certain causes of ureteral obstruction that compares favorably with contrast radiography because it is quicker, does not involve use of contrast media or ionizing radiation, and usually requires no sedation or anesthesia. "
3.	yttrium-aluminum-garnetIBA 07/01/2006 - "The use of the holmium:yttrium-aluminum-garnet (YAG) laser to incise a ureterocele in children has been reported. " 01/01/2020 - "Few case series report the use of holmium: yttrium-aluminum-garnet (Ho:YAG) laser to decompress ureterocele (UC) in pediatric population, and only two studies compared its outcomes with electrosurgery. " 07/01/2006 - "Holmium: yttrium-aluminum-garnet laser puncture of ureteroceles in neonatal period." 01/01/2020 - "Holmium: Yttrium-aluminum-garnet laser for endoscopic decompression of ureterocele in the first months of life: A comparison with electrosurgery." 04/01/2003 - "In a case of severe bilateral hydronephrosis in a female fetus associated with ureterocele at 28 weeks, under local anesthetic, ultrasound-guided neodymium:yttrium-aluminum-garnet laser was used to perforate the ureterocele and successfully overcome the obstruction. "
4.	HolmiumIBA 07/01/2006 - "The use of the holmium:yttrium-aluminum-garnet (YAG) laser to incise a ureterocele in children has been reported. " 01/01/2020 - "Few case series report the use of holmium: yttrium-aluminum-garnet (Ho:YAG) laser to decompress ureterocele (UC) in pediatric population, and only two studies compared its outcomes with electrosurgery. " 07/01/2006 - "Holmium: yttrium-aluminum-garnet laser puncture of ureteroceles in neonatal period." 01/01/2020 - "Holmium: Yttrium-aluminum-garnet laser for endoscopic decompression of ureterocele in the first months of life: A comparison with electrosurgery."
5.	Anti-Bacterial Agents (Antibiotics)IBA 04/01/2018 - "Children with prenatally detected ureterocele or duplex collecting system associated with nonrefluxing megaureter are at high risk of UTI despite prophylactic antibiotics. " 06/01/2008 - "Definitive treatment of ectopic ureterocele (EU) implies that no further surgery or prophylactic antibiotic is needed. " 02/01/2020 - "The majority of respondents never or rarely prescribe antibiotics for horseshoe or solitary kidney (88% and 86%, respectively), but frequently prescribed antibiotic for ureterocele. " 01/01/1997 - "Renal and bladder ultrasound and radiographic micturating cystourethragraphy under antibiotic cover will both detect vesicoureteric reflux and assess any bladder outlet obstruction due to the ureterocele. " 05/01/1984 - "Management of an infant or child with a ureterocele should begin with appropriate antibiotic treatment if infection is present, followed by excision or drainage of the involved renal segment(s). "
6.	Succimer (Dimercaptosuccinic Acid)FDA Link 09/01/2016 - "Can renal ultrasonography and DMSA scintigraphy be used for the prediction of irreversible histological lesions of the upper pole in duplex system with ureteroceles or ectopic ureters?" 07/01/1991 - "In the remaining two cases the suction of the ureterocele was done, as well as the ureteropyelostomy, since it was necessary to use the upper hemi-kidney in the renal TC99m dimercaptosuccinic acid scan-DMSA. " 02/01/2012 - "Other anomalies were: bladder diverticulum in 29, solitary kidney in 12, ureterocele in 13, hypospadiasis in 11, pelviureteric junction obstruction in 9, malrotated kidney in 3, horseshoe kidney in 2, crossed fused ectopia in 1 and renal cyst in 1. DMSA scan revealed renal scarring in 105 (47.7%) of the 220 children who had a DMSA scan. " 03/01/2002 - "Further evaluation including voiding cystourethrography (VCUG), Tc-99m dimercaptosuccinic acid (DMSA) scan, intravenous urography (IVU) showed a ureterocele and hydroureteronephrosis in the upper moiety of a left duplicated kidney. " 01/01/2023 - "Clinical data including age at diagnosis, body weight, history of UTI, ureteroceles, ectopic ureteral opening, VUR grade, serum creatinine level, cystatin C level, renal scarring, split renal function in dimercaptosuccinic acid scans, and effective renal plasma flow (ERPF) were analyzed. "
7.	Polytetrafluoroethylene (Teflon)FDA Link 01/01/1990 - "On one hand, by incising or resecting the ureterocele and, on the other hand, by suppressing the reflux thus created with a Teflon injection under the gaping ureterocele. " 01/01/1990 - "Endoscopic treatment of ureterocele and antireflux injection with Teflon paste." 01/01/1990 - "On the basis of 5 cases, the author show the possibilities of treating certain ureteroceles via an endoscopic approach only with incision of the ureterocele and elimination of the reflux thus created by an injection of teflon paste under the gaping ureterocele. " 10/01/1988 - "The ureterocele caused frequent urinary retention and it was treated successfully by a staged endoscopic procedure, consisting of complete transurethral resection of the ureterocele followed by perimeatal polytetrafluoroethylene (Teflon) paste injections to prevent subsequent vesicoureteral reflux. " 01/01/1990 - "The authors present their experience (24 children) with the endoscopic subureteral injection of Teflon paste in the correction of secondary vesicoureteral reflux: reimplantation failure; ureterocele; obstructive bladder; exstrophy; postchemocystitis, and Hutch's diverticulum. "
8.	Ointments (Pastes)IBA 01/01/1990 - "Endoscopic treatment of ureterocele and antireflux injection with Teflon paste." 01/01/1990 - "On the basis of 5 cases, the author show the possibilities of treating certain ureteroceles via an endoscopic approach only with incision of the ureterocele and elimination of the reflux thus created by an injection of teflon paste under the gaping ureterocele. " 10/01/1988 - "The ureterocele caused frequent urinary retention and it was treated successfully by a staged endoscopic procedure, consisting of complete transurethral resection of the ureterocele followed by perimeatal polytetrafluoroethylene (Teflon) paste injections to prevent subsequent vesicoureteral reflux. " 01/01/1990 - "The authors present their experience (24 children) with the endoscopic subureteral injection of Teflon paste in the correction of secondary vesicoureteral reflux: reimplantation failure; ureterocele; obstructive bladder; exstrophy; postchemocystitis, and Hutch's diverticulum. "
9.	Calcium Carbonate (Limestone)FDA Link 12/01/2003 - "Endoscopic management of milk of calcium-filled ureterocele stump." 08/01/1982 - "Milk of calcium ureterocele." 01/01/1981 - "Obstructed ureterocele with milk of calcium." 01/01/1981 - "Milk of calcium and ureterocele." 12/01/2003 - "At cystoscopy, the ureterocele was incised with a holmium:YAG laser, releasing a large quantity of white milky fluid (milk of calcium). "
10.	SolutionsIBA 02/01/2015 - "Examining trends in the treatment of ureterocele yields no definitive solution." 01/01/1999 - "When the superior renal pelvis is functional, ureteropelvic anastomosis is a good solution, especially when the superior ureter is very large and poorly functional, but endoscopic opening of the ureterocele can also be proposed, which may need to be followed be intravesical reconstruction." 05/01/2018 - "Does endoscopic puncture of ureterocele provide not only an initial solution, but also a definitive treatment in all children? "

Therapies and Procedures

1.	Punctures 02/01/2012 - "Transurethral puncture or endoscopic unroofing is the best treatment currently used for both orthotopic and ectopic ureteroceles. " 01/01/2011 - "Our data have shown that primary endoscopic puncture of a ureterocele is a simple, long-term, effective, and safe procedure, avoiding complete reconstruction in most patients." 01/01/2003 - "Our data suggest that primary endoscopic puncture of ureteroceles is a simple, long-term, effective, and safe procedure avoiding complete reconstruction in the majority of the patients." 01/01/2023 - "Transurethral endoscopic incision or puncture is effective for decompressing the obstruction of the upper urinary tract in acute urosepsis in ectopic duplex system ureterocele. " 01/01/2022 - "Our data report primary endoscopic puncture of ureterocele as a simple, effective, and safe procedure also in long-term follow up. "
2.	Decompression 03/01/1998 - "Endoscopic incision permitted decompression of the majority of ureteroceles and improvement in renal function in most cases. " 05/01/2015 - "All patients with ureterocele demonstrated partial or complete decompression of the ureterocele and improvement in hydroureteronephrosis at 3 months. " 01/01/2019 - "Conclusions: Early endoscopic decompression should be considered first line treatment of obstructing ureterocele in infants and children. " 04/01/2017 - "At this stage of our study with median follow-up of 5years (6months-10years), we suggest that primary endoscopic deroofing with DJ stenting for obstructing ureterocele is the best initial approach for adequate decompression and reducing the rate of secondary surgery." 01/01/2023 - "Given comparable success and durability over time to other TUI ureterocele techniques, and with the advantage of operator ease using consistent anatomic landmarks, RIO is a worthy option for endoscopic ureterocele decompression."
3.	Laser Therapy (Surgery, Laser) 03/01/2019 - "Cystoscopic-guided laser ablation was effective for the treatment of ureteroceles(s) in 11 of 13 dogs." 08/01/2021 - "Cystoscopic- guided laser ablation of ureteroceles was effective and safe in these 2 dogs. " 06/01/2015 - "This study aimed to retrospectively evaluate the safety and efficacy of transurethral photoselective Greenlight(™) laser vaporization in adult patients with orthotopic ureterocele. " 12/01/2022 - "For these two cases, fetal surgery was performed using laser ablation of the ureterocele through an ultrasound-guided needle. " 12/01/2022 - "Fetal surgery for obstructive ureterocele using an ultrasound-guided needle laser ablation technique: a case series."
4.	Nephrectomy 06/01/2002 - "Prenatally diagnosed intravesical ureteroceles may be cured by endoscopic incision alone but for extravesical ureteroceles partial nephrectomy appears to be more definitive." 06/01/2002 - "All 10 prenatally diagnosed extravesical ureteroceles treated with partial nephrectomy were cured. " 11/01/2001 - "We consider the heminephrectomy the treatment of choice in pyeloureteral duplication associated with ureterocele and ectopic ureter when gammagraphy studies show hypofunctioning upperpole." 06/01/2022 - "Ureterocele excision was performed in ten patients, laparoscopic heminephrectomy was performed in six patients, and ureteroneocystostomy was performed in one patient. " 04/01/2022 - "Fourteen units of duplex systems underwent upper pole partial nephrectomy in conjunction with augmentation revascularized pyeloureterocystoplaty and ureterocele unroofing. "
5.	Replantation 03/01/2021 - "Pneumovesicoscopic access for ureteral reimplantation in patients with VUR, obstructive megaureter, bladder diverticulum and ureterocele has proven its efficiency and reliability with a minimal complication rate (5.7%). " 03/01/2021 - "Reimplantation for grade 3-5 VUR was performed in 22 patients (26 ureters), in combination with excision of the bladder diverticulum was done in 3 patients, while 3 children were undergone to simultaneous excision of the ureterocele. " 11/01/2018 - "In this review, we summarize the recent viewpoints on RALS, such as pyeloplasty, ureteral reimplantation, bladder neck reconstruction, bladder neck sling, appendicovesicostomy, bladder diverticulectomy, and treatments for ureterocele or ectopic ureters, and we also critically summarize the current status of the literature. " 02/23/2018 - "Ureteral reimplantation and bladder neck reconstruction appears to be unnecessary in a significant portion of the DSU population, but ureterocele treatment needs to be individualized. " 01/01/2018 - "Pyeloplasty (48.8%), ureteral reimplantation/ureterocele reconstruction (41.5%) and other (9.8%) surgical techniques were included. "