Turpentine

The concrete oleoresin obtained from Pinus palustris Mill. (Pinaceae) and other species of Pinus. It contains a volatile oil, to which its properties are due, and to which form it is generally used. (Dorland, 28th ed) Turpentine is used as a solvent and an experimental irritant in biomedical research. Turpentine toxicity is of medical interest.

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Networked: 713 relevant articles (9 outcomes, 70 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Ramadori, Giuliano: 10 articles (01/2013 - 03/2005)
2.	Malik, Ihtzaz Ahmed: 5 articles (06/2013 - 11/2010)
3.	Luheshi, Giamal N: 5 articles (01/2013 - 08/2007)
4.	Naz, Naila: 4 articles (06/2013 - 11/2010)
5.	Moriconi, Federico: 4 articles (06/2013 - 11/2010)
6.	Ishiwata, Kiichi: 4 articles (02/2013 - 01/2006)
7.	Aguilar-Valles, Argel: 4 articles (01/2013 - 08/2007)
8.	Sheikh, Nadeem: 4 articles (01/2013 - 07/2007)
9.	van Waarde, Aren: 4 articles (03/2012 - 04/2004)
10.	Pârvu, Alina Elena: 4 articles (10/2007 - 06/2002)

Related Diseases

1.	Inflammation 01/01/2012 - "A comparative uptake study of multiplexed PET tracers in mice with turpentine-induced inflammation." 01/01/2012 - "The aim of this study was to investigate the synthesis of α(2)-macroglobulin (α2M) in hepatopathic rats injected with turpentine oil to induce acute inflammation. " 01/01/2008 - "Finally, ex vivo biodistribution and blocking studies were carried in rats with a sterile inflammation, induced by intramuscular turpentine injection. " 09/01/2000 - "131I-ORN was also administered intraperitoneally to rats with turpentine-induced inflammation, for quantitative biodistribution studies. " 10/01/1999 - "Trophic response of the intestinal mucosa to inflammation in rats injected with turpentine: a study using pair-fed controls."
2.	Acute-Phase Reaction 07/01/2007 - "In the present study, turpentine oil was injected in the hind limb muscle of the rat to stimulate an acute-phase response (APR). " 01/15/2006 - "To study the way in which the acute-phase response induced by sterile tissue injury influences pulmonary host defense, mice were injected subcutaneously with turpentine or saline in both hind limbs either 2 or 5 days before intranasal inoculation with A. " 04/01/2004 - "These in vitro results were confirmed by in vivo studies in IL-6(-/-) mice injected with turpentine, an experimental model of acute-phase response. " 01/01/1996 - "In this study, an acute phase response was induced by subcutaneous turpentine injection in rats. " 04/01/2011 - "Intra-muscular injection of turpentine oil was used to induce acute phase response (APR) in Atlantic cod (Gadus morhua L.). "
3.	Abscess 11/01/1996 - "Scintigraphic studies in experimental mice have demonstrated high levels of accumulation of 99Tcm-citrate in turpentine-induced abscess (target-to-non-target ratio 4.2:1) and EAT implanted tumour in mice (T/NT 5:1) 1 h after its administration. " 01/01/2013 - "Rats were administered turpentine-oil (TO) intramuscularly to induce a sterile abscess (acute-phase-model) and sacrificed at different time points. " 05/01/2011 - "Rats were administered turpentine oil (TO) intramuscularly to induce a sterile abscess and killed at various time points. " 01/01/2010 - "(99m)Tc-HYNIC-AnxV associated with bacterial abscesses was 1.25+/-0.09 and 3.75+/-0.83 percent injected dose per gram (%ID/g) at 4 and 24 h compared to turpentine abscesses which was 1.02+/-0.16 and 0.72+/-0.17 %ID/g at 4 (P<or=.05) and 24 h (P<or=.01). " 02/01/2006 - "Effects of chronic exercise conditioning on thermal responses to lipopolysaccharide and turpentine abscess in female rats."
4.	Arthritis (Polyarthritis) 07/01/1971 - "Experimental turpentine arthritis: measurement of treated and untreated inflammatory response by the accumulation of 125I-albumin." 04/01/1992 - "Acute chemical arthritis was induced in right radiocarpal joints of eight cow calves by intraarticular injections of turpentine oil. " 01/01/1973 - "[Use of turpentine baths in treating rheumatoid polyarthritis]." 06/01/1987 - "CRP serum level of rats injured by turpentine injection or two different arthritis models was determined to test the potency of this protein as an marker of inflammation. " 06/01/2015 - "The different doses of the UFD showed the protective effect against turpentine oil, formaldehyde induced acute arthritis and CFA induced chronic arthritis at dose dependent manner. "
5.	Edema 01/01/2004 - "It also showed activity against formalin-induced rat paw edema, as well as, turpentine-induced exudative changes and cotton pellet-induced granular tissue formation after oral treatment for 7 days in albino rats. " 05/01/2007 - "The oil has been found to be effective against formaldehyde or adjuvant induced arthritis and turpentine oil induced joint edema in animals. " 08/01/2013 - "A new series of 4,5-dihydro-2H-indazoles was synthesized and evaluated for anti-inflammatory activity using formalin-induced paw edema and turpentine oil-induced granuloma pouch bioassays. " 01/01/2013 - "After 7 days of treatment, both LPGE and LPEE showed 26.3% (P < 0.01) and 32.5% (P < 0.05) inhibition, respectively, against formalin-induced paw edema, and reduced weight of turpentine-induced granuloma pouch by 42.8% and 36.1% (P < 0.001), and volume of exudates by 31.2% and 36.2% (P < 0.001), respectively. " 03/01/2010 - "The active compounds were further studied in vivo by using the formalin-induced paw edema and the turpentine oil-induced granuloma pouch bioassays. "

Related Drugs and Biologics

1.	Formaldehyde (Formol)
2.	Interleukin-1 (Interleukin 1)
3.	Acute-Phase Proteins (Acute-Phase Protein)
4.	alpha-Macroglobulins (alpha 2 Macroglobulin)
5.	Interleukin 1 Receptor Antagonist Protein (Anakinra)
6.	Type I Tumor Necrosis Factor Receptors
7.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
8.	Dexamethasone (Maxidex)
9.	Antipyrine (Phenazone)
10.	Edetic Acid (EDTA)

Related Therapies and Procedures

1.	Baths
2.	Intramuscular Injections
3.	Heterologous Transplantation (Xenotransplantation)
4.	Catheters
5.	Homologous Transplantation (Allograft)