Tuberculous Peritonitis

A form of PERITONITIS seen in patients with TUBERCULOSIS, characterized by lesion either as a miliary form or as a pelvic mass on the peritoneal surfaces. Most patients have ASCITES, abdominal swelling, ABDOMINAL PAIN, and other systemic symptoms such as FEVER; WEIGHT LOSS; and ANEMIA.

Also Known As:

Networked: 263 relevant articles (12 outcomes, 16 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Ascites
2.	Tuberculosis (Tuberculoses)
3.	Carcinoma (Carcinomatosis)
4.	Pancreatitis
5.	Peritonitis

Experts

1.	Akpolat, Tekin: 3 articles (08/2013 - 09/2003)
2.	Kim, Sun-Mi: 2 articles (04/2015 - 06/2011)
3.	Lee, Sang-Oh: 2 articles (04/2015 - 06/2011)
4.	Kim, Yang Soo: 2 articles (04/2015 - 06/2011)
5.	Park, Su-Jin: 2 articles (04/2015 - 06/2011)
6.	Kim, Sung-Han: 2 articles (04/2015 - 06/2011)
7.	Woo, Jun Hee: 2 articles (04/2015 - 06/2011)
8.	Choi, Sang-Ho: 2 articles (04/2015 - 06/2011)
9.	Sevinc, Alper: 2 articles (03/2006 - 10/2002)
10.	Hsu, K T: 2 articles (04/2005 - 08/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tuberculous Peritonitis:

1.	Adenosine DeaminaseIBA 07/01/1992 - "The aim of this study was to confirm that ascitic fluid determination of adenosine deaminase activity (ADA) is useful for the diagnosis of tuberculous peritonitis. " 04/01/2015 - "A rapid and non-invasive 2-step algorithm for diagnosing tuberculous peritonitis using a T cell-based assay on peripheral blood and peritoneal fluid mononuclear cells together with peritoneal fluid adenosine deaminase." 12/01/2014 - "Role of ascitic fluid adenosine deaminase (ADA) and serum CA-125 in the diagnosis of tuberculous peritonitis." 08/30/2013 - "Diagnostic accuracy of adenosine deaminase for tuberculous peritonitis: a meta-analysis." 04/01/2012 - "Use of adenosine deaminase measurements and QuantiFERON in the rapid diagnosis of tuberculous peritonitis."
2.	Rifampin (Rifampicin)FDA LinkGeneric 07/01/2003 - "On the contrary, for the treatment of tuberculous peritonitis, oral rifampin therapy is not expected to be effective because of its low peritoneal fluid concentration." 05/01/2001 - "Triple therapy without rifampicin for 6 months is sufficient to treat tuberculous peritonitis." 05/01/2001 - "To evaluate the clinical presentation, biochemical (ascites and serum) and laparoscopic findings, and to assess the efficacy of triple antituberculous therapy without rifampicin for 6 months in patients with tuberculous peritonitis. " 07/01/2006 - "After the administration of rifampin, serum TSH increased to 170 mU/l; B) Patient 2: a peritoneal-biopsy specimen containing Langhans' giant cells led to a diagnosis of tuberculous peritonitis in a 66-yr-old woman with ascites. " 01/01/2015 - "Here, we report a case of peritoneal tuberculosis which was successfully treated with a non-rifampin based regimen in tandem with ongoing administration of a tyrosine kinase inhibitor, dasatinib, for CML. "
3.	tributyl phosphate (TBP)IBA 04/01/2015 - "A recently developed RD-1 gene-based assay for diagnosing tuberculous peritonitis (TBP) has given promising results. " 06/01/2005 - "The purpose of the present study was to investigate the diagnostic features of 39 patients hospitalized with tuberculous peritonitis (TBP) in Dicle University Hospital, Turkey between January 1994 and August 2003. " 05/01/2013 - "To evaluate the value of T-SPOT.TB in the diagnosis of tuberculous peritonitis (TBP). " 11/01/2011 - "Despite recent progress, the fast and accurate diagnosis of tuberculous peritonitis (TBP) continues to be a challenge, mainly because of the lack of specific clinical features and the difficulty in isolating the M. " 06/01/2011 - "The utility of a newly-developed Mycobacterium tuberculosis-specific enzyme-linked immunosorbent spot (ELISPOT) assay for diagnosis of tuberculous peritonitis (TBP) has not been fully assessed. "
4.	Isoniazid (Ftivazide)FDA LinkGeneric 06/01/1955 - "Isoniazid in tuberculous peritonitis of childhood." 06/28/1953 - "[Successful isoniazid therapy of tumorous peritoneal tuberculosis]." 01/01/1979 - "A patient with tuberculous peritonitis is presented with a diagnostic problem, because of continuous and spiking fever, while she was on isoniazid. " 01/01/1954 - "[Excellent results of isoniazid therapy of a case of peritoneal tuberculosis with pulmonary tuberculosis]." 01/01/2014 - "An 86-year-old woman who had been treated for tuberculous peritonitis and pulmonary tuberculosis, exhibited a disturbance of consciousness and tonic-clonic convulsions seven days after the administration of the antituberculous drug isoniazid. "
5.	Interferon-gamma (Interferon, gamma)IBA 03/14/2013 - "Assessment by meta-analysis of interferon-gamma for the diagnosis of tuberculous peritonitis." 09/01/1991 - "Gamma interferon concentration was higher in tuberculous peritonitis than in the other causes of ascites (p less than 0.0001), and a cut-off between 3 and 9 u/ml reached a sensitivity and a specificity of 100%. " 09/01/1991 - "Diagnostic value of ascites gamma interferon levels in tuberculous peritonitis. " 03/14/2013 - "To investigate the performance and diagnostic accuracy of interferon-gamma (IFN-γ) for tuberculous peritonitis (TBP) by meta-analysis. " 03/01/1999 - "To evaluate the diagnostic potential of the ADA(T), ADA isoenzymes (ADA1 and ADA2) and the interferon-gamma (IFN-gamma) test in HIV-seropositive patients with tuberculous peritonitis. "
6.	PyrazinamideFDA LinkGeneric 02/01/2007 - "Anti-peritoneal tuberculosis treatment with rifampin, isoniazid and pyrazinamide was started. " 10/15/2005 - "Based on a systematic review of the literature, we recommend: tuberculous peritonitis should be considered in the differential diagnosis of all patients presenting with unexplained lymphocytic ascites and those with a serum-ascites albumin gradient (SAAG) of <11 g/L; culture growth of Mycobacterium of the ascitic fluid or peritoneal biopsy as the gold standard test; further studies to determine the role of polymerase chain reaction, ascitic adenosine deaminase and the BACTEC radiometric system for acceleration of mycobacterial identification as means of improving the diagnostic yield; increasing utilization of ultrasound and computerized tomographic scan for the diagnosis and as a guidance to obtain peritoneal biopsies; low threshold for diagnostic laparoscopy; treatment for 6 months with the first-line antituberculous drugs (isoniazid, rifampicin, ethambutol and pyrazinamide) in uncomplicated cases."
7.	Ethambutol (Myambutol)FDA LinkGeneric 10/01/2012 - "Treatment by rifampicin, isoniazid and ethambutol for tuberculous peritonitis was started then halted because of drug-induced liver injury. " 10/15/2005 - "Based on a systematic review of the literature, we recommend: tuberculous peritonitis should be considered in the differential diagnosis of all patients presenting with unexplained lymphocytic ascites and those with a serum-ascites albumin gradient (SAAG) of <11 g/L; culture growth of Mycobacterium of the ascitic fluid or peritoneal biopsy as the gold standard test; further studies to determine the role of polymerase chain reaction, ascitic adenosine deaminase and the BACTEC radiometric system for acceleration of mycobacterial identification as means of improving the diagnostic yield; increasing utilization of ultrasound and computerized tomographic scan for the diagnosis and as a guidance to obtain peritoneal biopsies; low threshold for diagnostic laparoscopy; treatment for 6 months with the first-line antituberculous drugs (isoniazid, rifampicin, ethambutol and pyrazinamide) in uncomplicated cases."
8.	butyl 3-(1H-tetrazol-5-yl)oxanilate (MTB)IBA 09/01/2015 - "The present study aimed at assessing efficacy of Xpert™ MTB/Rif assay for diagnosing peritoneal tuberculosis. " 09/01/2015 - "Tissue Xpert™ MTB/Rif assay was of limited use in diagnosing peritoneal tuberculosis." 09/01/2015 - "Thus, sensitivity, specificity, positive, and negative predictive values for tissue Xpert™ MTB/Rif assay in diagnosing peritoneal tuberculosis were 19 % (95 % C.I: 6 % to 42 %), 100 % (95 % C.I: 59 % to 100 %), 100 % (40 % to 100 %), and 29 % (95 % C.I: 13 % to 51 %), respectively. " 09/01/2015 - "Xpert™ MTB/Rif assay was positive in 4/21 patients with peritoneal tuberculosis and in none of the 7 patients with alternative diagnosis. " 01/01/2009 - "Peritoneal tuberculosis is a very rare manifestation of MTB with subtle clinical findings that may result in a significant diagnostic delay, often of more than four months. "
9.	Proteins (Proteins, Gene)IBA 04/01/1993 - "The albumin ascites serum gradient and total proteins separate the ascites ascites caused by portal hypertension from the neoplastic ascites and peritoneal tuberculosis. " 03/01/1994 - "Although the ascitic fluid concentrations of these proteins or protein-bound substances tend to be quite high in patients with peritoneal carcinomatosis and low in the setting of cirrhotic ascites, the problem is that patients with tuberculous peritonitis, cardiac ascites, pancreatitis ascites, etc. usually have values in the malignancy range, i.e., false-positive results. " 01/01/1995 - "Ascitic fluid pH, lactate, total proteins, cell count, lactate dehydrogenase, glucose, and their blood-ascitic gradients were determined in 10 patients with tuberculous peritonitis (group I). "
10.	tebufenozide (Mimic)IBA 12/01/2010 - "Peritoneal tuberculosis may mimic a pelvic mass in imaging studies and also may increase CA-125 levels. " 04/01/2009 - "More attention should be paid to peritoneal tuberculosis, which can markedly accumulate (18)F-FDG and mimic peritoneal carcinoma." 02/01/2007 - "Peritoneal tuberculosis can mimic advanced stage ovarian cancer and can lead to the performance of an unnecessary extended surgery. " 01/01/2006 - "It is well known that peritoneal tuberculosis may mimic advanced-stage epithelial ovarian carcinoma because of similar clinical, radiologic, and laboratory findings. " 10/01/2005 - "The disease may mimic peritoneal tuberculosis or carcinomatosis intra-operatively. "

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 11/01/1975 - "Good results are obtained with chemotherapy in both intestinal and peritoneal tuberculosis. " 03/01/2005 - "This report is of a case of tuberculous peritonitis that developed during antituberculous chemotherapy. " 06/01/2003 - "With the introduction of effective antituberculous chemotherapy, the clinical outcome of tuberculous peritonitis depends much on the diagnostic accuracy of this disease entity. " 01/01/1992 - "We conclude that, although target biopsy is an effective method of obtaining an early diagnosis of peritoneal tuberculosis, chemotherapy may be started on the basis of visual laparoscopic appearances alone." 02/01/1962 - "Tuberculous peritonitis in the chemotherapy ear."
2.	Continuous Ambulatory Peritoneal Dialysis (CAPD) 01/01/2002 - "Further studies are required to determine the sensitivity and specificity of the technique in CAPD patients with tuberculous peritonitis." 08/01/2013 - "There were eleven patients (2.6 %) with tuberculous peritonitis among 414 CAPD patients. " 08/01/2013 - "A retrospective study of CAPD patients with tuberculous peritonitis was done. " 08/01/2013 - "Mycobacterium tuberculous peritonitis in CAPD patients: a report of 11 patients and review of literature." 07/01/2011 - "Polymerase chain reaction can play an important role in the diagnosis of tuberculous peritonitis in patients undergoing CAPD."
3.	Laparotomy 01/01/1911 - "Severe Tuberculous Peritonitis in a Girl cured by Laparotomy." 01/01/2013 - "When these tests are negative or unavailable then diagnostic laparoscopy or laparotomy should be performed with the aid of frozen section to avoid unnecessary radical surgery in cases of peritoneal tuberculosis." 06/01/2008 - "Exploratory laparotomy showed multiple peritoneal implants, and a diagnosis of peritoneal tuberculosis was obtained from local biopsy. " 07/01/2006 - "They underwent emergency laparotomy which led to diagnosis of peritoneal tuberculosis by histopathological analysis of peritoneal biopsies. " 10/01/2005 - "Excisional biopsy taken from the peritoneum during laparotomy resulted in the histopathologic diagnosis of tuberculous peritonitis. "
4.	Catheters 01/01/1999 - "Treatment of tuberculous peritonitis consists in removing the peritoneal catheter and initiating antituberculosis medications, though the dosage and duration of antituberculosis medication are not yet well defined. " 02/01/1989 - "Tuberculous peritonitis in a CAPD patient cured without catheter removal: case report, review of the literature, and guidelines for treatment and diagnosis." 08/01/2013 - "Based on the analysis of all published reports of tuberculous peritonitis, there was no significant difference in patient survival between patients in whom CAPD catheter was removed or retained. " 08/01/2013 - "The aims of the present report were to document our experience of the prevalence of tuberculous peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients, mode of presentation, diagnosis and outcome and to discuss the current published data about catheter removal. " 01/01/1991 - "Although conventional wisdom advises removal of the Tenckhoff catheter as part of the therapy for tuberculous peritonitis, there are a few recent reports of cases successfully treated while maintaining the patients on CAPD. "
5.	Directly Observed Therapy 09/01/2015 - "There was no difference in efficacy of antituberculosis therapy delivered for either 6 months or 9 months in either gastrointestinal or peritoneal tuberculosis, confirming the efficacy of intermittent directly observed therapy. "