Hepatic Tuberculosis

Infection of the LIVER with species of MYCOBACTERIUM, most often MYCOBACTERIUM TUBERCULOSIS. It is characterized by localized small tuberculous miliary lesions or tumor-like mass (TUBERCULOMA), and abnormalities in liver function tests.

Also Known As:

Networked: 26 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Carcinoma (Carcinomatosis)
2.	Hepatocellular Carcinoma (Hepatoma)
3.	Neoplasm Metastasis (Metastasis)
4.	Chronic Hepatitis C
5.	Chronic Hepatitis B

Experts

1.	Park, Jeong-Ik: 1 article (08/2015)
2.	Yazici, H: 1 article (01/2015)
3.	Sever, M S: 1 article (01/2015)
4.	Moosa, Mahomed-Yunus S: 1 article (01/2015)
5.	Gounder, Lilishia: 1 article (01/2015)
6.	Gulluoglu, M: 1 article (01/2015)
7.	Caliskan, B: 1 article (01/2015)
8.	Turkmen, A: 1 article (01/2015)
9.	Hickey, Andrew J: 1 article (01/2015)
10.	Caliskan, Y: 1 article (01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hepatic Tuberculosis:

1.	Tuberculin (PPD)IBA 12/01/1984 - "Hepatic tuberculosis was considered most likely because, after operation, an intermediate-strength purified protein derivative (PPD) skin test gave strongly positive results and his subsequent response to antituberculous treatment was excellent. "
2.	tebufenozide (Mimic)IBA 09/01/2009 - "Primary hepatic tuberculosis in an immunocompetent patient: the Great Mimic." 01/01/2014 - "Imaging studies for hepatic tuberculosis are nonspecific and mimic primary or metastatic carcinoma. "
3.	Sulfur HexafluorideIBA 06/01/2010 - "The purposes of this study were to describe the ultrasonographic findings in hepatic tuberculosis (TB) after administration of a second-generation sulfur hexafluoride-filled microbubble contrast agent and to correlate these findings with pathologic characteristics. "
4.	Carbon MonoxideIBA 01/01/2015 - "A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection." 08/01/2014 - "Co-existence of hepatocellular carcinoma and hepatic tuberculosis." 01/01/2012 - "The development of jaundice after initiation of HAART in HIV-TB co-infected patients is a challenging presentation in resource constrained settings, and is often attributed to drug induced liver injury (DILI).Some investigators have described hepatic tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) as a cause of liver disease in patients initiating HAART, which could also cause jaundice. "
5.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 06/01/2014 - "Hepatic tuberculosis mimics metastasis revealed by 18F-FDG PET/CT." 01/01/2014 - "Multiple hepatic lesions in a case of isolated hepatic tuberculosis simulating metastases on 18F-FDG PET/CT imaging."
6.	Alkaline PhosphataseIBA 01/01/1992 - "We believe this is the first case recorded in the English language literature of isolated hepatic tuberculosis manifesting first as an incidentally elevated alkaline phosphatase. " 01/01/1992 - "We describe a 40-year-old black North American woman with isolated hepatic tuberculosis and an incidentally elevated alkaline phosphatase. " 01/01/1995 - "Since there is no consistent clinical pattern in patients with hepatic tuberculosis, the diagnosis should be considered in patients with unexplained fever associated especially with hepatomegaly or hepatosplenomegaly, elevated alkaline phosphatase level, hypergrammaglobulinaemia and increased ESR, Liver biopsy is the most valuable method to confirm the diagnosis of hepatic tuberculosis."
7.	ruberythric acid (AlP)IBA 01/01/1995 - "The biochemical tests suggesting hepatic tuberculosis were reversed A/G ratio and disproportionate elevation of ALP." 06/01/2003 - "Fever, weight loss, hepatomegaly, disproportionate elevation of ALP and reverse A/G ratio were common in hepatic tuberculosis. "
8.	GlycogenIBA 06/01/1965 - "Carbohydrate metabolism in experimental tuberculosis: hepatic enzymes related to glycogen metabolism & synthesis of glycogen from labelled glucose."
9.	Glucose (Dextrose)FDA LinkGeneric 06/01/1965 - "Carbohydrate metabolism in experimental tuberculosis: hepatic enzymes related to glycogen metabolism & synthesis of glycogen from labelled glucose."
10.	Ethiodized Oil (Ethiodol)FDA Link 03/01/1989 - "We present a case of the solitary hepatic tuberculosis, of which angiographic findings originally suggested hepatocellular carcinoma (HCC) given Lipiodol Ultra Fluid (LUF). "

Therapies and Procedures

1.	Laparotomy 01/01/2004 - "The diagnosis of hepatic tuberculosis is generally done in the intraoperative or postoperative period by analyzing a specimen taken by laparoscopy or laparotomy during the study of a hepatic mass. " 09/01/1956 - "[Hepatic tuberculosis of nodular type; detection during laparotomy]."
2.	Microbubbles 06/01/2010 - "The purposes of this study were to describe the ultrasonographic findings in hepatic tuberculosis (TB) after administration of a second-generation sulfur hexafluoride-filled microbubble contrast agent and to correlate these findings with pathologic characteristics. "
3.	Transplantation (Transplant Recipients) 01/01/2015 - "In this report, we present our experience in transplantation for a patient with CGD complicated by isolated hepatic tuberculosis abscess. " 01/01/2013 - "The renal post-transplantation patient with hepatic tuberculosis eventually died of multiple organ failure (MODS). " 12/31/2004 - "Indications for A-A LDLT were: chronic hepatitis B (309), chronic hepatitis C (18), hepatocellular carcinoma (144), alcoholic cirrhosis (20), Wilson's disease (4), autoimmune hepatitis (4), hepatic tuberculosis (1), cholangiocarcinoma (2), cryptogenic cirrhosis (5), secondary biliary cirrhosis (7), primary biliary cirrhosis (2), fulminant hepatic failure (18), primary sclerosing cholangitis (2), vanishing bile duct syndrome (1) and re-transplantation (4). "
4.	Highly Active Antiretroviral Therapy (HAART) 01/01/2012 - "The development of jaundice after initiation of HAART in HIV-TB co-infected patients is a challenging presentation in resource constrained settings, and is often attributed to drug induced liver injury (DILI).Some investigators have described hepatic tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) as a cause of liver disease in patients initiating HAART, which could also cause jaundice. "
5.	Transplants (Transplant) 10/01/2002 - "Indications for A-A LDLT were: chronic hepatitis B (203), chronic hepatitis C (5), hepatocellular carcinoma (64), alcoholic cirrhosis (9), cryptogenic cirrhosis (4), secondary biliary cirrhosis (5), primary biliary cirrhosis (1), Wilson' s disease (2), autoimmune hepatitis (1), hepatic tuberculosis (1), cholangiocarcinoma (1), fulminant hepatic failure (14) and primary non-function of cadaveric liver graft (1). "