Hepatic Tuberculosis

Infection of the LIVER with species of MYCOBACTERIUM, most often MYCOBACTERIUM TUBERCULOSIS. It is characterized by localized small tuberculous miliary lesions or tumor-like mass (TUBERCULOMA), and abnormalities in liver function tests.

Also Known As:

Networked: 27 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency)
2.	Fibrosis (Cirrhosis)
3.	Neoplasm Metastasis (Metastasis)
4.	Hepatocellular Carcinoma (Hepatoma)
5.	Fever (Fevers)

Experts

1.	Chhanchure, Utkarsh: 1 article (04/2022)
2.	Deodhar, Kedar: 1 article (04/2022)
3.	Kale, Aditya: 1 article (04/2022)
4.	Kulkarni, Suyash: 1 article (04/2022)
5.	Mehta, Shaesta: 1 article (04/2022)
6.	Patil, Prachi S: 1 article (04/2022)
7.	Tandon, Sandeep: 1 article (04/2022)
8.	Caliskan, B: 1 article (01/2015)
9.	Caliskan, Y: 1 article (01/2015)
10.	Gulluoglu, M: 1 article (01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hepatic Tuberculosis:

1.	Tuberculin (PPD)IBA 12/01/1984 - "Hepatic tuberculosis was considered most likely because, after operation, an intermediate-strength purified protein derivative (PPD) skin test gave strongly positive results and his subsequent response to antituberculous treatment was excellent. "
2.	Proteins (Proteins, Gene)FDA Link 12/01/1984 - "Hepatic tuberculosis was considered most likely because, after operation, an intermediate-strength purified protein derivative (PPD) skin test gave strongly positive results and his subsequent response to antituberculous treatment was excellent. "
3.	Sulfur HexafluorideIBA 06/01/2010 - "The purposes of this study were to describe the ultrasonographic findings in hepatic tuberculosis (TB) after administration of a second-generation sulfur hexafluoride-filled microbubble contrast agent and to correlate these findings with pathologic characteristics. "
4.	PorphyrinsIBA 08/01/1983 - "A patient with cavitary tuberculosis, hepatic cirrhosis, bullous skin lesions over sun-exposed surfaces, disorientation, and a chronic, as well as recent, history of illicit alcohol consumption was found to have acute variegate porphyria by characteristic fecal and urinary porphyrin studies. "
5.	Contrast MediaIBA 06/01/2010 - "The purposes of this study were to describe the ultrasonographic findings in hepatic tuberculosis (TB) after administration of a second-generation sulfur hexafluoride-filled microbubble contrast agent and to correlate these findings with pathologic characteristics. "
6.	4-trifluoromethylsalicylic acid (HTB)IBA 04/01/2022 - "Hepatic tuberculosis (HTB) is rare and mimics neoplastic liver lesions clinico-radiologically leading to misdiagnosis and even unnecessary surgery. " 01/01/2022 - "To understand the clinical and imaging manifestations and the treatment and follow-up of hepatic tuberculosis (HTB), we retrospectively analysed the clinical and imaging data of 29 patients with HTB who had been diagnosed clinically or by biopsy, and the clinical and imaging data had been summarised. " 01/01/2014 - "Hepatic tuberculosis (HTB) is commonly encountered in patients with widespread miliary disease. " 09/01/2023 - "Hepatic tuberculosis (HTB) is an uncommon manifestation of tuberculous infections, and there has been no proven causal link between HTB and hepatocellular carcinoma (HCC). "
7.	AcidsIBA 04/01/2023 - "An eventual liver biopsy identified acid-fast bacilli, confirming a diagnosis of hepatic tuberculosis. " 07/01/2004 - "Our results suggest that hepatic tuberculosis is more common in AIDS than previously recognized, and that liver specimens should be examined routinely for the presence of acid-fast bacilli." 01/01/1999 - "Case one, the macronodular type of hepatic tuberculosis, presented as pyrexia of unknown origin and was eventually diagnosed by sectional imaging when a mass lesion developed in the liver and aspiration revealed acid-fast bacilli. "
8.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 06/01/2014 - "Hepatic tuberculosis mimics metastasis revealed by 18F-FDG PET/CT." 01/01/2014 - "Multiple hepatic lesions in a case of isolated hepatic tuberculosis simulating metastases on 18F-FDG PET/CT imaging."
9.	Alkaline PhosphataseIBA 01/01/1992 - "We believe this is the first case recorded in the English language literature of isolated hepatic tuberculosis manifesting first as an incidentally elevated alkaline phosphatase. " 01/01/1992 - "We describe a 40-year-old black North American woman with isolated hepatic tuberculosis and an incidentally elevated alkaline phosphatase. " 01/01/1995 - "Since there is no consistent clinical pattern in patients with hepatic tuberculosis, the diagnosis should be considered in patients with unexplained fever associated especially with hepatomegaly or hepatosplenomegaly, elevated alkaline phosphatase level, hypergrammaglobulinaemia and increased ESR, Liver biopsy is the most valuable method to confirm the diagnosis of hepatic tuberculosis."
10.	ParaproteinsIBA 05/31/1969 - "[Hepatic tuberculosis with myelomatous like paraprotein]."

Therapies and Procedures

1.	Laparotomy 01/01/2004 - "The diagnosis of hepatic tuberculosis is generally done in the intraoperative or postoperative period by analyzing a specimen taken by laparoscopy or laparotomy during the study of a hepatic mass. " 09/01/1956 - "[Hepatic tuberculosis of nodular type; detection during laparotomy]."
2.	Microbubbles 06/01/2010 - "The purposes of this study were to describe the ultrasonographic findings in hepatic tuberculosis (TB) after administration of a second-generation sulfur hexafluoride-filled microbubble contrast agent and to correlate these findings with pathologic characteristics. "
3.	Transplantation 01/01/2015 - "In this report, we present our experience in transplantation for a patient with CGD complicated by isolated hepatic tuberculosis abscess. " 01/01/2013 - "The renal post-transplantation patient with hepatic tuberculosis eventually died of multiple organ failure (MODS). " 12/31/2004 - "Indications for A-A LDLT were: chronic hepatitis B (309), chronic hepatitis C (18), hepatocellular carcinoma (144), alcoholic cirrhosis (20), Wilson's disease (4), autoimmune hepatitis (4), hepatic tuberculosis (1), cholangiocarcinoma (2), cryptogenic cirrhosis (5), secondary biliary cirrhosis (7), primary biliary cirrhosis (2), fulminant hepatic failure (18), primary sclerosing cholangitis (2), vanishing bile duct syndrome (1) and re-transplantation (4). "
4.	Therapeutics 10/15/1999 - "The therapy of hepatic tuberculosis follows the guidelines of systemic tuberculostatic therapy according to other presentations of this disease. " 04/01/2010 - "We describe a 54-y-old female with hepatic tuberculosis and worsening hepatitis after initiation of anti-tuberculosis therapy. " 04/01/2010 - "The role of corticosteroid therapy in addition to anti-tuberculous agents in the treatment of hepatic tuberculosis is unclear. "
5.	Highly Active Antiretroviral Therapy (HAART) 10/14/2012 - "The development of jaundice after initiation of HAART in HIV-TB co-infected patients is a challenging presentation in resource constrained settings, and is often attributed to drug induced liver injury (DILI).Some investigators have described hepatic tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) as a cause of liver disease in patients initiating HAART, which could also cause jaundice. "