Bovine Tuberculosis

02/25/2006 - "Prospects for the development of improved vaccines against bovine tuberculosis are promising and vaccination approaches could become very valuable in the control and eradication of bovine tuberculosis."
03/05/2014 - "Comparison of the immunogenicity and protection against bovine tuberculosis following immunization by BCG-priming and boosting with adenovirus or protein based vaccines."
08/01/2009 - "Viral booster vaccines improve Mycobacterium bovis BCG-induced protection against bovine tuberculosis."
05/01/2003 - "bovis and against other intracellular parasites continue to be found and discoveries from vaccine studies on bovine tuberculosis may provide helpful insights into requirements for vaccines against other intracellular pathogens."
03/30/2012 - "bovis has led to renewed interest in the use of vaccines for the control of bovine tuberculosis (TB). "

12/01/2008 - "Efforts to develop a better diagnostic assay for bovine tuberculosis have shown that the sensitivity and specificity of an assay can be improved by the use of two or more antigens. "
01/01/2004 - "In a field trials to using reMPB70 antigen for the serodiagnosis of bovine tuberculosis using ELISA test. "
01/01/1999 - "The results of the study indicate that of the four antigens tested in the IFN-gamma assay, only ESAT-6 would be suitable for differentiating BCG-vaccinated animals from those infected with bovine tuberculosis."
03/21/1998 - "The study has provided a clearer understanding of the kinetics of antibody responses to defined mycobacterial antigens at the subclass level in bovine tuberculosis and has made it possible to develop a novel ELISA system which may be useful in disease diagnosis."
03/01/1998 - "The aim of this study was to identify a common mycobacterial antigen which was recognized in bovine tuberculosis and to characterize the response to this antigen at the epitope level. "

02/01/2010 - "Field evaluation of the protective efficacy of Mycobacterium bovis BCG vaccine against bovine tuberculosis."
11/01/2008 - "Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine delivered to calves by the subcutaneous (s.c.) or by the oral route in a formulated lipid matrix has been previously shown to induce similar levels of protection against bovine tuberculosis. "
04/01/2003 - "The Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine has variable efficacy for both human and bovine tuberculosis. "
08/01/1997 - "The enhanced immune responses and protection against bovine tuberculosis observed in the intraduodenally BCG-vaccinated possums indicated that if BCG vaccine is protected from degradation in the stomach its efficacy should improve."
08/01/1997 - "An effective oral bacille Calmette-Guérin (BCG) vaccine would have advantages for use in humans and as an oral bait vaccine for protecting wild-life against bovine tuberculosis. "

01/01/2012 - "The aim of this study was to obtain epidemiological estimates of bovine tuberculosis (TB) prevalence in cattle in the highlands of Cameroon using two population-based tuberculin skin test (TST) surveys in the years 2009 and 2010. "
12/01/2008 - "The study was conducted to determine the status of bovine tuberculosis in Addis Ababa, Ethiopia, by a comparative intradermal tuberculin test of 1,869 animals in 106 farms. "
10/01/2008 - "A study to determine the prevalence of bovine tuberculosis in the transhumant and agro-pastoral cattle herds in the border areas of Katakwi and Moroto districts in Uganda was carried out from July 2006 to January 2007 using comparative intradermal tuberculin test containing bovine and avian PPDs. "
06/01/2006 - "In the present study, ADA seric activity was evaluated comparatively to the comparative tuberculin test in the diagnosis of bovine tuberculosis. "
05/03/2001 - "A secondary aim in the study was to assess the ESAT-6 and PPD-based tests for detecting bovine tuberculosis in skin test-negative animals from a persistently infected herd. "

06/10/2003 - "Improved immunogenicity of DNA vaccination with mycobacterial HSP65 against bovine tuberculosis by protein boosting."
10/01/2012 - "Prevalence of bovine tuberculosis in slaughter cattle in Kenya: a postmortem, microbiological and DNA molecular study."
01/31/2006 - "The results were expected to lay foundation for further studies on the subunit vaccine and DNA vaccine of MPB83 gene in their prevention against bovine tuberculosis."
04/01/2005 - "The results are expected to lay foundation for further studies on the subunit vaccine and DNA vaccine of MPB51 gene in their prevention of bovine tuberculosis."
01/01/2015 - "The proportion of MTC DNA positive samples was higher in the bovine tuberculosis-infected than in presumed negative area (0.32 and 0.18, respectively). "

01/01/2014 - "Therefore, analysis of the proteins responsible for cell invasion will assist clinicians in combating bovine tuberculosis. "
11/01/2013 - "Previous experiments for the identification of novel diagnostic or vaccine candidates for bovine tuberculosis have followed a targeted approach, wherein specific groups of proteins suspected to contain likely candidates are prioritized for immunological assessment (for example, with in silico approaches). "
06/01/2009 - "T-cell responses and antibody responses to these proteins have been extensively explored for sensitive and specific diagnosis of bovine tuberculosis."
06/01/2006 - "The use of specific proteins (e.g., ESAT-6, CFP-10, and MPB83), however, generally enhances the specificity of bovine tuberculosis tests. "
11/01/2004 - "In conclusion, the use of CyaA fusion proteins with ESAT-6 and CFP10 has the potential to improve the sensitivity of immunodiagnostic tests detecting bovine tuberculosis in cattle."

10/01/2006 - "In the search for improved tools with which to control bovine tuberculosis, the development of enhanced immunodiagnostic reagents is a high priority. "
07/01/1998 - "Defined antigenic reagents and knowledge of T-cell responses are required for the design of improved diagnostic tests for bovine tuberculosis. "
06/15/2005 - "This study supported restricted species distribution of these genes as well as identifying a different range of MOTT species that could be included in specificity testing of new diagnostic reagents for bovine tuberculosis."
06/15/2005 - "Elucidation of the MOTT species was to facilitate specificity testing of new and existing diagnostic test reagents for bovine tuberculosis. "
07/05/2011 - "The urgency for new and improved cattle vaccines and diagnostic reagents for Bovine tuberculosis (TB) has made their development a research priority in Great Britain (GB). "

09/01/2003 - "A DNA prime-Mycobacterium bovis BCG boost vaccination strategy for cattle induces protection against bovine tuberculosis."
04/01/2003 - "A DNA prime-live vaccine boost strategy in mice can augment IFN-gamma responses to mycobacterial antigens but does not increase the protective efficacy of two attenuated strains of Mycobacterium bovis against bovine tuberculosis."
07/01/2005 - "The order of prime-boost vaccination of neonatal calves with Mycobacterium bovis BCG and a DNA vaccine encoding mycobacterial proteins Hsp65, Hsp70, and Apa is not critical for enhancing protection against bovine tuberculosis."
01/01/2003 - "To determine the ability of DNA vaccines, which express the mycobacterial antigens MPB83 and MPB70 and a DNA prime-protein boost strategy to stimulate immune responses in cattle and protect against bovine tuberculosis. "

08/01/2006 - "These results suggest that use of the prime-boost strategy offers better protection against bovine tuberculosis than does the combined DNA vaccines and BCG."
02/25/2009 - "Thus, combined DNA vaccines may provide enhanced immunotherapeutic efficacy for treatment of bovine tuberculosis."
06/10/2005 - "Our data indicate that combined DNA vaccines may be used in cattle to combat bovine tuberculosis."
01/01/2003 - "Vaccination of calves with MPB70 or MPB83 DNA vaccines or with a more immunogenic MPB70 DNA prime-protein boost strategy did not induce protection against bovine tuberculosis."
01/01/2003 - "Vaccination with DNA vaccines encoding MPB70 or MPB83 or a MPB70 DNA prime-protein boost does not protect cattle against bovine tuberculosis."

02/01/2013 - "The purpose of this study was to quantify co-mingling of elk and white-tailed deer (WTD) with cattle at multiple spatial scales (i.e., the regional farm scale and winter cattle feeding area patch) in southwestern Manitoba, Canada, to assess the potential for bovine tuberculosis transmission and identify alternative management strategies. "
07/01/2006 - "Assessment of diagnostic tools for eradication of bovine tuberculosis in cattle co-infected with Mycobacterium bovis and M. "
01/01/2006 - "A descriptive analysis, to investigate the potential risk factors that might have contributed to the increased incidence of bovine tuberculosis (BTB) herd-breakdowns in the reference area of Co. "
10/01/1998 - "A review of history and development of research and control of bovine tuberculosis is given on the occasion of Kurt Wagener's 100th birthday with special reference to his and his co-workers contributions to this subject. "
01/01/2014 - "Severity of bovine tuberculosis is associated with co-infection with common pathogens in wild boar."

05/20/2005 - "Oral administration of 10 pellets of lipid-formulated BCG to cattle induced a significant level of protection against bovine tuberculosis compared to that observed in non-vaccinated animals and this level was similar to that seen in the BCG subcutaneously vaccinated animals. "

10/01/1978 - "[Chemoprophylaxis of bovine tuberculosis]."
09/01/1965 - "[Chemoprophylaxis of bovine tuberculosis]."
01/01/1961 - "[Further experiments on the use of INH chemoprophylaxis in bovine tuberculosis]."

10/01/2006 - "To determine the effect of fertility control on the rate of transmission of bovine tuberculosis (Tb), caused by Mycobacterium bovis, in brushtail possums (Trichosurus vulpecula). "
10/01/2006 - "The effect of fertility control on the transmission of bovine tuberculosis in wild brushtail possums."
12/22/1997 - "However, the high cost of developing a suitable fertility control agent, combined with the welfare and conservation implications, are significant factors which should be taken into account when considering its possible use as a means of controlling bovine tuberculosis in badger populations in the UK."
12/22/1997 - "These results show that whilst fertility control would not be a successful strategy for the control of bovine tuberculosis in badgers if used alone, it could be effective if used with culling as part of an integrated strategy. "
12/22/1997 - "A spatial stochastic simulation model was used to assess the potential of fertility control, based on a yet-to-be-developed oral bait-delivered contraceptive directed at females, for the control of bovine tuberculosis in badger populations in south-west England. "

05/01/2001 - "Antigen recognition and immunomodulation by gamma delta T cells in bovine tuberculosis."

09/01/2005 - "Use of rMPB70 protein and ESAT-6 peptide as antigens for comparison of the enzyme-linked immunosorbent, immunochromatographic, and latex bead agglutination assays for serodiagnosis of bovine tuberculosis."