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Tropicamide

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One of the MUSCARINIC ANTAGONISTS with pharmacologic action similar to ATROPINE and used mainly as an ophthalmic parasympatholytic or mydriatic.

Also Known As:

Akorn Brand of Tropicamide; Alcon Brand of Tropicamide; Bournonville Brand of Tropicamide; Cahill May Roberts Brand of Tropicamide; Chauvin Brand of Tropicamide; Colircusi Tropicamida; Medical Ophthalmics Brand of Tropicamide; Minims Tropicamide; Mydral; Mydriafair; Mydriaticum; Mydrum; N-Ethyl-N-(4-pyridylmethyl)tropamide; N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide; Novartis Brand of Tropicamide; Ocu-Tropic; Ocumed Brand of Tropicamide; Ocusoft Brand of Tropicamide; Pharmafair Brand of Tropicamide; Rivex Brand of Tropicamide; Stulln Brand 1 of Tropicamide; Stulln Brand 2 of Tropicamide; Triaminic DM; Tropicacyl; Tropicamide Faure; Tropicamide Minims; Tropicamide Monofree; Tropicamide Monohydrochloride, (R)-Isomer; Tropicamide Monohydrochloride, (S)-Isomer; Tropicamide, (+-)-Isomer; Tropicamide, (R)-Isomer; Tropicamide, (S)-Isomer; Ocu Tropic; OcuTropic; Tropicamide Alcon Brand; Tropicamide Chauvin Brand; Tropicamide Novartis Brand; Tropicamide Ocumed Brand; Tropicamide Pharmafair Brand; Tropicamide Rivex Brand; Benzeneacetamide, N-ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)-

Networked: 208 relevant articles (13 outcomes, 24 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Pyridines: 41
    - Tropicamide: 208
      - phenyltrope: 1
      - N-ethyl-2-phenyl-N-(4-pyridylmethyl)prop-2-enamide

Experts

1.	Mutti, Donald O: 4 articles (08/2011 - 11/2002)
2.	Miyazaki, Yasunori: 3 articles (02/2005 - 10/2002)
3.	Tokuda, Kazuhiro: 3 articles (02/2005 - 10/2002)
4.	Kamei, Yuko: 3 articles (02/2005 - 10/2002)
5.	Hirowatari, Takao: 3 articles (02/2005 - 10/2002)
6.	Matsubara, Masao: 3 articles (02/2005 - 10/2002)
7.	Hyman, Leslie: 3 articles (07/2004 - 02/2002)
8.	Norton, Thomas T: 3 articles (07/2004 - 02/2002)
9.	Bersani, Francesco Saverio: 2 articles (07/2015 - 09/2013)
10.	Corazza, Ornella: 2 articles (07/2015 - 09/2013)

Related Diseases

1.	Mydriasis 12/01/2012 - "The aim of this study was to evaluate by serial measurements, pupil mydriasis produced by topical application of tropicamide 1% using a spray in a closed eye or instillation in an open eye in adult and elderly populations. " 03/01/2012 - "This study investigated the association of transient changes in intraocular pressure (IOP) with changes in the anterior chamber configuration in children after diagnostic mydriasis with 1% tropicamide. " 08/01/1995 - "The aim of this study was to investigate the effect of nasolacrimal occlusion on tropicamide-induced mydriasis. " 03/01/2015 - "Effect of mydriasis induced by topical 0.5% tropicamide instillation on the corneal biomechanical properties in healthy individuals measured by ocular response analyzer." 01/01/2015 - "Tropicamide is an antimuscarinic ophthalmic solution used to produce short-acting mydriasis and cycloplegia. "
2.	Alzheimer Disease (Alzheimer's Disease) 06/01/1997 - "Results of this study indicate that pupil measurement after instillation of tropicamide cannot be used as a reliable diagnostic test for Alzheimer's disease. " 06/01/1996 - "We performed a masked study involving 17 patients with Alzheimer's disease and 20 mentally healthy controls with respect to the pupillary response induced by tropicamide. " 07/01/2009 - "Intraocular tropicamide of 0.005% concentration was administered in 3 groups: Alzheimer's disease patients (n = 8, average age = 76 ± 5), non-Alzheimer's disease elderly (n = 6, average age = 65 ± 7), and young subjects (n = 8, average age = 28 ± 5). " 02/01/2008 - "Previous research demonstrated that it is possible to distinguish patients with probable Alzheimer's disease from age-matched controls based on an exaggerated pupil dilation response to dilute tropicamide. " 01/01/2006 - "Patients suffering from Alzheimer's disease (AD) may show increased sensitivity to tropicamide, a muscarinic cholinoceptor antagonist. "
3.	Refractive Errors (Refractive Error) 01/01/2012 - "The aim of the study was to evaluate changes in ocular refraction after 1% tropicamide and its efficacy in diagnosing refractive errors in preschool children. " 09/01/2014 - "Spherical equivalent of refractive error, AL, and ACD all positively shifted after cycloplegia with tropicamide. " 09/01/2014 - "Spherical equivalent of refractive error, AL, and ACD all positively shifted significantly at 30 minutes after application of 0.4% tropicamide (p < 0.0001 for each parameter measured). " 09/01/2014 - "Spherical equivalent of refractive error (SER), axial length (AL), corneal curvature (CC), and anterior chamber depth (ACD) were measured before and after 30 minutes from instillation of 0.4% tropicamide. " 01/01/2012 - "After the instillation of tropicamide, the spherical component of the refractive error significantly increased by +0.78 D, while the cylindrical component (i.e. "
4.	Cataract (Cataracts) 02/01/2009 - "When combined with 1 drop of tropicamide 1% preoperatively, both formulations provided safe and effective intracameral dilation for cataract surgery; however, the epi-S solution was the more efficacious at each step of the procedure." 01/01/2014 - "A total of 72 eyes of 72 patients scheduled to undergo cataract surgery were prospectively examined using the optical low-coherence reflectometry (OLCR) optical biometer before and after pupil dilation with tropicamide 1%. " 03/01/2000 - "Effect of tropicamide on aqueous flare before and after cataract surgery." 08/01/1998 - "After dilation with tropicamide 1%, lens opacities were graded using the Lens Opacities Classification System (LOCS) III. In this population of English men and women aged 64 to 74 years, most opacities were of the nuclear type. " 04/01/1996 - "The AL of one eye of 64 patients admitted for cataract surgery was measured before and after dilation with a drop of tropicamide 1%. "
5.	Glaucoma 09/01/2010 - "In total, 29 healthy individuals and 26 glaucoma patients underwent RNFL measurements with the Cirrus HD-OCT Model 4000 (Carl Zeiss Meditec Inc.) before and 30-40 min after pupil dilation with one drop of tropicamide 1%. " 01/01/1969 - "[Combined glaucoma provocation test with Mydriaticum-Roche and dark test with special reference to tonography]." 09/01/2011 - "Effects of unilateral topical administration of 0.5% tropicamide on anterior segment morphology and intraocular pressure in normal cats and cats with primary congenital glaucoma." 10/01/2000 - "Mydriasis with tropicamide alone is safe even in people with chronic glaucoma. " 10/01/2000 - "The risk of inducing acute glaucoma following mydriasis with tropicamide alone is close to zero, no case being identified. "

Related Drugs and Biologics

1.	Phenylephrine (Neo-Synephrine)
2.	Cyclopentolate (Cyclogyl)
3.	dapiprazole (Rev-Eyes)
4.	ibopamine
5.	Ophthalmic Solutions (Eye Drops)
6.	Retinaldehyde (Retinal)
7.	Fluorescein (Funduscein)
8.	Muscarinic Antagonists
9.	Oxygen
10.	Heroin (Diamorphine)

Related Therapies and Procedures

1.	Premedication
2.	Lenses
3.	Cataract Extraction
4.	Anesthesia
5.	Meridians (Jing Luo)