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Trinitrobenzenesulfonic Acid

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A reagent that is used to neutralize peptide terminal amino groups.

Also Known As:

2,4,6-Trinitrobenzene Sulfonate; Trinitrobenzenesulfonic Acid, Sodium Salt; Sulfonate, Trinitrobenzene; Picrylsulfonic Acid; Trinitrobenzene Sulfonate; Benzenesulfonic acid, 2,4,6-trinitro-

Networked: 217 relevant articles (15 outcomes, 34 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 58

Experts

1.	Zarzuelo, Antonio: 12 articles (07/2015 - 11/2002)
2.	Garrido-Mesa, Natividad: 6 articles (07/2015 - 05/2010)
3.	Martínez-Augustin, Olga: 6 articles (02/2015 - 05/2005)
4.	Dhaneshwar, Suneela S: 6 articles (10/2009 - 04/2007)
5.	Vadnerkar, Gaurav: 6 articles (10/2009 - 04/2007)
6.	Suárez, María Dolores: 5 articles (02/2015 - 05/2007)
7.	Ilan, Yaron: 5 articles (01/2015 - 09/2002)
8.	Gálvez, Julio: 5 articles (01/2014 - 11/2002)
9.	Kandpal, Mini: 5 articles (10/2009 - 04/2007)
10.	Algieri, Francesca: 4 articles (07/2015 - 01/2014)

Related Diseases

1.	Colitis 07/15/2007 - "The ameliorating effect of the azo conjugate and therapeutic efficacy of the carrier system was evaluated in trinitrobenzenesulfonic acid-induced experimental colitis model. " 06/01/2007 - "Therapeutic efficacy of the carrier system and the mitigating effect of the azo conjugate were evaluated in trinitrobenzenesulfonic acid-induced experimental colitis model. " 04/01/2007 - "Therapeutic efficacy of the carrier system and the mitigating effect of the azo conjugate were evaluated in trinitrobenzenesulfonic acid-induced experimental colitis model. " 11/01/2012 - "These pellets showed promising results in alleviating the conditions of an experimental model of colitis induced by trinitrobenzenesulfonic acid in rats." 08/01/2012 - "Protective effects of 3,4-oxo-isopropylidene-shikimic acid on experimental colitis induced by trinitrobenzenesulfonic acid in rats."
2.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/01/2013 - "The azo compound and the 4-aminophenylbenzoxazol-2-yl-5-acetic acid were evaluated for inflammatory bowel diseases, in trinitrobenzenesulfonic acid (TNB)-induced colitis in rats. " 05/01/2010 - "To evaluate the effect of live combined bifidobacterium, lactobacillus and enterococcus capsules for colitis in rats induced by trinitrobenzenesulfonic acid (TNBS), so as to explore a new therapy for inflammatory bowel diseases (IBD). " 01/01/2010 - "Inflammatory bowel disease was induced in Wistar albino rats by intrarectal administration of 2, 4, 6 trinitrobenzenesulfonic acid (TNBS, 0.25 ml 120 mg/ml in 50% ethanol intrarectally, on 1(st) day only). " 12/01/2010 - "Dietary polydextrose prevents inflammatory bowel disease in trinitrobenzenesulfonic acid model of rat colitis." 01/01/1996 - "The purpose of this study was to investigate the efficacy of alpha-linolenic acid-rich perilla oil emulsion (POE) in a rat model with trinitrobenzenesulfonic acid (TNB)-induced inflammatory bowel disease. "
3.	Ulcerative Colitis 04/01/2015 - "Protective effect of Lactobacillus plantarum 21, a probiotic on trinitrobenzenesulfonic acid-induced ulcerative colitis in rats." 01/01/2012 - "Finally the selected formulation was evaluated on trinitrobenzenesulfonic acid (TNBS) induced ulcerative colitis in rat model, in comparison with conventional UC treatments. " 10/01/2011 - "Rat model of ulcerative colitis was established by intra-colonic administration of trinitrobenzenesulfonic acid (TNBS). " 06/01/2001 - "Ulcerative colitis was induced in Lewis rats with trinitrobenzenesulfonic acid. " 10/07/2008 - "To evaluate the protective effects of ilomastat, an exogenous matrix metalloproteinase (MMP) inhibitor, on trinitrobenzenesulfonic acid (TNB)-induced ulcerative colitis (UC) in rats. "
4.	Hypersensitivity (Allergy) 10/15/1987 - "We have studied the influence of different degrees of calorie restriction on the induction and the regulation of the delayed type hypersensitivity (DTH) response to trinitrobenzenesulfonic acid (TNBS) and TNBS-modified spleen cells (TNBS-SC), injected by the sc or the iv route. " 10/15/1987 - "Calorie restriction modifies the delayed-type hypersensitivity response to the hapten trinitrobenzenesulfonic acid and to hapten-modified syngeneic spleen cells." 01/01/2006 - "Chronic hypersensitivity was observed in rats following spontaneous resolution of trinitrobenzenesulfonic acid-induced colitis. "
5.	Dermatitis 08/01/2007 - "Therefore, we also evaluated the efficacy of acetate in murine models of inflammatory diseases, and found that acetate administration (as well as administration of dexamethasone) attenuated trinitrobenzenesulfonic acid-induced colitis and dinitrofluorobenzene-induced dermatitis. "

Related Drugs and Biologics

1.	Dexamethasone (Maxidex)
2.	P-Glycoprotein
3.	alpha-Linolenic Acid (Linolenic Acid)
4.	Anti-Infective Agents (Microbicides)
5.	perilla seed oil
6.	Tablets
7.	Thalidomide (Thalomid)
8.	Dinitrofluorobenzene
9.	ilomastat
10.	Ethanol (Ethyl Alcohol)

Related Therapies and Procedures

1.	Rectal Administration
2.	Enema (Enemas)
3.	Nanospheres