Trichuriasis

05/05/1979 - " Mebendazole cured trichuriasis in 75% of the cases, and the overall egg reduction rate was 96%. "
07/01/1976 - "Thirty such children were investigated, and mebendazole was found to be safe and effective in the treatment of severe trichuriasis but it had to be given for a longer period than currently recommended. "
07/01/1982 - "Only mebendazole is effective against trichuriasis. "
01/01/1979 - "[Therapeutic efficacy of mebendazole in massive trichocephaliasis]."
03/01/1977 - "Mebendazole (methyl-5-benzoylbenzimidazole-2-carbamate), a new broad spectrum anthelmintic, cured 26 (74% out of 35 children) with severe symptomatic trichuriasis. "

01/01/2013 - "Growth reduction among primary schoolchildren with light trichuriasis in Malaysia treated with albendazole."
03/01/2009 - "Although the cure rate for treatment with albendazole was good, the low cure rate and egg reduction rate for trichuriasis needs to be considered."
02/01/1985 - "Albendazole, a broad spectrum anthelmintic, was administered as a 400 mg single dose to 20 patients harbouring Ascaris (ten cases), hookworms (four cases each of Ancylostoma duodenale and Necator americanus) and trichuriasis (ten cases). "
11/01/2004 - "Prolonged treatment with albendazole for massive trichuriasis infection."
02/01/1985 - "Ovicidal effects of albendazole in human ascariasis, ancylostomiasis and trichuriasis."

05/01/1951 - "[Application of hexylresorcinol in the treatment of ascaridosis and trichocephaliasis in children]."
01/01/1951 - "[Hexylresorcinol in the treatment of rectal trichocephaliasis]."
01/01/1952 - "[Treatment of trichocephaliasis with hexylresorcinol (santokin) in a form of enema; report of four cured cases]."
09/01/1951 - "[Nine cases of trichocephaliasis cured with hexylresorcinol enemas (santokin)]."
09/01/1951 - "[One hundred cases of trichocephaliasis cured with hexylresorcinol enemas (santokin)]."

07/01/1976 - "It is concluded that oxantel is a safe and effective anthelmintic for severe clinical trichuriasis."
01/01/1978 - "For trichuriasis, oxantel-pyrantel given twice, 12 hours apart, appears to be the best treatment schedule and further clinical trials using this regimen are suggested."
04/01/1982 - "[Massive trichocephaliasis and other helminthiasis in children and its treatment with pyrantel pamoate/oxantel]."
01/01/1978 - "In a pilot study in 17 children, oxantel-pyrantel as one single dose of 10 to 20mg/kg of each, gave good results in ascariasis but poor cure rates in both trichuriasis and necatoriasis. "
01/01/1978 - "204 individuals from a rural community were given a single dose of oxantel-pyrantel at 15mg/kg bodyweight and if still infected, 20mg/kg bodyweight, with cure rates of 100%, 53% and 71% for ascariasis, trichuriasis and hookworm infection, respectively. "

01/01/1978 - "For trichuriasis, oxantel-pyrantel given twice, 12 hours apart, appears to be the best treatment schedule and further clinical trials using this regimen are suggested."
10/03/1998 - "Randomised trial of albendazole and pyrantel in symptomless trichuriasis in children."
10/03/1998 - "Symptomless trichuriasis impairs growth and albendazole or pyrantel may affect growth, independently of a therapeutic action on parasites. "
01/01/1978 - "In a pilot study in 17 children, oxantel-pyrantel as one single dose of 10 to 20mg/kg of each, gave good results in ascariasis but poor cure rates in both trichuriasis and necatoriasis. "
01/01/1978 - "204 individuals from a rural community were given a single dose of oxantel-pyrantel at 15mg/kg bodyweight and if still infected, 20mg/kg bodyweight, with cure rates of 100%, 53% and 71% for ascariasis, trichuriasis and hookworm infection, respectively. "

01/01/1994 - "The authors point to high efficacy of the drugs mebendazol, albendazol, medaminol (against ancylostomiasis, ascariasis, trichocephaliasis), praziquantel (against schistosomiasis and hymenolepiasis)."
03/01/2002 - "Three randomized clinical studies were conducted in 2000 to evaluate the efficacy of nitazoxanide paediatric suspension compared to albendazole in the treatment of ascariasis and trichuriasis and praziquantel in the treatment of hymenolepiasis in children from Cajamarca, Peru. "
03/01/2002 - "Comparative clinical studies of nitazoxanide, albendazole and praziquantel in the treatment of ascariasis, trichuriasis and hymenolepiasis in children from Peru."
05/15/1987 - "Mebendazole can be used against numerous nematode-infections (Ascariasis, Trichuriasis, Oxyuriasis, Ancylostomiasis), Niclosamide against cestode-infections (Taeniasis, Hymenolepiasis, Diphyllobothriasis), whereas, Praziquantel is applied against trematode-infections."

01/01/2008 - "The present data indicate that the long-term control of onchocerciasis with ivermectin may provide additional health benefits by reducing infections with trichuriasis. "
11/01/2015 - "Periodic mass distribution of ivermectin had a significant impact on the prevalence of strongyloidiasis, less on trichuriasis and apparently no effect on ascariasis and hookworm infections."
07/01/1999 - "Single-dose treatment with the albendazole-ivermectin combination appears to be highly effective against trichuriasis and could prove valuable for routine use."
01/01/2014 - "Expanded use of albendazole in combination with ivermectin would ensure improved drug efficacies against trichuriasis and strongyloidiasis. "
01/01/2003 - "Because of the superiority of albendazole + ivermectin against both lymphatic filariasis and trichuriasis, this combination appears to be a suitable tool for the integrated or combined control of both public health problems."

11/01/1973 - "[Comparative study of the tolerance to and effectiveness of preparation G-665 and difezil in experimental trichocephaliasis and ganguleterakiasis in white mice]."
09/01/1991 - "[A comparative study of the efficacy of Vermox, albendazole and medamine in an experimental model of trichocephaliasis in mice]."
01/01/2004 - "Experiments have established the high efficacy of combinations of the micronized dosage form of trichlorophen, with albendazole or medamine in treating trichocephaliasis (its causative agent being Trichocephalus muris) in DBA/2st mice and that of trichlorophen in combination with azinox or fenasal in outbred albino mice with hymenolepiasis (its causative agent being Hymenolepis nana). "

01/01/2012 - "There is a pressing need to develop new anthelmintics against trichuriasis."
07/01/1994 - "The first group consisted on 72 intact animals, administered subcutaneous ivomek (0.01 ml/kg) and oxfendasole (10 mg/kg) per os; Group 2 consisted of 15 animals with induced trichocephaliasis, administered no anthelmintics. "
08/12/1966 - "[Therapy of trichuriasis with rectal application of anthelmintics]."
09/01/1981 - "[Clinical and epidemiological efficacy of new anthelmintics in foci of ascariasis and trichuriasis]."
12/01/1980 - "Clinical trials on the three broad spectrum anthelmintics against trichuriasis, ascariasis and hookworm infection were carried out in a rural community in Irosin, Sorsogon. "

04/30/1962 - "[Contribution to the study of trichuriasis in the chimpanzee and of its treatment with methyridine]."
03/01/1968 - "Efficacy of methyridine 2- [2-methoxyethyl] pyridine in the treatment of trichuriasis in camel (Camelus dromedarius)."

03/01/1951 - "[Santokin enemas in the treatment of trichocephaliasis and oxyuriasis; antiparasitic intra-intestinal chemo-colloidal therapy]."
01/01/1952 - "[Treatment of trichocephaliasis with hexylresorcinol (santokin) in a form of enema; report of four cured cases]."
09/01/1951 - "[Nine cases of trichocephaliasis cured with hexylresorcinol enemas (santokin)]."
09/01/1951 - "[One hundred cases of trichocephaliasis cured with hexylresorcinol enemas (santokin)]."
07/01/1951 - "[Treatment of trichocephaliasis with hexylresorcinol (santokin) in the form of enemas; report of four cases cured]."

11/01/2011 - "Though trichuriasis is a significant public health problem, few effective drugs are available underscoring the need for new drug therapies. "
09/01/1958 - "[Chemotherapy of trichuriasis; studies on experimental infection of dogs with Trichuris vulpis]."
05/01/2003 - "Where trichuriasis is a major problem, single dose chemotherapy may take some time to reduce prevalence, but reduction of heavy infections will reduce the incidence of Trichuris Dysentery Syndrome, probably benefit the learning abilities of affected schoolchildren, and may reduce anaemia and stunting. "
05/02/1996 - " Mass chemotherapy with single doses of albendazole or the older drug, mebendazole, is feasible for school-age children to treat the soil-transmitted helminthiases (ascariasis, hook-worm infection, and trichuriasis). "

05/01/1994 - "Serum isotype responses after treatment of human trichuriasis."
02/01/1978 - "The reduction rates as seen by mean egg counts four weeks after treatment were 94.9% for hookworm infection, 100% for ascariasis and 93.9% for trichuriasis; the reduction rates of the mean larval count in 15 cases of strongyloidiasis was 82.1%. "
01/01/2003 - "For trichuriasis, albendazole + ivermectin gave significantly higher cure and egg reduction rates than the other treatments: the infection rates were lower 180 and 360 days after treatment. "

07/01/1959 - "[Experience with combined therapy of trichocephaliasis in children with oxygen and diathermy]."