Trichloroethylene (Trichloroethene)

A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.

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Networked: 775 relevant articles (5 outcomes, 81 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Huang, Hanlin: 19 articles (10/2022 - 11/2004)
2.	Li, Laiyu: 17 articles (10/2022 - 11/2004)
3.	Kamijima, Michihiro: 15 articles (10/2022 - 03/2002)
4.	Wang, Hui: 15 articles (01/2022 - 08/2014)
5.	Gilbert, Kathleen M: 15 articles (08/2018 - 01/2004)
6.	Nakajima, Tamie: 14 articles (10/2022 - 01/2003)
7.	Rothman, Nathaniel: 14 articles (10/2022 - 08/2010)
8.	Blossom, Sarah J: 14 articles (01/2020 - 11/2004)
9.	Shen, Tong: 13 articles (11/2020 - 10/2007)
10.	Zhu, Qixing: 12 articles (05/2022 - 11/2013)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2016 - "Residential cancer cluster investigation nearby a Superfund Study Area with trichloroethylene contamination." 08/01/2001 - "The study is performed by comparing 29 cancer risk assessments made of one and the same chemical substance, namely, trichloroethylene. " 05/01/2000 - "Studies on the metabolism of trichloroethylene in rodents and in humans support the role of bioactivation reactions for the development of tumors following exposure to trichloroethylene. " 06/01/1997 - "Trichloroethylene-induced mouse lung tumors: studies of the mode of action and comparisons between species." 11/01/2022 - "With the exception of high exposure to trichloroethylene, the substances mentioned can also environmentally trigger the same tumors. "
2.	Poisoning 05/01/1982 - "[Value of the study of trigeminal nerve evoked potentials in chronic trichloroethylene poisoning. " 09/01/1971 - "[Biochemical and neurologic studies in acute oral poisoning with trichloroethylene (Tri)]." 01/01/1970 - "Subacute and chronic trichloroethylene poisoning: a neuropathological study in rabbits." 10/01/1966 - "[Clinical observation and neurophysiological study of a case of chronic trichloroethylene poisoning]." 09/01/1962 - "[Contribution to the study of chronic trichloroethylene poisoning]."
3.	Drug Eruptions (Drug Eruption) 03/01/2015 - "To study the expression of C3aR and C5aR in trichloroethylene-sensitized mouse liver injury and discuss the pathogenesis of Dermatitis Medicamentosa-like of TCE (DMLT). " 10/01/2011 - "[Dynamic change study of dermatitis medicamentosa-like of trichloroethylene patients with liver damage]." 11/01/2011 - "[Analysis of subgroups of lymphocyte in peripheral blood among dermatitis medicamentosa-like of trichloroethylene patients and healthy exposed workers]." 10/01/2011 - "The early liver damage in dermatitis medicamentosa-like of trichloroethylene patients was serious, and repeatedly attacked, so we should lead to enough attention to the clinical work and prevention. " 01/01/2012 - "To study the better efficacy of clinic treatment for dermatitis medicamentosa like of trichloroethylene (DMLT) and observe the clinic efficacy of Xuebejing injection for DMLT patients with systemic inflammatory response syndrome (SIRS). "
4.	Inflammation (Inflammations) 01/01/2023 - "Autophagy dysregulation in trichloroethene-mediated inflammation and autoimmune response." 01/01/2018 - "Opposing Actions of Developmental Trichloroethylene and High-Fat Diet Coexposure on Markers of Lipogenesis and Inflammation in Autoimmune-Prone Mice." 01/01/2017 - "We immunized guinea pigs with trichloroethylene using the Guinea Pig Maximization Test (GPMT) and scored the inflammation on the guinea pigs' skin. " 01/01/2020 - "Sex-Dependent Effects on Liver Inflammation and Gut Microbial Dysbiosis After Continuous Developmental Exposure to Trichloroethylene in Autoimmune-Prone Mice." 01/01/2020 - "Enhancing the Nrf2 Antioxidant Signaling Provides Protection Against Trichloroethene-mediated Inflammation and Autoimmune Response."
5.	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/01/2012 - "To study the better efficacy of clinic treatment for dermatitis medicamentosa like of trichloroethylene (DMLT) and observe the clinic efficacy of Xuebejing injection for DMLT patients with systemic inflammatory response syndrome (SIRS). " 01/01/2012 - "[Research of xuebijing injection combined with glucocorticoid in treating dermatitis medicamentosa like of trichloroethylene with systemic inflammatory response syndrome]."

Related Drugs and Biologics

1.	Benzene (Benzole)
2.	Carcinogens
3.	Methylene Chloride (Dichloromethane)
4.	Carbon Tetrachloride (Tetrachloromethane)
5.	Asbestos
6.	Glucose (Dextrose)
7.	Arsenic
8.	Formaldehyde (Formol)
9.	1,3-butadiene (divinyl)
10.	Antioxidants

Related Therapies and Procedures

1.	Anesthesia
2.	Analgesia
3.	Therapeutics
4.	Resuscitation
5.	Oral Administration