Trichloroethylene (Trichloroethene)

A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.

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Networked: 579 relevant articles (4 outcomes, 57 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Huang, Hanlin: 14 articles (01/2015 - 11/2004)
2.	Li, Laiyu: 12 articles (01/2015 - 11/2004)
3.	Gilbert, Kathleen M: 11 articles (09/2014 - 01/2004)
4.	Kamijima, Michihiro: 11 articles (12/2013 - 03/2002)
5.	Niu, Yong: 10 articles (01/2015 - 11/2004)
6.	Nakajima, Tamie: 10 articles (12/2013 - 01/2003)
7.	Blossom, Sarah J: 9 articles (09/2014 - 11/2004)
8.	Rothman, Nathaniel: 8 articles (01/2015 - 08/2010)
9.	Shen, Tong: 6 articles (09/2015 - 10/2007)
10.	Zheng, Yuxin: 6 articles (01/2015 - 11/2004)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2001 - "The study is performed by comparing 29 cancer risk assessments made of one and the same chemical substance, namely, trichloroethylene. " 03/05/2001 - "Trichloroethylene and cancer: a carcinogen on trial." 05/01/2000 - "Studies on the metabolism of trichloroethylene in rodents and in humans support the role of bioactivation reactions for the development of tumors following exposure to trichloroethylene. " 05/01/2000 - "Although we believe that solvent exposure causes cancer in humans and that trichloroethylene likely is one of the active agents, we recommend further study to better specify the specific agents that confer this risk and to estimate the magnitude of that risk." 06/01/1997 - "Trichloroethylene-induced mouse lung tumors: studies of the mode of action and comparisons between species."
2.	Poisoning 05/01/1982 - "[Value of the study of trigeminal nerve evoked potentials in chronic trichloroethylene poisoning. " 09/01/1971 - "[Biochemical and neurologic studies in acute oral poisoning with trichloroethylene (Tri)]." 01/01/1970 - "Subacute and chronic trichloroethylene poisoning: a neuropathological study in rabbits." 10/01/1966 - "[Clinical observation and neurophysiological study of a case of chronic trichloroethylene poisoning]." 09/01/1962 - "[Contribution to the study of chronic trichloroethylene poisoning]."
3.	Drug Eruptions (Drug Eruption) 03/01/2015 - "To study the expression of C3aR and C5aR in trichloroethylene-sensitized mouse liver injury and discuss the pathogenesis of Dermatitis Medicamentosa-like of TCE (DMLT). " 10/01/2011 - "[Dynamic change study of dermatitis medicamentosa-like of trichloroethylene patients with liver damage]." 11/01/2011 - "[Analysis of subgroups of lymphocyte in peripheral blood among dermatitis medicamentosa-like of trichloroethylene patients and healthy exposed workers]." 10/01/2011 - "The early liver damage in dermatitis medicamentosa-like of trichloroethylene patients was serious, and repeatedly attacked, so we should lead to enough attention to the clinical work and prevention. " 01/01/2012 - "To study the better efficacy of clinic treatment for dermatitis medicamentosa like of trichloroethylene (DMLT) and observe the clinic efficacy of Xuebejing injection for DMLT patients with systemic inflammatory response syndrome (SIRS). "
4.	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/01/2012 - "To study the better efficacy of clinic treatment for dermatitis medicamentosa like of trichloroethylene (DMLT) and observe the clinic efficacy of Xuebejing injection for DMLT patients with systemic inflammatory response syndrome (SIRS). " 01/01/2012 - "[Research of xuebijing injection combined with glucocorticoid in treating dermatitis medicamentosa like of trichloroethylene with systemic inflammatory response syndrome]."
5.	Hyperglycemia 03/01/1989 - "3. Intravenous glucose tolerance tests (0.5 g/kg load) revealed that decreasing constant of plasma glucose (K value) was elevated by trichloroethylene, suggesting that induced hyperglycemia in the exposed rats improved more rapidly than in the controls. " 03/01/1989 - "The foregoing results indicate that trichloroethylene-induced glycosuria is attributable to deteriorated tubular reabsorption of glucose, and not to hyperglycemia. "

Related Drugs and Biologics

1.	Benzene (Benzole)
2.	Carcinogens
3.	Glucose (Dextrose)
4.	Methylene Chloride (Dichloromethane)
5.	Carbon Tetrachloride (Tetrachloromethane)
6.	Asbestos
7.	Formaldehyde (Formol)
8.	Arsenic
9.	Acetylcysteine (Siran)
10.	1,3-butadiene

Related Therapies and Procedures

1.	Anesthesia
2.	Analgesia
3.	Resuscitation
4.	Oral Administration
5.	Synchrotrons