HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Triamterene (Dyrenium)

Subscribe to New Research on Triamterene

A pteridine that is used as a mild diuretic.

Also Known As:

Dyrenium; Dytac; Goldshield Brand of Triamterene; Jorba Brand of Triamterene; SmithKline Beecham Brand of Triamterene; Urocaudal; Wellspring Brand of Triamterene; 2,4,7-Pteridinetriamine, 6-phenyl-

Networked: 241 relevant articles (12 outcomes, 26 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Jiang, Yajian: 1 article (12/2015)
2.	Lu, Lingping: 1 article (12/2015)
3.	Ke, Qing: 1 article (12/2015)
4.	Qi, Ming: 1 article (12/2015)
5.	He, Fangping: 1 article (12/2015)
6.	Weng, Chen: 1 article (12/2015)
7.	Yu, Ping: 1 article (12/2015)
8.	Huang, Hui: 1 article (12/2015)
9.	Yi, Xin: 1 article (12/2015)
10.	Sica, Domenic A: 1 article (04/2015)

Related Diseases

1.	Hypertension (High Blood Pressure) 02/01/1997 - "The triamterene therapy was effective in correcting the endocrine and metabolic disorders as well as arterial hypertension, but did not prevent a deficit in mental and physical development. " 01/01/1994 - "Triamterene, a diuretic drug used in combination with other drugs for the treatment of hypertension, was found in the blood and urine of a fatal aircraft accident victim. " 11/01/1979 - "Triamterene was administered in a dose of 100 mg/day for 8 days to 7 patients with essential hypertension. " 11/01/1979 - "Effect of triamterene on urinary excretion of immunoreactive prostaglandin E in essential hypertension." 12/01/1972 - "The effect of triamterene on plasma and extracellular fluid volume and blood pressure in ten thiazide-treated hypokalemic patients with essential hypertension."
2.	Heart Failure 11/01/1969 - "[Administration of triamterene in congestive heart failure]." 08/15/1964 - "Triamterene therapy was evaluated in 35 patients with congestive heart failure over a period of two and one-half years. " 08/15/1964 - "CLINICAL EXPERIENCE WITH A NEW DIURETIC, TRIAMTERENE, IN CONJESTIVE HEART FAILURE." 01/01/1985 - "Piretanide (6 mg once daily) and piretanide plus triamterene (6 mg + 50 mg once daily) both produced a significant reduction in certain symptoms of congestive heart failure which was evident at 2 weeks and was maintained and further enhanced over the ensuing 12-week trial period. " 01/01/1985 - "Improvement in a number of symptoms of congestive heart failure was attained in 54% of the patients in the piretanide group and 67% in the piretanide plus triamterene group. "
3.	Fibrosis (Cirrhosis) 06/01/1984 - "There was 92% reduction in apparent oral clearance of triamterene (134 +/- 42 ml/min) in patients with cirrhosis. " 05/01/1968 - "[Clinical and biochemical study of the therapeutic effect of the diuretic triamterene in ascitogenic cirrhosis]." 02/01/1988 - "Kinetics and dynamics of triamterene at steady-state in patients with cirrhosis." 06/01/1984 - "These changes in triamterene kinetics in patients with cirrhosis resulted in prolongation of its natriuretic effect, which lasted for up to 48 hr, whereas it was only 8 hr in the controls. " 06/01/1984 - "Triamterene kinetics and dynamics in cirrhosis."
4.	Hypokalemia 10/01/2014 - "Hypokalemia risk is influenced by age and dosage, and is still increased if used in combination with triamterene." 06/01/1995 - "Once the diagnosis of Liddle's syndrome was suspected, all patients were treated with either triamterene or ameloride, with resolution of hypokalemia and correction of hypertension occurring within 5 to 7 days. " 11/01/1985 - "Potassium chloride was compared with triamterene in a crossover trial involving 16 hypertensive patients with overt diuretic-induced hypokalemia. " 03/01/1989 - "A combination of hydrochlorothiazide and triamterene had been previously prescribed despite no history of hypokalemia. " 09/01/1987 - "Results indicate that K salt supplementation did not reverse the gossypol-related hypokalemia and that the blocking agent triamterene did not prevent loss of or enhance the retention of serum K. "
5.	Calculi (Calculus) 01/01/1982 - "An estimated 150 to 200 calculi with triamterene are probably eliminated though not detected every year in France. " 03/01/1987 - "Triamterene calculus]." 02/01/1986 - "The saturation of urine with triamterene and especially with the sulfate ester, 3, may be related to stone formation, but other physical factors play a role in determining the relative amounts of drug found in calculus material." 06/01/1985 - "Triamterene calculus." 01/01/1982 - "The composition of drug layers is almost the same in the 4 calculi and shows a mixture of triamterene (estimated at 35% of iatrogenic components) and 7 metabolites among them p-hydroxy-triamterene (5-10%) and mainly p-hydroxytriamterene estersulfate (40-55%). "

Related Drugs and Biologics

1.	Potassium
2.	Chlorthalidone (Chlortalidone)
3.	piretanide
4.	Potassium Chloride
5.	Spironolactone (Aldactone)
6.	Amiloride (Midamor)
7.	Magnesium
8.	Dihydrotachysterol (AT 10)
9.	Leucovorin (Folinic Acid)
10.	Hydrochlorothiazide (Esidrix)

Related Therapies and Procedures

1.	Sodium-Restricted Diet (Diet, Sodium Restricted)
2.	Oral Administration
3.	Endoscopes
4.	Protein-Restricted Diet (Diet, Protein Restricted)
5.	Injections