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Transferrin (beta 2 Transferrin)

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Serum beta-globulin that binds and transports iron. (From Dorland, 28th ed)

Also Known As:

beta 2 Transferrin; In-Transferrin; Isotransferrin; Monoferric Transferrins; Serotransferrin; Tf C; Transferrin B; Transferrin C; beta 2-Transferrin; tau-Transferrin; 2-Transferrin, beta; B, Transferrin; C, Tf; C, Transferrin; In Transferrin; Transferrins, Monoferric; tau Transferrin; Siderophilin; Transferrins

Networked: 3829 relevant articles (115 outcomes, 369 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489

Experts

1.	Adams, Paul C: 23 articles (10/2014 - 07/2002)
2.	McLaren, Gordon D: 17 articles (02/2014 - 01/2005)
3.	McLaren, Christine E: 15 articles (02/2014 - 01/2005)
4.	Barton, James C: 15 articles (07/2013 - 01/2005)
5.	Acton, Ronald T: 13 articles (12/2008 - 01/2005)
6.	Barton, J C: 13 articles (08/2008 - 01/2000)
7.	Camaschella, Clara: 12 articles (04/2015 - 10/2002)
8.	Brissot, Pierre: 12 articles (02/2015 - 01/2002)
9.	Gordeuk, Victor R: 12 articles (01/2009 - 08/2003)
10.	Olynyk, John K: 11 articles (04/2015 - 03/2002)

Related Diseases

1.	Neoplasms (Cancer) 04/28/2014 - "Targeted therapy for the treatment of cancers using nanoparticles (NPs) decorated with transferrin (Tf) has been relatively successful, as several such nanocarriers are currently undergoing clinical trials. " 01/01/2012 - "Risk of cancer by transferrin saturation levels and haemochromatosis genotype: population-based study and meta-analysis." 10/01/2011 - "The present study reports a detailed investigation into the interaction of [Cr(phen)(2)(dppz)](3+) and [Cr(phen)(3)](3+) with transferrin, the key protein for the transport of Fe(3+) in blood plasma; its cycle holds promise as an attractive system for strategies of drug targeting to tumor tissues. " 10/01/2011 - "Our studies indicate that transferrin plays an important role in the transport and targeted delivery of Cp(2)VCl(2) into cancer cells." 10/01/2011 - "In this study, whether transferrin could transport noncovalent binding drugs into cancer cells has been investigated. "
2.	Body Weight (Weight, Body) 11/01/2013 - "Human milk was less effective than cow milk to increase body weight and serum transferrin levels. " 04/01/2007 - "The measurement of body weight and estimation of transferrin levels can be useful for the nutritional assessment during allogeneic HSCT from sibling donors. " 01/01/2005 - "There was no difference between In-transferrin accumulation rates in these rats when a stringent selection was made based on end-inspiratory pressure (28-32 cm H(2)O) or body weight (330-360 g). " 07/01/2001 - "Body weights, serum levels of total protein and transferrin, and enterocyte proliferation were significantly lower after SBR including ICV than preserving it. " 07/01/2000 - "The group as a whole had low mean values for body weight, albumin and transferrin and high CRP levels. "
3.	Anemia 01/01/2016 - "We show that STEAP3, a metalloreductase expressed in erythroblasts, associates with TfR1 and partially rescues transferrin uptake in patient-derived fibroblasts, suggesting that STEAP3 may provide an accessory TfR1 endocytosis signal that spares patients from severe anemia. " 12/01/2006 - "Transferrin serum levels were significantly diminished in the third blood sampling, indicating the tendency toward anemia in the patients. " 09/01/2006 - "A low transferrin saturation ratio was observed in 68% of the obese patients; moreover, 24% of these patients presented with anemia. " 09/01/2006 - "Female sex, African American race, reduced kidney function, reduced transferrin saturation, and diabetes as the cause of CKD were strongly associated with anemia. " 05/01/2006 - "The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling."
4.	Carcinoma (Carcinomatosis) 04/01/2014 - "Therapeutic efficacy of intravenously administered transferrin-conjugated dendriplexes on prostate carcinomas." 01/01/2012 - "We also summarize the studies on the use of transferrin-lipoplexes for enhancing gene delivery to cervical carcinoma, murine colon carcinoma, and African green monkey kidney cells. " 09/14/2006 - "Excess transferrin (200 microg per well) reduced transfection levels to those of untargeted complexes, supporting the notion that at least 50% of ternary complexes gained entry into the cervical carcinoma cells by receptor mediation. " 07/05/1997 - "In previous works, other authors characterized a compartment (LCT) of A431 carcinoma cells in which markers of transferrin endocytose had accumulated during a long chase period. " 01/01/1997 - "Autocrine growth induced by transferrin-like substance in bladder carcinoma cells."
5.	Proteinuria 01/01/1989 - "Also, in the present study, a rapid biochemical method of measurement of the selectivity of proteinuria based on the transferrin/albumin ratios in random samples is reported. " 04/01/2003 - "Urinary transferrin, high molecular weight proteinuria and the progression of renal disease." 04/01/1997 - "Urine/serum (U/S) ratio of %G-albumin in the patients with diabetic proteinuria was significantly lower than that in subjects with non-diabetic proteinuria, while no difference of the U/S ratio of %G-transferrin was observed between any groups. " 05/01/1972 - "Transferrin excretion in patients with proteinuria." 04/01/2003 - "Rate of change of renal function correlated with total proteinuria (r2 = 18%, p < 0.001) and albuminuria (r2 = 17%, p < 0.001), but not urinary transferrin (r2 = 0%, p = 0.235). "

Related Drugs and Biologics

1.	Iron
2.	Ferritins (Ferritin)
3.	Liposomes (Liposome)
4.	Prealbumin (Transthyretin)
5.	Transferrin Receptors (Transferrin Receptor)
6.	Serum Albumin
7.	Immunoglobulin G (IgG)
8.	Doxorubicin (Adriamycin)
9.	Hemoglobins (Hemoglobin)
10.	Haptoglobins

Related Therapies and Procedures

1.	Nutritional Support (Artificial Feeding)
2.	Drug Therapy (Chemotherapy)
3.	Renal Dialysis (Hemodialysis)
4.	Heterologous Transplantation (Xenotransplantation)
5.	Intravenous Infusions