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Tracheobronchomegaly (Mounier Kuhn Syndrome)

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A rare and probably congenital condition characterized by great enlargement of the lumen of the trachea and the larger bronchi.

Also Known As:

Mounier Kuhn Syndrome; Congenital Tracheobronchomegaly; Congenital Tracheobronchomegalies; Tracheobronchomegalies; Tracheobronchomegalies, Congenital; Tracheobronchomegaly, Congenital; Mounier-Kuhn Syndrome

Networked: 26 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Tracheobronchomegaly (Mounier Kuhn Syndrome)
2.	Tracheomalacia
3.	Chronic Obstructive Pulmonary Disease (COPD)
4.	Tracheobronchomalacia
5.	Interstitial Lung Diseases (Interstitial Lung Disease)

Experts

1.	Pettersson, Gosta: 2 articles (09/2006 - 03/2006)
2.	Mehta, Atul C: 2 articles (09/2006 - 03/2006)
3.	Klepetko, Walter: 1 article (07/2015)
4.	Mildner, Michael: 1 article (07/2015)
5.	Birner, Peter: 1 article (07/2015)
6.	Hoetzenecker, Konrad: 1 article (07/2015)
7.	Prosch, Helmut: 1 article (07/2015)
8.	Mitterbauer, Andreas: 1 article (07/2015)
9.	Taghavi, Shahrokh: 1 article (07/2015)
10.	Streubel, Berthold: 1 article (07/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tracheobronchomegaly:

1.	General AnestheticsIBA 06/01/2013 - "Management of a patient with Mounier-Kuhn syndrome undergoing repeated general anesthetics."
2.	YttriumIBA 06/01/2011 - "We report a case of Mounier-Kuhn syndrome that was successfully managed by treating the posterior collapse of the central airway with yttrium aluminum pevroskyte laser. "
3.	OxygenIBA 04/01/1987 - "We present five cases of tracheobronchomegaly occurring in neonates receiving intensive ventilatory and oxygen support. "
4.	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 08/01/1982 - "A postulated mechanism for these alterations in pulmonary connective tissue productive of malformations which model human tracheobronchomegaly and cystic lungs, is interference with lysyl oxidase, a copper-requiring enzyme, which cross-links elastin."
5.	ElastinIBA 08/01/1982 - "A postulated mechanism for these alterations in pulmonary connective tissue productive of malformations which model human tracheobronchomegaly and cystic lungs, is interference with lysyl oxidase, a copper-requiring enzyme, which cross-links elastin."
6.	CopperIBA 08/01/1982 - "A postulated mechanism for these alterations in pulmonary connective tissue productive of malformations which model human tracheobronchomegaly and cystic lungs, is interference with lysyl oxidase, a copper-requiring enzyme, which cross-links elastin."
7.	AluminumIBA 06/01/2011 - "We report a case of Mounier-Kuhn syndrome that was successfully managed by treating the posterior collapse of the central airway with yttrium aluminum pevroskyte laser. "
8.	Congenital diaphragmatic herniaIBA 08/01/2012 - "Tracheobronchomegaly following intrauterine tracheal occlusion for congenital diaphragmatic hernia."
9.	Kenny Caffey syndromeIBA 08/01/1992 - "A 36-year-old woman with features of both the Mounier-Kuhn syndrome and the Kenny-Caffey syndrome is described. " 08/01/1992 - "The Mounier-Kuhn syndrome in a patient with the Kenny-Caffey syndrome."
10.	A 19IBA 08/01/1990 - "[Tracheobronchomegaly in a 19 month old infant]."

Therapies and Procedures

1.	Prostheses and Implants (Prosthesis) 02/01/2002 - "We report the case of one patient with tracheobronchomegaly who was greatly improved after implantation of Ultraflex tracheobronchial prostheses." 05/01/2015 - "[Tracheobronchial prosthesis in Mounier-Kuhn syndrome: New perspectives]." 02/01/2002 - "[Treatment of tracheobronchomegaly with an Ultraflex prosthesis. " 06/01/1998 - "[Treatment of tracheobronchomegaly using the Freitag prosthesis]."
2.	Lung Transplantation 01/01/2015 - "Anesthetic considerations for bilateral lung transplantation in Mounier-Kuhn syndrome." 10/01/2013 - "Long-term success after bilateral lung transplantation for Mounier-Kuhn syndrome: a physiological description." 09/01/2006 - "Lung transplantation in a patient with Mounier-Kuhn syndrome." 01/01/2006 - "We report a case in which a patient underwent successful double lung transplantation for COPD that was found on pathologic examination of the explanted lungs to be Mounier Kuhn syndrome. " 01/01/2006 - "Double lung transplantation in a patient with tracheobronchomegaly (Mounier-Kuhn syndrome)."
3.	Stents 01/01/2014 - "Tracheomalacia treatment using a large-diameter, custom-made airway stent in a case with mounier-kuhn syndrome." 09/01/2004 - "Tracheomalacia associated with Mounier-Kuhn syndrome in the Intensive Care Unit: treatment with Freitag stent. " 10/01/1995 - "[Tracheobronchomegaly (Mounier-Kuhn syndrome): roentgen findings and tracheal stent instrumentation]."
4.	Transplantation (Transplant Recipients) 03/01/2006 - "Pulmonary transplantation in Mounier-Kuhn syndrome: a case report." 07/01/2015 - "Clinical-radiological, histological and genetic analyses in a lung transplant recipient with Mounier-Kuhn syndrome and end-stage chronic obstructive pulmonary disease."
5.	Artificial Respiration (Mechanical Ventilation) 01/01/1995 - "Tracheobronchomegaly (TBM) was diagnosed on chest radiographs as an apparent dilatation of the trachea and main bronchi in four premature infants on prolonged mechanical ventilation for respiratory distress syndrome. " 01/01/1995 - "Tracheobronchomegaly in preterm infants on mechanical ventilation." 03/01/1989 - "It may be preferable in patients with Mounier-Kuhn syndrome who require mechanical ventilation to intubate the trachea with an uncuffed tube and to pack the throat to decrease the chances of gas leak and inhalation."