Tourniquets

Devices for the compression of a blood vessel by application around an extremity to control the circulation and prevent the flow of blood to or from the distal area. (From Dorland, 28th ed)

Also Known As:

Networked: 3616 relevant articles (199 outcomes, 446 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Kragh, John F: 52 articles (01/2020 - 04/2007)
2.	Dubick, Michael A: 46 articles (01/2021 - 06/2006)
3.	Walters, Thomas J: 29 articles (01/2022 - 09/2005)
4.	Aden, James K: 29 articles (01/2020 - 12/2012)
5.	Holcomb, John B: 23 articles (02/2022 - 10/2005)
6.	Baer, David G: 20 articles (01/2016 - 10/2005)
7.	Schauer, Steven G: 16 articles (01/2022 - 08/2017)
8.	April, Michael D: 13 articles (01/2022 - 08/2017)
9.	Kauvar, David S: 13 articles (01/2021 - 10/2005)
10.	Butler, Frank K: 12 articles (02/2022 - 06/2007)

Related Diseases

1.	Hemorrhage 11/01/2017 - "Recent data from the ongoing conflicts in Iraq and Afghanistan suggest that early and aggressive tourniquet utilization is a safe and effective way to dramatically reduce mortality from extremity hemorrhage. " 01/01/2009 - "From the results, it is concluded that the Emergency Bandage pressure bar is very effective in elevating the applied pressure directly under the pressure bar while at the same time not applying unnecessary pressure over other areas covered by the bandage, which allows control of hemorrhage at the site of injury (under the pressure bar area) without having to have a full tourniquet effect. " 12/01/2021 - "Despite lower mortality with use of tourniquets and WB, mortality rates due to hemorrhage have not improved at our high MTP volume institution, suggesting implementation of new in-hospital strategies is insufficient to reduce mortality. " 08/28/2020 - "The intraoperative bleeding in the treatment group was significantly lower than that of the control group (17.56 ± 3.52 ml vs 49.87 ± 8.78 ml, P < .01).High ligation, great saphenous vein stripping, and subfascial perforator vein surgery under the assistance of sterilized electric pneumatic tourniquet and Esmarch's bandage was effective for the treatment of varicosis in lower limbs featured by reduced surgery time and less bleeding." 01/01/2014 - "The Abdominal Aortic and Junctional Tourniquet(tm) is (1) a Food and Drug Administration?cleared device that is currently indicated for pelvic, inguinal, and axillary bleeding; (2) the only junctional tourniquet with an indication for pelvic bleeding; (3) the only junctional tourniquet reported with a successful axillary use; and (4) effective at lower tissue pressures than other junctional tourniquets available."
2.	Pain (Aches) 02/21/2022 - "Thigh pain VAS score at 1 month after surgery was significantly greater in the tourniquet group (P < 0.001), as was knee pain during activity and at rest on PODs 2-3 (all P < 0.05). " 10/01/2018 - "Patients who underwent carpal tunnel decompression using a tourniquet experienced a significantly greater degree of pain when compared with those who did not have a tourniquet. " 11/01/1997 - "Therapy was considered successful if significant reduction of pain and tenderness was noted after tourniquet release. " 12/01/1990 - "There was significant pain relief in all three groups at 30 min. There were no significant differences among the three groups in the degree of pain relief, the number of patients obtaining pain relief in the 30 min after the block, or the number of patients reporting more than 50% pain relief for more than 24 hr. The saline group's high rate of pain relief could be partially due to a mechanism of tourniquet-induced analgesia." 04/01/2019 - "When the results in this study for surgery performed with and without tourniquet are compared, no clear benefit for either procedure was observed, as the more pain exhibited by the nontourniquet group was only evident for a short period and the improved mobility in this group was not at a clinically relevant level. "
3.	Wounds and Injuries (Trauma) 01/01/2018 - "Traumatic injuries to the pelvis and high junctional injuries are difficult to treat in the field; however, Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) and the Abdominal Aortic and Junctional Tourniquet (AAJT) constitute two promising treatment modalities. " 01/01/2017 - "Monitoring structural and functional repair of the NMJ, nerve, and skeletal muscle after tourniquet-induced injuries is beneficial in exploring potential cellular and molecular mechanisms responsible for tourniquet-induced injuries, and for establishing effective therapeutic interventions. " 04/01/2017 - "Therefore, we performed current meta-analysis to assess whether releasing tourniquet before wound closure is more effective in reducing blood loss than releasing tourniquet after wound closure in TKA without an increased risk of complications. " 12/03/2014 - "The current evidences are not enough to indicate that tourniquet release before wound closure is superior to its release after wound closure in cemented TKA." 07/01/2023 - "Prehospital tourniquets (PHTQ) for trauma have been shown to be safe and effective in the military environment and in some civilian settings. "
4.	Ischemia 07/01/2021 - "Considering the optimal results in terms of erectile functions increasing and absence of PC recurrence (>15°), we think that Nesbit modified corporoplasty without tourniquet application during reconstruction is a safe and effective surgical procedure for all kind of shortening corporoplasty to reduce the time of penile ischemia, preventing even serious consequences for the normal physiology of erection." 09/01/1994 - "Tourniquet-induced ischemia resulted in (a) a marked decrease of functional capillary density and (b) accumulation and adherence of leukocytes in postcapillary venules after 30 min and 2 h of reperfusion. " 01/01/1998 - "The substantial gain in strength and maximal rate of torque development in I-leg demonstrated the efficacy of tourniquet ischemia during low-resistance training of short duration, and suggested the importance of neuromuscular and/or metabolic activity, other than high mechanical stress, to the adapting responses to strength training." 08/01/1990 - "Rapid infusions of isotonic saline solutions over the last five minutes of tourniquet ischemia, aiming at increasing the circulating blood volume of the animals at start of the ischemic leg reperfusion by 2.0, 4.5, and 9.5 ml respectively, or by approximately 10%, 25% and 50%, gave no significant improvement in post-ischemic reperfusion, except in that following 3 hours of leg ischemia and after the two largest volumes. " 01/01/2023 - "Ischemic preconditioning (IPC), a procedure that involves the cyclic induction of limb ischemia and reperfusion via tourniquet inflation, has been reported to improve exercise capacity and performance, but the underlying mechanisms remain unclear. "
5.	Reperfusion Injury 03/01/2015 - "HES infusion may be beneficial for reduction of tourniquet-associated ischemia-reperfusion injury; however, further large-scale studies are needed to fully elucidate its mechanism." 11/01/2016 - "Ischemia-reperfusion injury decreased viability in all tourniquet limbs, but viability was not improved in either PostC group. " 01/01/2023 - "This study was designed to investigate the ability of VPA to mitigate ischemia-reperfusion injury produced by prolonged tourniquet application to an extremity. " 01/01/2015 - "In this study we used bone-marrow derived in vitro LPS/IFN-y-induced M1 MPs to enhance functional muscle recovery after tourniquet-induced ischemia/reperfusion injury (TK-I/R). " 01/01/2008 - "The aim of this study was to investigate the systemic and local inflammatory response after tourniquet-induced skeletal muscle ischaemia-reperfusion injury in patients undergoing total knee replacement. "

Related Drugs and Biologics

1.	Lidocaine (Xylocaine)
2.	Propofol (Diprivan)
3.	Ketamine
4.	Hemostatics (Antihemorrhagics)
5.	Bupivacaine (Bupivacaine Hydrochloride)
6.	Analgesics (Analgesic Drugs)
7.	Dexmedetomidine
8.	Morphine (MS Contin)
9.	Fentanyl (Sublimaze)
10.	Meperidine (Pethidine)

Related Therapies and Procedures

1.	Analgesia
2.	Knee Replacement Arthroplasty (Total Knee Replacement)
3.	Conduction Anesthesia (Regional Anesthesia)
4.	Anesthesia
5.	Tourniquets