Tooth Discoloration

Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)

Also Known As:

Networked: 93 relevant articles (3 outcomes, 12 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Inflammation
2.	Malnutrition
3.	Acne Vulgaris
4.	Hypersensitivity (Allergy)
5.	Dental Enamel Hypoplasia

Experts

1.	Addy, M: 4 articles (05/2015 - 01/2004)
2.	Van der Weijden, G A: 2 articles (05/2015 - 02/2014)
3.	Jung, Il-Young: 2 articles (05/2015 - 06/2010)
4.	Slot, D E: 2 articles (05/2015 - 02/2014)
5.	Azodo, C C: 2 articles (09/2014 - 12/2012)
6.	Parashos, Peter: 2 articles (04/2013 - 07/2011)
7.	Ishikawa, Kunio: 2 articles (10/2012 - 01/2010)
8.	Suge, Toshiyuki: 2 articles (10/2012 - 01/2010)
9.	Matsuo, Takashi: 2 articles (10/2012 - 01/2010)
10.	Chu, Frederick C S: 2 articles (04/2009 - 11/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tooth Discoloration:

1.	Tetracycline (Achromycin)FDA LinkGeneric 09/01/2006 - "This study tested the hypothesis that exposure of human molar teeth to tetracycline (TCN) derivatives in vitro results in tooth discoloration resembling the clinical presentation of TCN staining. " 08/01/1989 - "Tooth discoloration due to tetracycline, 3 subjects in this study, has previously been regarded as difficult to bleach, could be carried out satisfactorily with few appointments. " 08/01/1992 - "Tooth discoloration resulting from long-term tetracycline therapy: a case report." 01/01/1991 - "[Modern views on treating tooth discoloration from tetracycline]." 11/01/1989 - "[Influence of the treatment of tooth discoloration caused by tetracycline on the structure of teeth]."
2.	ChlorhexidineIBA 01/01/2004 - "The interaction of chlorhexidine with dietary chromogens to cause extrinsic dental staining has been exploited in vitro and in vivo to study tooth discoloration and its control. " 05/01/2015 - "Chlorhexidine mouthwash, however, showed a significantly more tooth discoloration than the CHX DF/gel. " 11/23/1985 - "Extrinsic tooth discoloration by metals and chlorhexidine. " 11/09/1985 - "Extrinsic tooth discoloration by metals and chlorhexidine. " 05/01/1985 - "Stainers and non-stainers were selected on the basis of their individual tendency to develop extrinsic tooth discolorations from a chlorhexidine mouth rinse. "
3.	TetracyclinesIBA 11/01/2003 - "Tetracyclines cause fetal tooth discoloration and inhibition of bone growth if used in the second and third trimesters. " 06/01/1974 - "Tooth discoloration from tetracyclines." 08/01/1972 - "The tetracyclines and tooth discoloration." 05/06/1972 - "Tooth discoloration and tetracyclines." 06/01/2004 - "The common intrinsic tooth discolorations seen in the study are those usually associated with childhood malnutrition, preventable childhood diseases and the irrational use of drugs (tetracyclines). "
4.	Dentifrices (Dentifrice)IBA 09/01/1988 - "The capacity of a new dentifrice to prevent and remove extrinsic tooth discoloration. " 02/01/2014 - "The efficacy of chlorhexidine dentifrice or gel on plaque, clinical parameters of gingival inflammation and tooth discoloration: a systematic review." 05/01/2015 - "To systematically review and evaluate the available scientific evidence on the effectiveness of chlorhexidine dentifrice or gel (CHX DF/gel) compared to chlorhexidine mouthwash (CHX MW) on plaque, bleeding, gingival inflammation and tooth discoloration scores. " 05/01/2015 - "The effect of chlorhexidine dentifrice or gel versus chlorhexidine mouthwash on plaque, gingivitis, bleeding and tooth discoloration: a systematic review."
5.	Metronidazole (Metric)FDA LinkGeneric 10/01/1997 - "Triple therapy with bismuth, tetracycline, and metronidazole is considered the gold standard for adult patients; however, tetracyclines are not recommended in children younger than 8 years due to the potential for tooth discoloration and alterations in bone growth. "
6.	BismuthIBA 10/01/1997 - "Triple therapy with bismuth, tetracycline, and metronidazole is considered the gold standard for adult patients; however, tetracyclines are not recommended in children younger than 8 years due to the potential for tooth discoloration and alterations in bone growth. "
7.	pemetrexed (MTA)FDA Link 12/01/2013 - "Removing the discolored MTA materials contributed more to resolving the tooth discoloration than post-treatment internal bleaching." 01/01/2012 - "Application of DBA before MTA may prevent tooth discoloration." 07/01/2011 - "This case report describes the treatment of tooth discoloration caused by white MTA (WMTA) used for the management of a complicated crown fracture. " 05/01/2015 - "Furthermore, none of the teeth treated with PCL-FM/MTA direct pulp capping showed tooth discoloration after treatment for 3 months. " 12/01/2013 - "The aim of this study was to evaluate tooth discoloration after the use of mineral trioxide aggregate (MTA) and to examine the effect of internal bleaching on discoloration associated with MTA. "
8.	calcium silicate (Wollastonite)IBA 01/01/2016 - "Evaluation and Comparison of Occurrence of Tooth Discoloration after the Application of Various Calcium Silicate-based Cements: An Ex Vivo Study." 04/01/2015 - "The aim of this study was to evaluate tooth discoloration induced by contact with various calcium silicate-based pulp capping materials in the presence or absence of blood in vitro. " 04/01/2015 - "Tooth discoloration induced by calcium-silicate-based pulp-capping materials." 01/01/2016 - "The purpose of this study was to compare tooth discoloration after the application of ProRoot MTA (Dentsply Tulsa Dental Products, Tulsa, OK) and 3 recently introduced calcium silicate-based cements in the presence and absence of blood. "
9.	mineral trioxide aggregateIBA 12/01/2013 - "Tooth discoloration after the use of new pozzolan cement (Endocem) and mineral trioxide aggregate and the effects of internal bleaching." 04/01/2013 - "Coronal tooth discoloration and white mineral trioxide aggregate." 01/01/2012 - "Effect of dentin bonding agent on the prevention of tooth discoloration produced by mineral trioxide aggregate." 07/01/2011 - "Treatment of tooth discoloration after the use of white mineral trioxide aggregate." 12/01/2013 - "The aim of this study was to evaluate tooth discoloration after the use of mineral trioxide aggregate (MTA) and to examine the effect of internal bleaching on discoloration associated with MTA. "
10.	Minocycline (Cyclops)FDA LinkGeneric 11/01/2015 - "However, tooth discoloration was reported with the use of conventional minocycline-containing TAP. " 06/01/2010 - "Among the components of the triple antibiotic paste, only minocycline caused the tooth discoloration. " 09/01/1998 - "This case is unusual in that the tooth discoloration disappeared after discontinuing minocycline therapy. " 11/22/1985 - "Four of 72 patients who had minocycline therapy during adolescence were found to have minocycline-associated tooth discoloration, which occurred in one case after only four weeks of treatment. " 11/22/1985 - "Minocycline-associated tooth discoloration in young adults."

Therapies and Procedures

1.	Tooth Bleaching 09/01/2013 - "Tooth whitening is considered the easiest and most cost-effective procedure for treating tooth discoloration. " 12/01/2012 - "In the studied population, knowledge of tooth discoloration was high, awareness and experiences of tooth bleaching were low but significant number expressed intention of having tooth bleaching. " 01/01/2009 - "Tooth discoloration is commonly found in the dental clinic and tooth bleaching has been considered the preferred esthetic alternative, being more conservative, safe and with predictable results. " 05/01/2006 - "Compounding pharmacists should increase their knowledge of the types and origins of tooth discoloration, bleaching techniques, and the advantages and disadvantages of tooth bleaching so that they can better serve their patients and be involved in this growing market. " 05/01/2006 - "There are various causes for tooth discoloration and various formulas that can be compounded for tooth bleaching. "
2.	Enamel Microabrasion 09/01/2013 - "To compare in vivo the efficacy of enamel microabrasion alone or in combination with vital tooth bleaching for the management of tooth discoloration caused by fluorosis. "
3.	Lasers (Laser) 09/01/1993 - "Tooth discoloration and resolution following a luxation injury: significance of blood pigment in dentin to laser Doppler flowmetry readings." 03/27/2014 - "The purpose of this study was to evaluate the bleaching efficiency of two different lasers (KTP and diode 810 nm) on teeth, randomly divided by means an Excel function (Microsoft Excel 2010 "Fx causale") and stored in physiological solution, that were previously stained with different substances commonly considered as a cause of tooth discoloration, such as coffee, tea and red fruits and to investigate the role of laser irradiation in an experimental model, during the dental bleaching process. "
4.	Dental Pulp Capping 04/01/2015 - "The aim of this study was to evaluate tooth discoloration induced by contact with various calcium silicate-based pulp capping materials in the presence or absence of blood in vitro. " 04/01/2015 - "Tooth discoloration induced by calcium-silicate-based pulp-capping materials." 05/01/2015 - "Furthermore, none of the teeth treated with PCL-FM/MTA direct pulp capping showed tooth discoloration after treatment for 3 months. "
5.	Solid-State Lasers 03/27/2014 - "The purpose of this study was to evaluate the bleaching efficiency of two different lasers (KTP and diode 810 nm) on teeth, randomly divided by means an Excel function (Microsoft Excel 2010 "Fx causale") and stored in physiological solution, that were previously stained with different substances commonly considered as a cause of tooth discoloration, such as coffee, tea and red fruits and to investigate the role of laser irradiation in an experimental model, during the dental bleaching process. "