Tongue Neoplasms (Tongue Neoplasm)

01/01/2015 - "This study aimed to investigate the therapeutic efficacy of paclitaxel in combination with carboplatin in different ways in rabbits with VX-2 tongue cancer. "
01/01/2015 - "Therapeutic efficacy of paclitaxel and carboplatin via arterial or venous perfusion in rabbits with VX-2 tongue cancer."
08/01/2008 - "To assess the efficacy of paclitaxel, ifosfamide, and cisplatinum induction chemotherapy plus concurrent chemoradiation in the treatment of stage III and IV base of tongue cancer. "
08/01/2008 - "Treatment of base of tongue cancer with paclitaxel, ifosfamide, and cisplatinum induction chemotherapy followed by chemoradiotherapy."
08/01/2003 - "Combination therapy with paclitaxel and PKI166 prolongs survival in an orthotopic preclinical model of tongue cancer by increasing programmed cell death of oral cancer."

11/01/2008 - "Thus, the purpose of this study was to search for further genes involved in cisplatin resistance by differential gene expression analysis of the parental tongue cancer cell line Cal27 and its 10-fold more resistant sub-cell line Cal27cis, which was obtained by treating Cal27 with increasing concentrations of cisplatin. "
04/01/2015 - "In one case, the HFT method was applied to locally advanced tongue cancer, and the Seldinger method was used for additional administration of cisplatin (CDDP) to compensate for a lack of drug flow in the HFT method. "
04/01/2014 - "RIPK4 is downregulated in poorly differentiated tongue cancer and is associated with migration/invasion and cisplatin-induced apoptosis."
11/01/2011 - "Tongue cancer resistance-associated protein 1 (TCRP1) is a novel gene located on human chromosome 11q13.4 which has been reported as a candidate related to chemotherapeutic resistance to cisplatin. "
07/01/2011 - "Superselective arterial cisplatin infusion with concomitant radiation therapy for base of tongue cancer."

09/01/2007 - "[Proteomics study of the serum biomarkers in tongue cancer]."
10/01/2012 - "Role of FDG-PET as a biological marker for predicting the hypoxic status of tongue cancer."
04/01/2011 - "The role of salivary cytokine biomarkers in tongue cancer invasion and mortality."
05/01/2010 - "This review focuses on some promising predictive and prognostic biomarkers of tongue cancer and their actual/potential clinical implications, in order to provide clinicians with useful information for the improvement of early diagnostic/prognostic evaluation and management of patients with tongue cancer."
05/01/2010 - "Biomarkers in tongue cancer: understanding the molecular basis and their clinical implications."

04/01/2014 - "Our results suggest that examination of immunohistochemical expression of COX-2 and VEGF-C predicts LNM and survival in human oral tongue cancers."
04/01/2014 - "Forty tongue cancer specimens were immunohistochemically examined for COX-2 and VEGF-C expression and for lymphatic vessel density (LVD). "
12/01/2011 - "COX-2 Gene increases tongue cancer cell proliferation and invasion through VEGF-C pathway."
10/01/2015 - "On the other hand, we believe that tumor depth of invasion (≥4 mm), POI, and VEGF-C expression all need to be considered in the preoperative and postoperative planning stages for tongue cancer treatment."
10/01/2015 - "Vascular endothelial growth factor C (VEGF-C) expression predicts metastasis in tongue cancer."

06/01/2008 - "Treatment results of continuous intra-arterial CBDCA infusion chemotherapy in combination with radiation therapy for locally advanced tongue cancer."
01/01/2015 - "This study aimed to investigate the therapeutic efficacy of paclitaxel in combination with carboplatin in different ways in rabbits with VX-2 tongue cancer. "
01/01/2015 - "Therapeutic efficacy of paclitaxel and carboplatin via arterial or venous perfusion in rabbits with VX-2 tongue cancer."
01/01/2008 - "We present the case of a patient treated with definitive intensity modulated radiation therapy and concurrent carboplatin and fluorouracil for a locally advanced oral cavity and base of tongue cancer. "
09/01/1998 - "We measured the platinum concentrations in resected tumour tissues after infusion of carboplatin (CBDCA) at 20 mg/m2 over 30 min from 30 min before tumour resection in 12 patients with cancer of the tongue (6 patients: superselective intra-arterial infusion; 6 patients: conventional intra-arterial infusion). "

08/01/2011 - "In this study, we treated human brain metastasis of tongue cancer cell lines (Tb cells) with R5 at different concentrations, and the control Tb cells were treated with 10 mg/ml immunoglobin G 2b (IgG2b). "
01/01/2010 - "Natural killer cells are crucial for the efficacy of Icon (factor VII/human IgG1 Fc) immunotherapy in human tongue cancer."

04/01/1985 - "The dose and volume data of 119 patients treated with radium or iridium-192 implants for cancer of the tongue, bladder or perineum are presented. "
08/01/1957 - "Radium treatment of cancer of the tongue."
05/01/1953 - "Radium in the treatment of cancer of the tongue."
12/06/1930 - "RADIUM AND SURGERY IN CANCER OF THE TONGUE."
12/01/1930 - "RADIUM AND SURGERY IN CANCER OF THE TONGUE."

01/01/2008 - "We present the case of a patient treated with definitive intensity modulated radiation therapy and concurrent carboplatin and fluorouracil for a locally advanced oral cavity and base of tongue cancer. "
10/01/2012 - "Efficacy of multidrug superselective intra-arterial chemotherapy (docetaxel, cisplatin, and 5-fluorouracil) using the Seldinger technique for tongue cancer."
01/01/2004 - "In conclusion, induction chemotherapy with docetaxel, cisplatin and 5-FU for tongue cancer was tolerated well by all the patients and showed an excellent response rate in spite of only one cycle of administration."
01/01/2004 - "Induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil for tongue cancer."
09/01/2006 - "[Superselective intra-arterial infusion therapy with docetaxel, cisplatin and 5-fluorouracil for head and neck cancer--for tongue cancer patients in comparison patients with other therapies]."

06/01/2015 - "Therapeutic Efficacy of Orally Delivered Doxorubicin Nanoparticles in Rat Tongue Cancer Induced by 4-Nitroquinoline 1-Oxide."
09/01/2001 - "To investigate the effects of pegylated liposmal doxorubicin (PLD) in treating animal model of tongue cancer. "
05/01/2015 - "Incubation of tongue cancer cells CAL 27 and SCC-25 in medium containing doxorubicin, 5-fluorouracil, trichostatin A, or etoposide significantly increased the expression of miR-375 and its primary transcript pri-miR-375. "
11/01/2010 - "To understand the mechanisms responsible for drug resistance in tongue cancer, Tca8113 cells derived from moderately differentiated human tongue squamous cell carcinoma were exposed to stepwise escalated concentrations of pingyangmycin (PYM) to develop the resistant cell line called Tca8113/PYM, which showed over 18.78-fold increased resistance to PYM as compared with Tca8113 cells, and cross-resistance to cisplatin, pirarubicin, paclitaxel, adriamycin, and mitomycin. "

10/01/2012 - "Efficacy of multidrug superselective intra-arterial chemotherapy (docetaxel, cisplatin, and 5-fluorouracil) using the Seldinger technique for tongue cancer."
01/01/2004 - "In conclusion, induction chemotherapy with docetaxel, cisplatin and 5-FU for tongue cancer was tolerated well by all the patients and showed an excellent response rate in spite of only one cycle of administration."
01/01/2004 - "Induction chemotherapy with docetaxel, cisplatin and 5-fluorouracil for tongue cancer."
09/01/2006 - "[Superselective intra-arterial infusion therapy with docetaxel, cisplatin and 5-fluorouracil for head and neck cancer--for tongue cancer patients in comparison patients with other therapies]."
06/01/2005 - "Subjects were 20 patients with tongue cancer treated between April 1996 and December 2002 with intraarterial infusion of cisplatin (60-120 mg/m2) (and docetaxel 10-30 mg/m2) and intravenous infusion of sodium thiosulfate followed by 5-fluorouracil (5-FU) (800-1000 mg/m2) for 3 to 5 days. "

10/01/2005 - "A retrospective study was conducted to compare the efficacy of low-dose-rate brachytherapy (LDR), high-dose-rate brachytherapy (HDR), and surgery for early tongue cancer. "
07/01/2001 - "Reirradiation with a second course of brachytherapy may be useful in the treatment of patients with tongue cancer that recurs more than 12 months after initial brachytherapy."
06/01/2008 - "Low-dose-rate (LDR) brachytherapy is an effective treatment for tongue cancer. "
07/01/2001 - "The purpose of this study was to assess the efficacy of reirradiation with brachytherapy in the treatment of patients with tongue cancer that had recurred after initial brachytherapy. "
03/01/2014 - "High-dose-rate interstitial brachytherapy for mobile tongue cancer: preliminary results of a dose reduction trial."

03/30/2015 - "These data provide a rationale for targeted intervention on miR-491-3p/mTORC2 axis to enhance the efficacy of chemotherapy against tongue cancer. "
11/01/2010 - "Thus, our study suggests that the resistance of Tca8113/PYM cells is probably associated with CA9 and other differential expression molecules, and that CA9 may be an important marker for prediction of PYM responsiveness in tongue cancer chemotherapy."
01/01/2002 - "The aim of this study was to evaluate the role of the inductive chemotherapy in the treatment of advanced tongue cancer. "
08/21/2015 - "Here we demonstrated that chemotherapy induced 14-3-3σ expression in tongue cancer (TC) cells and overexpressed 14-3-3σ sensitized TC cells to chemotherapy especially in multidrug resistant TC (MDR-TC) cells. "
01/01/2015 - "Immunomodulated anterior chemotherapy followed by concurrent chemoradiotherapy in locally advanced tongue cancer: An Institutional experience."

07/01/2009 - "Although radical radiotherapy is known to be equally effective for early-stage oral tongue cancers (T1-2 N0) with the added advantage of organ and function preservation, surgery remains the preferred treatment. "
12/01/2014 - "To evaluate the efficacy of definitive radiotherapy (RT) for the treatment of base of the tongue cancer in a private practice. "
10/01/2014 - "This prospective analytical study included a total of 72 patients affected by oral tongue cancer (T1-2N0M0) who underwent treatment [wide local excision with selective + radiotherapy (RT)] from 2009 to 2012 at the Department of Oncosurgery and Otorhinolaryngology-Head and Neck Surgery, Sir Ganga Ram Hospital, New Delhi. "
11/01/2008 - "In this study, the results of definitive radiotherapy (RT) and salvage surgery treatment of base of tongue cancer were evaluated. "
01/01/2007 - "The study included 60 patients (31 males, 29 females; median age 54 years; range 22 to 82 years) who underwent surgery and postoperative radiotherapy for oral tongue cancer. "

01/01/2015 - "The study included 95 subjects with tongue cancer who underwent wide excision and neck dissection. "
05/01/2009 - "The aim of this study is to determine the need for a randomized controlled trial in order to define the role of an elective neck dissection (END) in the treatment of early tongue cancers. "
11/01/2015 - "The second case involved a 61-year-old man with tongue cancer who underwent mouth floor mass excision and right supraomohyoid neck dissection with submental flap reconstruction. "
10/01/2014 - "SNNS provides useful information regarding decision-making for neck dissection in early stage tongue cancer."
07/01/2013 - "One hundred thirty-eight patients who were treated with surgical excision of primary tongue cancer and neck dissection were analyzed retrospectively. "

01/01/2015 - "Tongue cancer is known to negatively affect both speech and swallowing function; however this is the first review to report speech-language pathology (SLP) intervention for both functions following partial glossectomy. "
01/01/2015 - "The anterior lateral thigh flap sensitive myocutaneous (ALTF) with vastus lateralis muscle was used to reconstruct the oral defect in a patient undergoing total glossectomy with laryngeal preservation for T4 tongue cancer. "
01/01/2015 - "Successful tongue reconstruction after total glossectomy for advanced tongue or base of tongue cancer should restore swallowing, speech function, and cosmesis. "
10/01/2014 - "A total of 63 patients with the mobile tongue cancer who underwent partial glossectomy without reconstruction were interviewed to score their swallowing and articulation function on a 100-point scale. "
04/01/2013 - "Although this retrospective study include a limited number of patients, the results support the validity of total glossectomy as a safe procedure for advanced cancer of the tongue. "