Tinea Versicolor

A common chronic, noninflammatory and usually symptomless disorder, characterized by the occurrence of multiple macular patches of all sizes and shapes, and varying in pigmentation from fawn-colored to brown. It is seen most frequently in hot, humid, tropical regions, and is caused by Pityrosporon orbiculare. (Dorland, 27th ed)

Also Known As:

Networked: 303 relevant articles (57 outcomes, 46 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Infection
2.	Tinea (Ringworm)
3.	Pityriasis
4.	Cutaneous Candidiasis
5.	Dermatomycoses (Dermatophytosis)

Experts

1.	Mayser, Peter: 7 articles (01/2011 - 05/2002)
2.	Krämer, Hans-Joachim: 5 articles (01/2011 - 05/2002)
3.	Mayser, P: 4 articles (06/2015 - 09/2000)
4.	Steglich, Wolfgang: 4 articles (12/2005 - 05/2002)
5.	Irlinger, Bernhard: 4 articles (12/2005 - 05/2002)
6.	Gupta, A K: 4 articles (08/2004 - 01/2000)
7.	Gupta, Aditya K: 3 articles (07/2015 - 09/2003)
8.	Faergemann, Jan: 3 articles (12/2009 - 01/2002)
9.	Jain, V K: 3 articles (07/2003 - 11/2000)
10.	Shi, Tian-Wei: 2 articles (04/2015 - 01/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tinea Versicolor:

1.	Ketoconazole (Nizoral)FDA LinkGeneric 12/01/1998 - "Ketoconazole 2% shampoo, used as a single application or daily for 3 days, is safe and highly effective in the treatment of tinea versicolor." 07/01/2014 - "Ketoconazole 2% foam improved overall clinical assessment and microscopic evidence of pityriasis versicolor in all subjects with favorable patient feedback regarding the novel foam vehicle." 07/01/2003 - "Both topical and systemic ketoconazole are reported to be effective against pityriasis versicolor. " 05/01/1984 - "Ketoconazole--an effective treatment for disseminated pityriasis versicolor." 12/01/1998 - "The topical short-term application of ketoconazole 2% shampoo may provide effective and safe therapy for tinea versicolor. "
2.	Itraconazole (Sporanox)FDA LinkGeneric 01/01/1987 - "Itraconazole appears to be effective in a high percentage of cases of pityriasis versicolor." 01/01/2010 - "Both single dose and 7 day daily dose of itraconazole can be effective in the treatment of tinea versicolor with extensive involvement but single dose appears to be better for improving compliance and decreasing the cost of treatment." 12/01/2002 - "This study has shown that a short course of itraconazole, 400 mg/day for 3 days, appears to be an effective and alternative treatment for pityriasis versicolor." 12/01/2002 - "Itraconazole is an oral antifungal agent, which has been proved to be effective in pityriasis versicolor. " 01/01/2010 - "A clinical study was done to compare the efficacy of single dose (400 mg) of itraconazole and 7 day 200 mg daily dose of itraconazole in the treatment of extensive tinea versicolor. "
3.	terbinafine (Lamisil)FDA LinkGeneric 03/01/2002 - "One-week terbinafine 1% solution in pityriasis versicolor: twice-daily application is more effective than once-daily." 11/01/1997 - "Malassezia furfur, the fungus causing pityriasis versicolor, has been reported to be sensitive to terbinafine in vitro but although topical therapy is effective in the treatment of pityriasis versicolor, oral therapy is not. " 01/01/1997 - "Terbinafine is also effective against pityriasis versicolor and vaginal candidosis, but only topically. " 01/01/1997 - "A prospective randomised placebo-controlled double-blind study was designed to investigate whether topical terbinafine 1% solution is an effective treatment for subjects with pityriasis versicolor. " 01/01/1997 - "We conclude that terbinafine 1% solution is an effective and safe local treatment modality for pityriasis versicolor."
4.	Fluconazole (Zonal)FDA LinkGeneric 01/01/1999 - "In a double blind randomised study to assess the efficacy of single dose fluconazole therapy, 30 patients of tinea versicolor (TV) were enrolled and were assigned into 2 groups. " 01/01/2009 - "A study to evaluate the efficacy and safety of oral fluconazole in the treatment of tinea versicolor." 01/01/2005 - "This study was designed to assess the efficacy, tolerability, and safety of oral fluconazole given at 300 mg once weekly for two weeks in the treatment of tinea versicolor. " 01/01/1999 - "Comparative evaluation of single dose regimen with two dose regimen of fluconazole in the treatment of tinea versicolor: A double blind placebo controlled study." 01/01/2005 - "We believe that, due to the low incidence of side effects, shorter treatment duration, and increased adaptation of the patients, fluconazole can be used in the treatment of tinea versicolor with confidence."
5.	bifonazoleIBA 01/01/1984 - "Bifonazole cream 1% was shown to be significantly more effective in the treatment of tinea versicolor when used nightly for 2 weeks than was the vehicle cream." 12/01/2002 - "Use of 1% bifonazole gel can be effective and safe in treating tinea versicolor in infants." 01/01/1984 - "This study demonstrates that bifonazole solution is an effective and well-tolerated form of treatment for pityriasis versicolor. " 12/01/2002 - "Twenty-two infants with tinea versicolor were treated with 1% bifonazole gel for 2 weeks, and the therapeutic effects were evaluated. " 12/01/2002 - "To evaluate the efficacy and safety of 1% bifonazole gel in the treatment of tinea versicolor in infants. "
6.	imidazoleIBA 11/01/2015 - "The objective of this research was to evaluate the efficacy of a new antifungal imidazole, dapaconazole tosylate, in the treatment of Pityriasis versicolor (PV). " 12/15/1988 - "In a clinical study from October 1985 to July 1987, we tested the efficacy of 3 different imidazole compounds in 112 male patients suffering from pityriasis versicolor. " 12/15/1988 - "[Local therapy of pityriasis versicolor with 3 imidazole derivatives--results of a therapeutic study. " 01/01/1986 - "It is a member of the imidazole series and is active in superficial and deep mycotic diseases, in candidosis and pityriasis versicolor. " 01/01/1986 - "This new imidazole derivative has been successfully administered in several cases of dermatophytosis, yeasts and pityriasis versicolor in the authors' clinic, as well as in many other research centres. "
7.	fenticonazoleIBA 09/01/1989 - "[Efficacy of fenticonazole in patients with pityriasis versicolor]." 09/01/1989 - "Thirty patients suffering from Pityriasis versicolor were treated with fenticonazole in cream or lotion form with two applications a day. " 01/01/1987 - "Clinical efficacy of fenticonazole 2% cream has been tested on 30 patients with dermatomycoses and the 2% nebulized lotion on 10 patients with pityriasis versicolor. " 01/01/2008 - "In particular, fenticonazole is very effective (often with 100% of patients achieving a negative mycological assay) in pityriasis versicolor and candidiasis. " 01/01/1987 - "Clinical experience with fenticonazole 2% formulation in the treatment of dermatomycoses and pityriasis versicolor."
8.	1- (4- (4- (4- ((4- (2,4- difluorophenyl)- 4- (1H- 1,2,4- triazol- 1- ylmethyl)- 1,3- dioxolan- 2- yl)methoxy)phenyl)piperazin- 1- yl)phenyl)- 3- (1- methylethyl)- 2- imidazolidinoneIBA 12/01/2009 - "Pramiconazole is a well-tolerated and effective treatment for pityriasis versicolor and the most effective treatment regimen in this study included 200 or 400 mg taken once, and 200 mg taken once daily for 2 or 3 days." 06/01/2007 - "The efficacy of oral treatment with pramiconazole in pityriasis versicolor: a phase II a trial." 12/01/2009 - "A double-blind, randomized, placebo-controlled, dose-finding study of oral pramiconazole in the treatment of pityriasis versicolor." 12/01/2009 - "Pramiconazole is a broad-spectrum triazole antifungal with potential for oral treatment of pityriasis versicolor. " 09/01/2008 - "Barrier Therapeutics was developing an oral formulation of pramiconazole for the potential treatment of seborrheic dermatitis (erythematosquamous skin disease), onychomycosis and dermatomycosis (including tinea versicolor, tinea pedis and tinea cruris/corporis). "
9.	selenium disulfide (Head & Shoulders)FDA LinkGeneric 01/01/1976 - "The results suggest that the selenium sulfide is absorbed poorly from the skin and is a safe and effective therapy for pityriasis versicolor." 08/01/1984 - "Double-blind efficacy study of selenium sulfide in tinea versicolor." 12/01/1995 - "Topical selenium sulfide lotion can also be used for tinea versicolor, which is often a recalcitrant problem." 08/01/1984 - "Twenty male patients with a diagnosis of tinea versicolor were randomly assigned to two parallel groups who applied selenium sulfide lotion or the vehicle to the entire skin surface, excluding mucous membranes, for 10 minutes once daily for 7 consecutive days. " 08/01/1984 - "Selenium sulfide in tinea versicolor: blood and urine levels."
10.	sertaconazoleFDA Link 05/01/1992 - "Therapeutic efficacy and safety of the new antimycotic sertaconazole in the treatment of Pityriasis versicolor." 05/01/1992 - "The activity of 7-chloro-3-[1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl) ethoxy-methyl]benzo[b]thiophene (sertaconazole, FI-7045, CAS 99592-32,2) was studied in a randomized parallel double-blind clinical trial on 21 patients suffering from Pityriasis versicolor (confirmed by KOH microscopic examination and exploration with Wood's light). " 04/01/2013 - "Sertaconazole is a broad-spectrum third-generation imidazole derivative that is effective and safe for the treatment for superficial mycoses, such as tineas, candidiasis, and pityriasis versicolor. "

Therapies and Procedures

1.	Epidural Analgesia 07/01/2011 - "We report the case of a pregnant woman with a tinea versicolor in the lumbar region, who benefited from a labor epidural analgesia, realised with reinforced antiseptic measures. " 07/01/2013 - "Epidural analgesia in a parturient with lumbar tinea versicolor." 07/01/2011 - "[Labor epidural analgesia for a woman with a pityriasis versicolor in the lumbar region]."
2.	Oral Administration 03/01/1990 - "Oral administration of itraconazole (100 mg once daily) was also highly efficacious in the treatment of pityriasis versicolor. "
3.	Transplantation (Transplant Recipients) 08/01/2012 - "We here report a case of pityriasis versicolor in a renal transplant recipient on penile shaft, which is an unusual area." 08/01/2012 - "Pityriasis versicolor on penile shaft in a renal transplant recipient." 06/01/2009 - "In this study, pityriasis versicolor was the most common skin infection in renal transplant recipients in our region. " 08/01/2003 - "Pityriasis versicolor and oral candidiasis were significantly more common among the renal transplant recipients, whereas the frequency of dermatophytosis in patients and controls was similar. " 08/01/2003 - "Sixty-five (63.7%) of the 102 renal transplant recipients had cutaneous-oral candidiasis, dermatophytosis, or pityriasis versicolor, whereas only 27 (30.7%) of controls had fungal infection. "
4.	Transplants (Transplant) 01/01/1981 - "This is an additional case of tinea versicolor appearing in a renal transplant patient undergoing immunosuppressant therapy. " 01/01/2015 - "Cutaneous infections are most commonly caused by Pityriasis (tinea) versicolor, dermatophytes, and candida sp but these days the demtiaceous fungi are becoming more frequently reported .Here we report a case of post renal transplant cutaneous infection caused by dematiaceous fungus belonging to the order Pleosporales. "
5.	Aftercare (After-Treatment) 04/01/2010 - "As she had continued progression of her hypopigmented lesions after treatment for pityriasis versicolor, a thorough physical examination (under room light and Wood's lamp) and repeat biopsy were performed. " 01/01/1976 - "[Levels of selenium in urine after treatment of pityriasis versicolor with a 1.0% selenium sulfide]."