Tinea (Ringworm)

A general term describing various dermatophytoses. Specific types include TINEA CAPITIS (ringworm of the scalp), TINEA FAVOSA (of scalp and skin), TINEA PEDIS (athlete's foot), and tinea unguium (see ONYCHOMYCOSIS, ringworm of the nails). (Dorland, 27th ed)

Also Known As:

Networked: 693 relevant articles (85 outcomes, 83 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Tinea Pedis (Athlete's Foot)
2.	Infection
3.	Tinea Versicolor
4.	Tinea Capitis
5.	Onychomycosis (Tinea Unguium)

Experts

1.	Hiruma, Masataro: 7 articles (01/2015 - 01/2003)
2.	Singal, Archana: 4 articles (03/2015 - 01/2005)
3.	Das, Shukla: 3 articles (03/2015 - 01/2005)
4.	Yamaguchi, Hideyo: 3 articles (06/2012 - 01/2002)
5.	Ogawa, Hideoki: 3 articles (07/2011 - 01/2003)
6.	Gupta, A K: 3 articles (08/2004 - 07/2000)
7.	Nanjoh, Yasuko: 2 articles (10/2015 - 06/2012)
8.	Kye, Young Chul: 2 articles (06/2015 - 01/2013)
9.	Sonthalia, Sidharth: 2 articles (03/2015 - 10/2014)
10.	Kano, Rui: 2 articles (01/2015 - 01/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Tinea:

1.	terbinafine (Lamisil)FDA LinkGeneric 11/01/1994 - "Our results show that 1-week therapy with oral terbinafine is highly effective in the treatment of tinea cruris/corporis." 11/01/1994 - "To evaluate the efficacy of short-term therapy with oral terbinafine in cases of tinea cruris/corporis, 22 patients (21 male and one female) with mycologically proven tinea cruris/corporis, were included in the present study. " 01/01/1997 - "We conclude that a 1-week course of Lamisil 1% emulsion gel is significantly more effective in the treatment of tinea corporis/cruris than placebo gel in respect of complete cure, mycological cure and effective treatment." 02/01/1992 - "High cure rates have been obtained in a preliminary study with oral terbinafine, 0.25 g/d, for 12 months, which have cleared toenail tinea in 15 of 17 patients. " 10/01/2014 - "Our findings suggest that in vivo potency and efficacy of AS2077715 are equal to or greater than that of terbinafine, positioning AS2077715 as a good candidate for use in treating trichophytosis. "
2.	Itraconazole (Sporanox)FDA LinkGeneric 08/01/1994 - "This double-blind study was undertaken to determine whether a 2-week course of oral itraconazole would produce statistically significant clinical and mycologic improvement in the treatment of tinea corporis, tinea cruris, or both, over the results obtained with placebo. " 08/01/1994 - "Itraconazole 100 mg once daily is an effective agent for the treatment of tinea cruris and tinea corporis." 07/01/1993 - "It is concluded that itraconazole, given at a daily dose of 100 mg for 15 days, is effective in the treatment of tinea corporis and tinea cruris. " 01/01/1987 - "Itraconazole appeared to be effective in the treatment of tinea corporis. " 09/01/2003 - "The present study was designed to determine the lowest dose of orally administered itraconazole and the shortest duration of therapy necessary for treatment of tinea corporis and tinea cruris. "
3.	Griseofulvin (Grifulvin V)FDA LinkGeneric 05/01/2006 - "Our results show that topical griseofulvin preparations may be effective and safe in treating tinea circinata and that further large-scale studies may establish the high efficacy of the niosomal gel formulation." 07/01/1977 - "Two cases of tinea in the neonate treated successfully with griseofulvin." 01/01/2004 - "Griseofulvin has been the mainstay of treatment for tinea imbricata (TI) for decades; however, there have been few reports of efficacy of newer antifungals in the treatment of this condition. " 05/01/2006 - "To evaluate the efficacy of topical griseofulvin in the treatment of tinea circinata using three different vehicles for drug delivery. " 05/01/2006 - "Efficacy of topical griseofulvin in treatment of tinea corporis."
4.	Fluconazole (Zonal)FDA LinkGeneric 11/01/1992 - "Ninety-five adult out-patients with tinea corporis and/or tinea cruris participated in a multicentre open non-comparative study investigating the safety and efficacy of 1-4 once-weekly doses of oral fluconazole 150 mg. Trichophyton rubrum was isolated most frequently (67 of 86 mycologically evaluable patients). " 04/01/1997 - "Fluconazole 150 mg once weekly for 6 weeks is both clinically and mycologically effective in the treatment of tinea corporis and tinea cruris and few side-effects were reported." 08/01/2000 - "Fluconazole is effective and safe for primary prevention of tinea gladiatorum. " 07/01/1999 - "Fluconazole in a weekly dosing schedule should be considered in the first-line treatment of tinea gladiatorum." 09/01/2009 - "Over the course of this 10-year study, out of 373 participants using prophylactic fluconazole, the incidence rate of tinea gladiatorum dropped from 67.4% to 3.5%. "
5.	Clotrimazole (Lotrimin)FDA LinkGeneric 03/01/2007 - "Successful topical treatment of the tinea manus was started with clotrimazole-containing ointment." 02/08/2002 - "The Food and Drug Administration (FDA) is issuing a final rule amending the final monograph for over-the-counter (OTC) topical antifungal drug products to add the ingredient clotrimazole as generally recognized as safe and effective for the treatment of athlete's foot, jock itch, and ringworm. " 01/01/1977 - "Clotrimazole is a new antifungal agent which is effective topically in dermatophytosis, cutaneous candidiasis, and tinea vesicolor. " 11/01/2011 - "Amorolfine 0.25% cream is found to be safe and effective, like clotrimazole, when used topically in tinea corporis." 01/01/2005 - "Comparative efficacy of topical 1% butenafine and 1% clotrimazole in tinea cruris and tinea corporis: a randomized, double-blind trial."
6.	sertaconazoleFDA Link 01/01/2003 - "The aim of this multicentre, double-blind, vehicle-controlled study was to investigate the safety and efficacy of once-daily topical application of sertaconazole 2% cream compared with corresponding vehicle cream in the treatment of patients with tinea of glabrous skin. " 01/01/2009 - "In randomized, double-blind, multicentre trials of 3-6 weeks' duration (n = 127-383), a significantly greater number of patients with tinea of the glabrous skin and tinea pedis receiving topical 2% sertaconazole cream once or twice daily achieved a successful mycological cure compared with recipients of a placebo cream. " 01/01/2007 - "The objective of the study was to compare the efficacy of a solution containing 2% sertaconazole with the well established 2% sertaconazole cream formulation in patients with tinea corporis, tinea pedis interdigitalis, or a corresponding candidosis. " 01/01/2007 - "Comparative study of 2% sertaconazole solution and cream formulations in patients with tinea corporis, tinea pedis interdigitalis, or a corresponding candidosis." 11/01/2013 - "This clinical trial was carried out to study and compare the efficacy of topical terbinafine hydrochloride 1% cream and sertaconazole nitrate 2% cream in localized tinea corporis and tinea cruris and to know the adverse effects of these antifungal creams. "
7.	butenafine (Mentax)FDA Link 02/01/1997 - "Butenafine applied once daily for 2 weeks is effective in treating tinea cruris. " 02/01/1997 - "We compared the safety and efficacy of butenafine hydrochloride and its vehicle when used once daily for 2 weeks to treat tinea cruris. " 03/01/2003 - "Randomised controlled trial of topical butenafine in tinea cruris and tinea corporis." 08/01/1997 - "A randomized trial to assess once-daily topical treatment of tinea corporis with butenafine, a new antifungal agent." 02/01/1997 - "Butenafine 1% cream in the treatment of tinea cruris: a multicenter, vehicle-controlled, double-blind trial."
8.	naftifine (naftifine hydrochloride)FDA Link 09/15/1984 - "The antimycotic efficacy of Naftifine was compared with that of placebo in a double-blind randomized trial in 60 patients with Tinea pedum proved by culture and microscopic examination. " 10/01/2011 - "A double-blind, randomized, vehicle-controlled study evaluating the efficacy and safety of naftifine 2% cream in tinea cruris." 07/01/1990 - "Seventy patients with tinea cruris or tinea corporis were treated with naftifine cream 1% or vehicle once daily for 4 weeks in this double-blind, randomized study. " 07/01/1990 - "Once-daily naftifine cream 1% in the treatment of tinea cruris and tinea corporis." 09/01/2013 - "Two-week treatment using naftifine cream or gel, 2% has been shown to be efficacious in subjects with Tinea pedis and/or Tinea cruris, and in most cases, continued improvement has been observed following cessation of treatment for up to four weeks. "
9.	Ketoconazole (Nizoral)FDA LinkGeneric 03/01/2001 - "A prolonged treatment by ketoconazole had a successful resolution in 70% of cases; 1 case of ciliar tinea caused by Trichophyton violaceum. " 10/01/1993 - "A case of tinea nigra that responded to treatment with topical ketoconazole is presented." 10/01/1993 - "Tinea nigra: treatment with topical ketoconazole." 01/01/1983 - "Ketoconazole in the treatment of tinea corporis." 03/01/1995 - "Thirty-five dermatologists enrolled 256 patients to assess the safety and efficacy of ketoconazole 2 percent cream, applied once daily, in the treatment of tinea pedis, tinea cruris, and tinea corporis. "
10.	imidazoleIBA 12/01/1996 - "An investigation was carried out to determine whether or not here had been any changes in the susceptibility of clinically isolated strains of Trichophyton metagrophytes and Trichophyton rubrum (both leading causes of tinea) to bifonazole, an imidazole derivative and antifungal for topical use. " 10/01/1989 - "Sulconazole nitrate 1 percent cream, a new imidazole derivative, was tested in 117 Colombian Army soldiers with tinea cruris/corporis under hot, humid conditions. " 01/01/2002 - "Eberconazole, an imidazole derivative, is a topical antifungal agent that has been shown to be effective in clinical trials in patients with tinea infections. " 06/01/2012 - "Short-term therapy with luliconazole, a novel topical antifungal imidazole, in guinea pig models of tinea corporis and tinea pedis." 01/01/2002 - "Lanoconazole, an imidazole, is a topical agent with potential application in tinea infections and cutaneous candidiasis. "

Therapies and Procedures

1.	Radiotherapy 03/01/2013 - "Depilatory radiotherapy was used in the sixties as a treatment for ringworm in Tunisia. " 01/01/2007 - "Depilatory radiotherapy for ringworm was largely used before antifungals were available. " 04/01/1988 - "Mortality after radiotherapy for ringworm of the scalp." 10/01/1955 - "[Fifteen years of radiotherapy of tinea at the University of Sassari Dermosyphilopathic Clinic]." 01/01/1955 - "[Epilation in tinea by radiotherapy; physical study, dosimetry, results]."
2.	Withholding Treatment 09/01/2013 - "Two-week treatment using naftifine cream or gel, 2% has been shown to be efficacious in subjects with Tinea pedis and/or Tinea cruris, and in most cases, continued improvement has been observed following cessation of treatment for up to four weeks. "
3.	First Aid (Aids, First) 01/01/2007 - "The easy availability of these remedies provides a quick way of curing various minor complaints such as tooth-ache, belly and rheumatic pain and headaches and can also serve as first aid as cicatrizing, lenitive, haemostatic agents etc. The role in veterinary medicine is, on the contrary, more important: sores, ulcers, tinea, dermatitis, gangrenous wounds of cattle, and even respiratory ailments are usually cured by resort to plants."
4.	X-Ray Therapy 03/01/1951 - "[Visual disorders and transitory modifications of the ocular fundus by the action of roentgenotherapy on the cranium in children affected with ringworm]." 01/01/2007 - "The aim of this study was to characterize scalp tumors occurring after X-ray therapy for ringworm. " 07/01/1976 - "This study is a further investigation of radiation dose to various head structures in the children given X-ray therapy for tinea capitis (ringworm of the scalp). " 01/01/1952 - "Resistant animal-type ringworm infection of the scalp treated with x-ray therapy." 06/01/1978 - "To investigate the late effects of radiation to the head upon subclinical mental disorders, a psychiatric and psychometric evaluation was performed on 177 cases treated 10-29 years earlier for ringworm of the scalp by X-ray therapy (N :109) or, by chemotherapy (N :68). "
5.	Hair Removal (Depilation) 01/10/1961 - "[Treatment of ringworm of the scalp by depilation with x-rays. " 03/01/1960 - "[Dosimetric research on temporary roentgen depilation for the treatment of tinea]." 01/01/1960 - "[Roentgen epilation of the scalp in the treatment of ringworm. " 01/01/1951 - "[Roentgen-depilation in ringworm; technical note]." 05/01/1950 - "[Local treatment of tinea without depilation]."